Protein Alignment CG7084 and SLC22A31

DIOPT Version :10

• Sequence 1: NP_651016.1
• Gene: CG7084 / 42606
• FlyBaseID: FBgn0038938
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001371692.1
• Gene: SLC22A31 / 146429
• HGNCID: 27091
• Length: 446
• Species: Homo sapiens
• Alignment Length: 503
• Identity: 114/503 - (22%)
• Similarity: 191/503 - (37%)
• Gaps: 119/503 - (23%)

  Fly   132 WNSNLTKTTEACQNGWSYDKTWYESTIPTDH-----NWVCAKDLFVTNVFVVGRVTEVAGSFILG 191
            ||.       .|.:||.         :|.:.     .|                   :.|..|||
Human     9 WNL-------VCGDGWK---------VPLEQVSHLLGW-------------------LLGCVILG 38

  Fly   192 QMGDSYGRRFVYYISVVFCSLGRLGSIMCTSSYTWFLIMSGIVGLTVNSLFQSPQIIGMEISREE 256
            ...|.:|||.|:..|:|. :.|...|....:|:...|::..:.|.|:.....:..:..:|:.  :
Human    39 AGCDRFGRRAVFVASLVL-TTGLGASEALAASFPTLLVLRLLHGGTLAGALLALYLARLELC--D 100

  Fly   257 DRSRIAFFQSCGW--SIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVI---ESPRWLIS 316
            ...|:||....|.  .:||.|:|.|...::.|.....|.::.:.::|||..:..   |||.||::
Human   101 PPHRLAFSMGAGLFSVVGTLLLPGLAALVQDWRLLQGLGALMSGLLLLFWGFPALFPESPCWLLA 165

  Fly   317 KQRFREAIVQLQKIAKING-------HRFDMTEKELAEIYSRDKQDVTY---GIASLFAGWRLAR 371
            ..:...|...|.:.|:.:|       ...:....||..:.:|..|...:   |:......|   |
Human   166 TGQVARARKILWRFAEASGVGPGDSSLEENSLATELTMLSARSPQPRYHSPLGLLRTRVTW---R 227

  Fly   372 NTTIMGFSWCV---VAVSYFTLVLFSSRMAGNP-----FLNFLYQSIVEIPAYVVGRYMGDTYGR 428
            |..|:|||..|   :..|:        |.:..|     :|.:..::.:|..|.|......|..||
Human   228 NGLILGFSSLVGGGIRASF--------RRSLAPQVPTFYLPYFLEAGLEAAALVFLLLTADCCGR 284

  Fly   429 RFTNSVSFLISFVTCLPIIVYSTDERYENLMIYLATFIKFLNALTFFTV----NLQCLEIYPTCM 489
            |   .|..|.:.||.|..::.....:|  |..:...|:..|..|....|    :|...|::||.:
Human   285 R---PVLLLGTMVTGLASLLLLAGAQY--LPGWTVLFLSVLGLLASRAVSALSSLFAAEVFPTVI 344

  Fly   490 RQTGVALGTIL-ANAIGVLAPYLVYLGTTVDIRAPYYILGVLF----LLGGIGALFLPETLHKKL 549
            |  |..||.:| |..:|..|..|    .|:..|..:::..|:|    :|..:..|.|||:..:.|
Human   345 R--GAGLGLVLGAGFLGQAAGPL----DTLHGRQGFFLQQVVFASLAVLALLCVLLLPESRSRGL 403

  Fly   550 PDTMEEAGHFGKHDKFFSLPKPPQAAEKDDKLSSHPELTRLRRSETAP 597
            |.::::|                      |:|...|.|....|.:..|
Human   404 PQSLQDA----------------------DRLRRSPLLRGRPRQDHLP 429

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_651016.1	MFS_SLC22	146..542	CDD:340875	99/432 (23%)
SLC22A31	NP_001371692.1	MFS	9..383	CDD:475125	100/433 (23%)