DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7084 and slc22a20p.1

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	XP_004913725.1	Gene:	slc22a20p.1 / 100489586	XenbaseID:	XB-GENE-6463910	Length:	572	Species:	Xenopus tropicalis

Alignment Length:	561	Identity:	154/561 - (27%)
Similarity:	248/561 - (44%)	Gaps:	65/561 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    30 FNDPFQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALNIPDHWCTVPGRENTNFSLE 94
            |||    |:...|..||:|.::..:.:..:.|.|...::....|. :|.|.|.||..:|.....:
Frog     3 FND----LLLSVGGLGRFQIIHTTMLLIPMLFMGCHNFLQNFSAA-VPAHRCWVPSLDNNTMGYD 62

  Fly    95 EWRDITLPKQAD-NRGRKTFSNCEMFQMNFSEITDWSAW-NSNLTKTTEACQNGWSYDKTWYEST 157
            :..   ||.... :...|..| |..::....     |.| |...|..||.|::||.|||:.:.||
Frog    63 QDH---LPAFIPMDESEKPLS-CLRYRKALH-----SMWTNGTSTNHTEPCEDGWVYDKSDFSST 118

  Fly   158 IPTDHNWVC--------AKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYIS-VVFCSLG 213
            |.|:.:.||        |:.:::..|.|        |:.:||.:.|..|||.:...| :|....|
Frog   119 IVTEWDLVCKLRKMRQIAQSIYMAGVLV--------GAVLLGGLSDRLGRRALLIGSNLVMAVCG 175

  Fly   214 RLGSIM------CTSSYTWFLIMSGIVGLTVNSLFQSPQIIGMEISREEDRSRIAFFQSCGWSIG 272
            ...:.:      ||......:..|||. |..|||.       :|.:..:.|:.:....:.|::.|
Frog   176 TCAAFLPNFITYCTFRCLCGIAFSGIT-LNTNSLI-------LEWTPPKGRTIMGTLFAAGFTCG 232

  Fly   273 TTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKINGHR 337
            ..|:..|.:.:|.|....:..|.|.....|:|..|.||.||||.|.|..||:..||::|.|||.|
Frog   233 QILLAALAYGIREWRWLQFAVSAPFYFFFLYSWLVPESARWLILKGRSHEALKALQRVAIINGKR 297

  Fly   338 FD---MTEKELAEIYSRDKQDV--TYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRM 397
            .:   ::|..|......:...|  .:.:..||....:.:.|..:...|....|:::.|.:.....
Frog   298 EEGQKLSEMILISHMQSELNQVKRPHSLFDLFRTPGMRKVTICLMMVWFSSGVAFYGLGMDLQNF 362

  Fly   398 AGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCLPIIVYSTD----ERYENL 458
            ..:.||.......:::||.||...:....|||.|.:...::|.|..|      |:    :..:.|
Frog   363 GISIFLLQFTFGAIDMPAKVVAALLMTYMGRRVTQATVLILSGVALL------TNAFIPQGMKIL 421

  Fly   459 MIYLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAP 523
            .:.||.|.|...|.:|....|...|::||.:||||:.:..::|....|:|| ||.|...:....|
Frog   422 RMVLAVFGKGCMAASFACAYLFSGELFPTVIRQTGMGVVAMMARVGSVVAP-LVLLLWEISPILP 485

  Fly   524 YYILGVLFLLGGIGALFLPETLHKKLPDTME--EAGHFGKH 562
            ..|.|:..::.|..|.||.||.:::||:::|  ||...|||
Frog   486 SAIYGIAAIIAGGAATFLMETNNQQLPESVEEVEARSQGKH 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	138/513 (27%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	100/373 (27%)
slc22a20p.1	XP_004913725.1	MFS	101..485	CDD:391944	111/406 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000