Protein Alignment CG7084 and sv2ba

DIOPT Version :10

• Sequence 1: NP_651016.1
• Gene: CG7084 / 42606
• FlyBaseID: FBgn0038938
• Length: 597
• Species: Drosophila melanogaster
• Sequence 2: NP_001076464.1
• Gene: sv2ba / 100009626
• ZFINID: ZDB-GENE-070209-134
• Length: 689
• Species: Danio rerio
• Alignment Length: 729
• Identity: 131/729 - (17%)
• Similarity: 235/729 - (32%)
• Gaps: 303/729 - (41%)

  Fly     4 KKEQANSRKASQVSGHFSQMDVDDSEFNDPFQALMEKAGNHGRYQ-TLYNFVFVGGLAFSGAMIY 67
            |:.:..:|:.:::....: .:|::....|.::::||..| |||:| ||:..:   |||.
Zfish    70 KEARRAARREARMKARMA-AEVEEETLPDQYESIMEDCG-HGRFQWTLFTLL---GLAL------ 123

  Fly    68 MNIILALNIPDHWCTVPGRENTNFSLEEWRDITLPKQADNRGRKTFSNCEMFQMNFSEITDWSAW 132
                                                .||        ..|.|.::|:
Zfish   124 ------------------------------------MAD--------GVECFVVSFA-------- 136

  Fly   133 NSNLTKTTEACQNGWSYDKTWYESTIPTDHNWVCAKDLFVTNV--FVVGRVTEVA---GSFILGQ 192
                                     :|:     ..||:.::|.  .::|.:..|.   |:.:.|.
Zfish   137 -------------------------LPS-----AEKDMCLSNADKGMLGLIVYVGMMIGAVVWGG 171

  Fly   193 MGDSYGRR----FVYYISVVFCSLGRLGSIMCTSS----YTWFLIMSGI-VGLTVNSLF-QSPQI 247
            :.|..||:    :...|:.:|..|.      |.:.    :.:|.:.||| :|.::..:: ...:.
Zfish   172 LADKLGRKQCLLYALAINCIFSFLS------CFAQGYGFFIFFRLCSGIGIGGSIPVVYTYYAEF 230

  Fly   248 IGMEISREEDRSRIAFFQSCGWSIGTTLMPLLYW-------W---------LRHWDSFMWLTSIP 296
            :.|: .|.|..|.:..|    |.:|........|       |         ...|..|:.:..:|
Zfish   231 LQMD-KRGEHLSWLCLF----WMLGGLYASFTAWGIIPHYGWGFSMGTEFQFHSWRVFVLVCFLP 290

  Fly   297 TAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKINGHRFDMTEK--ELAEIYSRDKQD---- 355
            :...|....::.||||:|:...|..||.:.|:::...|.......|:  ::::|.:...||
Zfish   291 SVAALAGLVFMPESPRFLLESARHDEAWMILRRVHDTNWGAKGEPERVFQVSQIKTPQTQDDEFI 355

  Fly   356 -VTYGIASLFAGWRLARNTTI---------------------MGFSWCVVAVSYFTL-VLFSSRM 397
             :.....:.|..:.:.:.|.:                     :...|..:|.||:.| ..|..::
Zfish   356 EIQSETGTAFQRFMVRQMTLVKQVMKNMLSLAAPDVRLHGLFIAIVWFTMAFSYYGLGTWFPDQI 420

  Fly   398 AGNPFLNF-LYQSIVEI-----------------PAYVVGRYMGDTYGRRFTN----SVSFLIS- 439
               .:|.| .|:|.|:|                 ..:..|.|:.|    ||.|    :|.|..|
Zfish   421 ---KYLQFEEYESNVKIFHRERVERFHFNFTLQNQLHKEGEYVHD----RFINIEIRNVKFEDSL 478

  Fly   440 FVTCLPIIVYSTDERYEN---------------------------------------------LM 459
            |..|....:.||:..:||                                             ::
Zfish   479 FENCYFEDIKSTETFFENCTLKNTVFYNTDLWEDSKFINCNLENTTFLHPKKGCHLNFQEENDIL 543

  Fly   460 IYLATFIKFLNAL-----------------------------TFF---------TVNLQCL---- 482
            |||.:|:..|:.:                             |||         .|..|||
Zfish   544 IYLDSFLGSLSVIPGNILAGLLMDKIGRLKIIGGSMLGSAVCTFFLLLCFSQWAVVLFQCLFFAA 608

  Fly   483 -------------EIYPTCMRQT--GVALGTILANAIGVLAPYLV--YLGTTVDIRAPYYILGVL 530
                         |:||...|.|  ||..||....||  ::.::.  ::|.|..|  |..:....
Zfish   609 GAAAWNGIEVVTVELYPASKRATAFGVLNGTCKLAAI--ISSFIFGKFIGITKII--PIILSFSA 669

  Fly   531 FLLGGIGALFLPET 544
            .:.||:.|..||||
Zfish   670 LVCGGLLAFKLPET 683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_651016.1	MFS_SLC22	146..542	CDD:340875	106/582 (18%)
sv2ba	NP_001076464.1	synapt_SV2	36..689	CDD:130366	131/729 (18%)