DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7084 and slc22a5

DIOPT Version :9

Sequence 1:	NP_001247235.2	Gene:	CG7084 / 42606	FlyBaseID:	FBgn0038938	Length:	597	Species:	Drosophila melanogaster
Sequence 2:	XP_021324939.1	Gene:	slc22a5 / 100000685	ZFINID:	ZDB-GENE-091012-1	Length:	549	Species:	Danio rerio

Alignment Length:	534	Identity:	140/534 - (26%)
Similarity:	250/534 - (46%)	Gaps:	65/534 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    50 LYNFVFVGGLAFSGAMIYMNIILALNIPDHWCTVPGRENTNFSLEEWRDITLPKQADNRGRKTFS 114
            |.|.:::     |..:..:.|:.....|.|.|    |.:.|.: |:|.:.:.|.:..:.|....|
Zfish    24 LLNLIYI-----STGLHGLYIVFVAASPAHRC----RVDVNLT-EDWLEASAPTETLSNGDLQVS 78

  Fly   115 NCEMFQMNFSEITD-----WSAWNSNLTK-TTEACQNGWSYDKTWYESTIPTDHNWVCAKDLFV- 172
            .|  ::.:...:|:     :|....|:|. ..|.|::||.|....|.|||.::.:.||..:..|
Zfish    79 QC--WRYSLQTLTNLSGQGYSPGQINITDIPRERCEDGWVYSADVYHSTIVSEWDLVCDSEWRVP 141

  Fly   173 --TNVFVVGRVTEVAGSFILGQMGDSYGRRFVYYISVVFCSLGRLGSIMCTSSY--TW--FLIMS 231
              ::...:|   .:.||.:.||:.|.:||:     .|:|.||.....:|...|:  :|  |.::.
Zfish   142 LASSTLYMG---YLLGSIVSGQLSDRFGRK-----KVLFGSLAAEALLMFAQSFSPSWLIFCVLY 198

  Fly   232 GIVGLTVNSLFQSPQIIGMEISREEDRSRI----AFFQSCGWSIGTTLMPLLYWWLRHWDSFMWL 292
            ..:|....||:.:..::|.|:.....|...    ||...|   :|..|:|.:.:.:|||.:.:.:
Zfish   199 FFIGAFQISLYITAFVLGNEVLSGSLRVLFTTLGAFLHYC---VGYMLLPWVAFAIRHWRTLLRV 260

  Fly   293 TSIPTAMVLLFSKYVIESPRWLISKQRFREAIVQLQKIAKINGHRFDMTE--------KELAEIY 349
            .|..|.:.:.....:.||||||:|:...:|:...|:..|:.|  |....|        ||.|  :
Zfish   261 LSGLTVVYIPLWWLIPESPRWLLSQGHVQESEAILRDAARKN--RVPAPEVIFKQSQIKEAA--F 321

  Fly   350 SRDKQDVTYGIASLFAGWRLARNTTIMGFSWCVVAVSYFTLVLFSSRMAGNPFLNFLYQSIVEIP 414
            .:.|    |....:.....:.|.|.:....|..:.:.||.|.|.::.::|:||||....::.|:|
Zfish   322 QKSK----YSALDVLRTSNIRRTTFMCLLLWMAINIGYFGLSLNTTNLSGDPFLNCFLSAVTEVP 382

  Fly   415 AYVVGRYMGDTYGRRFTNSVSFLI---SFVTCLPIIVYSTDERYENLMIYLATFIKFLNALTFFT 476
            ||:|..::..:..||...| :||:   .|:    ::|....:|.:.|.:.|....||...::|..
Zfish   383 AYIVSTFLLKSCPRRPVLS-AFLVIGGGFL----LLVQLIPDRLQTLALALEMAGKFGFTMSFTV 442

  Fly   477 VNLQCLEIYPTCMRQTGVALGTILANAIGVLAPYLVYLGTTVDIRAPYYILGVLFLLGGIGALFL 541
            |.:...|:|||.:|..|:.:.:..|....:.|||:::|| |.:...||.::|.|.:...:..|||
Zfish   443 VYIYTAELYPTVLRNLGMGMCSSAARIGSITAPYIIFLG-TFNRHLPYVLMGSLTITASLANLFL 506

  Fly   542 PETLHKKLPDTMEE 555
            |||..|.||:.:|:
Zfish   507 PETFGKVLPENLEQ 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7084	NP_001247235.2	2A0119	64..552	CDD:273328	136/515 (26%)
CG7084	NP_001247235.2	MFS	184..542	CDD:119392	100/376 (27%)
slc22a5	XP_021324939.1	Sugar_tr	12..516	CDD:331684	138/528 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG57756
OrthoDB	1	1.010	-	-		D375160at33208
OrthoFinder	1	1.000	-	-		FOG0000012
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR24064
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X24
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	7	7.030