Protein Alignment CG7084 and SLC22A12

DIOPT Version :10

• Sequence 1: NP_651016.1
• Gene: CG7084 / 42606
• FlyBaseID: FBgn0038938
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_006718493.1
• Gene: SLC22A12 / 116085
• HGNCID: 17989
• Length: 578
• Species: Homo sapiens
• Alignment Length: 590
• Identity: 142/590 - (24%)
• Similarity: 240/590 - (40%)
• Gaps: 106/590 - (17%)

  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLA----------FSGAMIYMNIILALNIPDHWCTVPGREN 88
            |..|::..|..||:|.|.....:..:.          ||.|           :|.|.|..|..:|
Human     3 FSELLDLVGGLGRFQVLQTMALMVSIMWLCTQSMLENFSAA-----------VPSHRCWAPLLDN 56

  Fly    89 T--------NFSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLTKT------ 139
            :        :.|.|....|::|...:.|..:    |..|:.     ..|...:.|.|.|
Human    57 STAQASILGSLSPEALLAISIPPGPNQRPHQ----CRRFRQ-----PQWQLLDPNATATSWSEAD 112

  Fly   140 TEACQNGWSYDKTWYESTIPTDHNWVC--------AKDLFVTNVFVVGRVTEVAGSFILGQMGDS 196
            ||.|.:||.||::.:.|||....|.||        |:.:::..:.|        |:...|...|.
Human   113 TEPCVDGWVYDRSIFTSTIVAKWNLVCDSHALKPMAQSIYLAGILV--------GAAACGPASDR 169

  Fly   197 YGRRFVY---YISV--------------VFC------SLGRLGSIMCTSSYTWFLIMSGIVGLTV 238
            :|||.|.   |:.:              |:|      :....|.:|.|.:....|......||..
Human   170 FGRRLVLTWSYLQMAVMGTAAAFAPAFPVYCLFRFLLAFAVAGVMMNTGTLRRSLTWRHAGGLHA 234

  Fly   239 NSLFQSPQIIG-MEISREEDRSRIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLL 302
            .|..:...::. ||.:....|..:....|.|:|.|..|...:.:.:|.|.....:.|:|..:..|
Human   235 GSRAEPLGLLAVMEWTAARARPLVMTLNSLGFSFGHGLTAAVAYGVRDWTLLQLVVSVPFFLCFL 299

  Fly   303 FSKYVIESPRWLISKQRFREAIVQLQKIAKINGHRF--DMTEKELAEIYSRDKQDVTYG-----I 360
            :|.::.||.|||::..|....:.:|.::|.|||...  |....|:  :.|..:::::.|     :
Human   300 YSWWLAESARWLLTTGRLDWGLQELWRVAAINGKGAVQDTLTPEV--LLSAMREELSMGQPPASL 362

  Fly   361 ASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQSIVEIPAYVVGRYMGDT 425
            .:|.....|...|.|....|.....::|.|.|....:..|.||..::..:|:|||.:....:...
Human   363 GTLLRMPGLRFRTCISTLCWFAFGFTFFGLALDLQALGSNIFLLQMFIGVVDIPAKMGALLLLSH 427

  Fly   426 YGRRFTNSVSFLISFVTCLPIIVYSTDERYENLMIYLATFIKFLNAL--TFFTVNLQCLEIYPTC 488
            .|||.|.:.|.|::.: |   |:.:|...:|...:..|..:..|..:  .|..:.:...|::||.
Human   428 LGRRPTLAASLLLAGL-C---ILANTLVPHEMGALRSALAVLGLGGVGAAFTCITIYSSELFPTV 488

  Fly   489 MRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPY---YILGVLFLLGGIGALFLPETLHKKLP 550
            :|.|.|.||.:.|....:|.|.:..||    :..|:   .:.|.:.:|.|:.||.||||....||
Human   489 LRMTAVGLGQMAARGGAILGPLVRLLG----VHGPWLPLLVYGTVPVLSGLAALLLPETQSLPLP 549

  Fly   551 DTMEE 555
            ||:::
Human   550 DTIQD 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_651016.1	MFS_SLC22	146..542	CDD:340875	105/439 (24%)
SLC22A12	XP_006718493.1	MFS_OAT	109..541	CDD:340932	108/449 (24%)