Protein Alignment CG7084 and SLC22A9

DIOPT Version :10

• Sequence 1: NP_651016.1
• Gene: CG7084 / 42606
• FlyBaseID: FBgn0038938
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_543142.2
• Gene: SLC22A9 / 114571
• HGNCID: 16261
• Length: 553
• Species: Homo sapiens
• Alignment Length: 608
• Identity: 150/608 - (24%)
• Similarity: 244/608 - (40%)
• Gaps: 127/608 - (20%)

  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALNIPDHWC--------TVPGRENTN 90
            ||.|:..||:..|:|.|.. ||:...|.:..:.:|.......||.|.|        ||...:...
Human     3 FQDLLGHAGDLWRFQILQT-VFLSIFAVATYLHFMLENFTAFIPGHRCWVHILDNDTVSDNDTGA 66

  Fly    91 FSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAWNSNLT--KTTEA----CQNGWSY 149
            .|.:....|::|..::.|..|    |..|..     ..|...:.|.|  .|::|    |.:||.|
Human    67 LSQDALLRISIPLDSNMRPEK----CRRFVH-----PQWQLLHLNGTFPNTSDADMEPCVDGWVY 122

  Fly   150 DKTWYESTIPTDHNWVC--------AKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVY--- 203
            |:..:.|||.|:.:.||        ||.:|:..:.|        |..:.|.:.|.:|||||.
Human   123 DRISFSSTIVTEWDLVCDSQSLTSVAKFVFMAGMMV--------GGILGGHLSDRFGRRFVLRWC 179

  Fly   204 YISV--------------VFCSLGRLGSIMCTSSYTWFLIMSGIVGLTVNSLFQSPQI-IGMEIS 253
            |:.|              ::|||..|..|...|..|..::   ::.......||:..| :||
Human   180 YLQVAIVGTCAALAPTFLIYCSLRFLSGIAAMSLITNTIM---LIAEWATHRFQAMGITLGM--- 238

  Fly   254 REEDRSRIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQ 318
               ..|.|||....|          |.:.:|.|.....:.|:|..::.|.|.:::||.||||...
Human   239 ---CPSGIAFMTLAG----------LAFAIRDWHILQLVVSVPYFVIFLTSSWLLESARWLIINN 290

  Fly   319 RFREAIVQLQKIAKINGHRFDM--------------TEKELAEIYSRDKQDVTYGIASLFAGWRL 369
            :..|.:.:|:|.|    ||..|              |.|:..|...:.|.    .:..:.....:
Human   291 KPEEGLKELRKAA----HRSGMKNARDTLTLEILKSTMKKELEAAQKKKP----SLCEMLHMPNI 347

  Fly   370 ARNTTIMGFSWCVVAVSYFTLVLFSSRMAGNPF-LNFLYQSIVEIPAYVVG---RYMGDTYGRRF 430
            .:..:::.|:.....::||.|.|....:..|.| |..|:.:::.:...|..   :||     .|.
Human   348 CKRISLLSFTRFANFMAYFGLNLHVQHLGNNVFLLQTLFGAVILLANCVAPWALKYM-----NRR 407

  Fly   431 TNSVSFLISFVTCLPIIVYSTDERYENLMIYLATF----IKFLNALTFFTVNLQCLEIYPTCMRQ 491
            .:.:..:.....||..|::...| .:.|...|||.    ....|.|.|...|    |:.||.:|.
Human   408 ASQMLLMFLLAICLLAIIFVPQE-MQTLREVLATLGLGASALANTLAFAHGN----EVIPTIIRA 467

  Fly   492 TGVALGTILANAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEEA 556
            ..:.:....||..|.|||.::.| :......|:.|.||...:.|...|.||||.:|.|.||:::.
Human   468 RAMGINATFANIAGALAPLMMIL-SVYSPPLPWIIYGVFPFISGFAFLLLPETRNKPLFDTIQDE 531

  Fly   557 GHFGKHDKFFSLPKPPQAAEKDD 579
                |:::     |.|:..:::|
Human   532 ----KNER-----KDPREPKQED 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_651016.1	MFS_SLC22	146..542	CDD:340875	107/443 (24%)
SLC22A9	NP_543142.2	MFS_OAT	109..517	CDD:340932	109/453 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	528..553		4/27 (15%)