DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and UST4r

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	NP_599206.2	Gene:	UST4r / 171397	RGDID:	620976	Length:	552	Species:	Rattus norvegicus

Alignment Length:	580	Identity:	142/580 - (24%)
Similarity:	238/580 - (41%)	Gaps:	93/580 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIIL---ALNIPDHWCTVPGRENTNFSLEE 95
            ||.|:.:.|..||:|.| ..|||   .|:..::..:||:   ...||.|.|.||..:|...|..:
  Rat     3 FQELLNQVGGLGRFQIL-QMVFV---VFTSVIVVPHIIIENFTAAIPSHRCWVPILDNVTVSDND 63

  Fly    96 WR--------DITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTK-TTEACQNGWSYDK 151
            .|        .|::|..:..|    ...|..|......:.|.:...|::|: .||.|.:||.||:
  Rat    64 SRILNQDKLLKISIPLDSHLR----LDKCRRFAQPQWHLLDLNDTFSSITEPDTEPCVDGWVYDR 124

  Fly   152 TWYESTIPTDHNWVCAKDLF--VTNV-FVVGRVTEVAGSFILGQMGDSYGRRFVYYISV------ 207
            :.:.||..|:.|.||.....  ||.: |::|   ...|..:.|.:.|.:||:|:...::
  Rat   125 SNFHSTTVTEWNLVCESQALNSVTKLSFMIG---AFIGGIVNGLLSDRFGRKFILKYALLQMAIT 186

  Fly   208 -----------VFCSLGRLGSIMCTSSYTWFLIMSGIVGLTVN---SLFQ--SPQIIGMEISREE 256
                       ::|||.             ||....:..:|||   .:|:  ||:.:.|
  Rat   187 ETCAGFAPNLFIYCSLR-------------FLAGMSLEPITVNINLLMFEWTSPKFLTM------ 232

  Fly   257 DRSRIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFR 321
                :....||..|.|..::..|.:..::|.......|:|....|:.::::.||.||||...:.:
  Rat   233 ----VTVLGSCAGSFGGMILAGLAFQFQNWHHLQLAMSVPIFFFLILTRWLSESARWLIVINKPQ 293

  Fly   322 EAIVQLQKIAKINGH------------RFDMTEKELAEIYSRDKQDVTYGIASLFAGWRLARNTT 374
            :.:.:|:|:|.|||.            |..| :|||.....|...      ..||....|.:...
  Rat   294 KGLKELKKVAHINGMKKSGDNITMEVVRTSM-KKELEAAKMRPSP------RDLFHTPILRKQIY 351

  Fly   375 IMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLIS 439
            |:.|...:..:|...:.:....::.|..|..:..|:..|...|:|.::.:..|||.|..|...:.
  Rat   352 ILSFIRLLFILSGVGVAIHLQHLSNNIELLQILISVSSILFSVIGHFVLNHIGRRITQMVIMFLR 416

  Fly   440 FVTCLPIIVYSTDERYENLMIYLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAI 504
            .::.|..|.  ..:..|.|...:|...:.|.||::...:|...|:.||.:|.|...:..:..|..
  Rat   417 GISILTAIF--APQEMETLRFIMAMMAEGLAALSYAANSLHANELLPTTLRATARGVIGMFGNIG 479

  Fly   505 GVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDK 564
            ..|||..:.| .:.....|:...|...:|.|...|.||||.:..|||...:..:..|..:
  Rat   480 FFLAPLCMML-ASYSPNLPWIFYGGFAILSGFIVLLLPETKNNPLPDCTHDVENDWKESR 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	128/536 (24%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	86/391 (22%)
UST4r	NP_599206.2	MFS_OAT	109..516	CDD:340932	104/442 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	5.010