DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and slc22a13a

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	XP_021322911.1	Gene:	slc22a13a / 100007819	ZFINID:	ZDB-GENE-070912-473	Length:	537	Species:	Danio rerio

Alignment Length:	573	Identity:	145/573 - (25%)
Similarity:	259/573 - (45%)	Gaps:	76/573 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 FQALMEKAGNHGRYQTLYNFVFVGGLAFSGAMIYMNIILALNI---------PDHWCTVPG--RE 87
            |..::|..|:.|.:|.|..|          |:.:.|:||...:         .:|.|....  :.
Zfish     4 FGEILEAIGDFGLFQKLLLF----------ALCFPNLILPFQLSSLVFNHADTNHHCNTDWILKA 58

  Fly    88 NTNFSLEEWRDITLPKQADNRGRKTFSNCEMFQ---MNFSEITDWSAWNSNLTKTTEACQNGWSY 149
            :.|.:.||..::|||:.:|.    :|:.|:|::   .|.|.|.::     .|.:|| .|.:||.:
Zfish    59 DPNLTKEEQLNLTLPRLSDG----SFNPCQMYKPVDWNLSAIQEY-----GLNQTT-TCTDGWVH 113

  Fly   150 DKTWYESTIPTDHNWVC--------AKDLFVTNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYIS 206
            :.|.||:||.||.:.||        |:.:|...|.|        |:.:.|...:|:||:....|.
Zfish   114 NDTIYEATIVTDFDLVCENVNIFRGAQTVFFAGVLV--------GAILFGPFSESFGRKRATQIP 170

  Fly   207 VVFCSLGRLGSIMCTSSYTW----FLIMSGIVGLTVNSLFQSPQIIGMEISREEDRSRIAFFQSC 267
            :|...:..:.:.:..:.|.:    |:...|:.|..:||:..:.:.||:     ..||..|.....
Zfish   171 MVLMLIFTVVTGLSPNFYVYLVSQFINGVGLGGFRINSIILASEWIGV-----AQRSYAACLSQV 230

  Fly   268 GWSIGTTLMPLLYWWLRHWDSFMWLTSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAK 332
            ..::|..:...:.:::|.|....::.:.|..:|:::..::.||.|||:.:.|.::|...:||.|.
Zfish   231 LAALGQVMFLAVVYFVRDWRLDQFIMAGPIGIVVIYIWFLPESARWLLDRGRTKDAKKLIQKAAA 295

  Fly   333 INGHRFDMTEKELAEIYSRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRM 397
            :|..   ...:.|.|...::|.....||..||....|.:....:.|:||.:.::|::|.|...:.
Zfish   296 VNKR---AVPESLVEEVLKEKPVEKGGIKILFGSRVLRKYFLAITFAWCALNLAYYSLSLNVGKF 357

  Fly   398 AGNPFLNFLYQSIVEIPAYVVGRYMGDTYGRRFTNSVSFLISFVT--CLPIIVYSTDERYENLMI 460
            ..:.||..|...:.|||.:.:..:..:..||:    .|.::|.|.  ||.::..:..:.....:.
Zfish   358 GLDIFLTQLIFGLSEIPVHFLCMWSLEVVGRK----PSLIVSLVLGGCLCLLTVAVPQNSSIAIA 418

  Fly   461 YLATFIKFLNALTFFTVNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPYY 525
            .|||..:||........|:...|::||.:|||...||:..|.|..:|:| :|.:........|..
Zfish   419 VLATCGRFLMNAAGSVCNVYFQELFPTSIRQTATGLGSTAARAGSMLSP-VVNMLEIFHFSIPMV 482

  Fly   526 ILGVLFLLGGIGALFLPETLHKKLPDTMEEAGHFGKHDKFFSLPKPPQAAEKD 578
            ::..|.|..|:.|..||||...:||.:.|||.  ||..     ||....|.:|
Zfish   483 VISSLALASGVTAFLLPETRRTELPASTEEAE--GKRK-----PKLTSPATRD 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	129/515 (25%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	85/363 (23%)
slc22a13a	XP_021322911.1	Sugar_tr	12..507	CDD:331684	132/535 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	5.020