DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and slc22a2

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	XP_002933908.1	Gene:	slc22a2 / 100487774	XenbaseID:	XB-GENE-965056	Length:	544	Species:	Xenopus tropicalis

Alignment Length:	544	Identity:	147/544 - (27%)
Similarity:	246/544 - (45%)	Gaps:	32/544 - (5%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALNIPDHWCTVPG-RENTNFSLEEWR 97
            |..|:|..|....:|... |:.:..::...:.||:.|:....:||:.|...| .|.:|..  ||
Frog     4 FDELLEHIGEFDAFQKQI-FILLCFISVVFSPIYVGIVFLGFVPDYRCVSAGIPEPSNEC--EW- 64

  Fly    98 DITLPKQADNRGRKT--FSNCEMFQMNFSEITDWSAWNSNLTKTTEA----CQNGWSYDKTWYES 156
              ||.....|....:  .|.|..:.::::. |..:..||:|..|::.    |::||.|:.|  .|
Frog    65 --TLNYTGPNGSTDSLYMSQCYQYDVDWNS-TSLNCTNSSLNITSKLPITNCKDGWDYNTT--GS 124

  Fly   157 TIPTDHNWVCAK----DLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSLGRLGS 217
            ::.|:.|.||..    |.|.:.|    .:....|..|.|.:.|.:||: .:.||.:..: |..|.
Frog   125 SLVTEFNLVCGDSWKLDFFQSCV----NIGFFIGGLISGYIADRFGRK-PFLISSILIT-GIFGI 183

  Fly   218 IMC-TSSYTWFLIMSGIVGLTVNSLFQSPQIIGMEISREEDRSRIAFFQSCGWSIGTTLMPLLYW 281
            :|. ..:|...:....|.|......:.|..|:..|....|.|..:.......:::|..|:..:.:
Frog   184 LMAFAPNYPLVVTFRFIQGFVSKGCWLSGYILVAEFVGLEHRRTVGIVYQAAFTVGLLLLSGVAY 248

  Fly   282 WLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKINGHRF-DMTEKEL 345
            .|.||.......:||....|.:...|.||||||||:.|..||...:..|||.||... |..|...
Frog   249 VLPHWRWLQMTVTIPYFFFLAYYWCVPESPRWLISQNRKAEAKAIIHTIAKKNGKMVPDFLESLT 313

  Fly   346 AEIYSRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQSI 410
            |:..:.:||..::  ..|....::.::|.|:.:.|...||.|...::.....|.|.:.:|...::
Frog   314 ADEEAGEKQVPSF--LDLVRTPQIRKHTLILMYIWFTCAVVYQGSIMHMGSTAENIYFDFFISAL 376

  Fly   411 VEIPAYVVGRYMGDTYGRRFTNSVSFLISFVTCLPIIVYSTDERYENLMIYLATFIKFLNALTFF 475
            ||.|:.::.....|..|||:...|..:|:.:|||  |.......|..|:|.|:...:....:::.
Frog   377 VEFPSAILIIVTVDRVGRRYPWLVCCIITGITCL--ITAFIPHGYSWLIITLSCVSRMGITVSYE 439

  Fly   476 TVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGALF 540
            .|.|...|:|||.:|..|:.:.:.:.:..||:.|::||....:....|..:..||..:.||...|
Frog   440 MVCLVNAELYPTFIRNLGIMVCSSMCDLGGVITPFIVYRLAAIWQELPLIVFAVLATVSGILVYF 504

  Fly   541 LPETLHKKLPDTMEEAGHFGKHDK 564
            ||||..:.||:|:|||.:..|..|
Frog   505 LPETKGRALPETIEEAENLHKQVK 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	135/500 (27%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	95/359 (26%)
slc22a2	XP_002933908.1	2A0119	12..516	CDD:273328	138/522 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000