Protein Alignment CG7084 and SLC22A7

DIOPT Version :9

• Sequence 1: NP_001247235.2
• Gene: CG7084 / 42606
• FlyBaseID: FBgn0038938
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: XP_011512558.1
• Gene: SLC22A7 / 10864
• HGNCID: 10971
• Length: 610
• Species: Homo sapiens
• Alignment Length: 646
• Identity: 160/646 - (24%)
• Similarity: 247/646 - (38%)
• Gaps: 184/646 - (28%)

  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILAL---NIPDHWCTVPGRENTNFSLEE 95
            |:.|:|:.|..|.:| |.|   |..||....::.::.:|.:   .:|.|.|.:||.. .|||.::
Human     3 FEELLEQVGGFGPFQ-LRN---VALLALPRVLLPLHFLLPIFLAAVPAHRCALPGAP-ANFSHQD 62

  Fly    96 -WRDITLPKQADNRGRKTFSNCEMF--------------QMNFSEITDWSAWNSNLTKTTEACQN 145
             |.:..||::.|.    |.|:|..|              :.:..|:.|..|        |..|..
Human    63 VWLEAHLPREPDG----TLSSCLRFAYPQALPNTTLGEERQSRGELEDEPA--------TVPCSQ 115

  Fly   146 GWSYDKTWYESTIPTDH----------------------------------------------NW 164
            ||.||.:.:.|||.|:.                                              :|
Human   116 GWEYDHSEFSSTIATESQVGIYIIHLEVECRWRQSPWEAAGRGLPWEEAEAAGLGRDKVSYSPSW 180

  Fly   165 ---------------VC--------AKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRR---FVY 203
                           ||        |...|...|.|        |:...|.:.|.:|||   .|.
Human   181 RESLGGLLSGMEWDLVCEQKGLNRAASTFFFAGVLV--------GAVAFGYLSDRFGRRRLLLVA 237

  Fly   204 YISVVFCSLGRLGSIMCTSSYTWFLIM-----SGIVGLTVNSLFQSPQIIGMEISRE-------E 256
            |:|.:...|....|:    ||..|.|.     |.:.|.|         ||.|.:...       |
Human   238 YVSTLVLGLASAASV----SYVMFAITRTLTGSALAGFT---------IIVMPLGEAELEWLDVE 289

  Fly   257 DRSRIAFFQSCGWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFR 321
            .|:......|..|:.|..|:.|:.:.:|.|...:...::|.|..:|...:|.||.|||:::...:
Human   290 HRTVAGVLSSTFWTGGVMLLALVGYLIRDWRWLLLAVTLPCAPGILSLWWVPESARWLLTQGHVK 354

  Fly   322 EAIVQLQKIAKINGHRFDMTEKELAEIYSRDKQDVTYGIASLFAGWRLARNTTIMG--------- 377
            ||...|...|::||      .....:.:|::      .::.:.||.|:.|..:.:.
Human   355 EAHRYLLHCARLNG------RPVCEDSFSQE------AVSKVAAGERVVRRPSYLDLFRTPRLRH 407

  Fly   378 FSWCVVAV------SYFTLVLFSSRMAGNPFLNFLYQSIVEIPA----YVVGRYMGDTYGRRFTN 432
            .|.|.|.|      ||:.|.|..|.:..|.:...|....||:|:    |:..||.    |||.|.
Human   408 ISLCCVVVWFGVNFSYYGLSLDVSGLGLNVYQTQLLFGAVELPSKLLVYLSVRYA----GRRLTQ 468

  Fly   433 SVSFL---ISFVTCLPIIVYSTDERYENLMIYLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGV 494
            :.:.|   ::|.|.|   :.|:|  .::....||...|..:...|.|..|...|:|||.:||||:
Human   469 AGTLLGTALAFGTRL---LVSSD--MKSWSTVLAVMGKAFSEAAFTTAYLFTSELYPTVLRQTGM 528

  Fly   495 ALGTILANAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGALFLPETLHKKLPDTMEE 555
            .|..::....|.||| |..|...|.:..|....|.:.||....||.||||...:||:|:::
Human   529 GLTALVGRLGGSLAP-LAALLDGVWLSLPKLTYGGIALLAAGTALLLPETRQAQLPETIQD 588

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	148/611 (24%)
		MFS	184..542	CDD:119392	105/394 (27%)
SLC22A7	XP_011512558.1	2A0119	11..585	CDD:273328	156/633 (25%)
		MFS	206..563	CDD:119392	105/399 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	5	5.020