Protein Alignment Gld2 and Mtpap

DIOPT Version :10

• Sequence 1: NP_651012.2
• Gene: Gld2 / 42602
• FlyBaseID: FBgn0038934
• Length: 1364
• Species: Drosophila melanogaster
• Sequence 2: NP_080433.1
• Gene: Mtpap / 67440
• MGIID: 1914690
• Length: 585
• Species: Mus musculus
• Alignment Length: 683
• Identity: 143/683 - (20%)
• Similarity: 250/683 - (36%)
• Gaps: 217/683 - (31%)

  Fly   715 SFAPSVESDDSDSELSDASV-----------------ESVARDILVSCLAVATGAEEPDFSGPNL 762
            :.|.|:.|::..|.:::..:                 |...|.:|:.|              ||.
Mouse    35 TIAASIGSEEQSSVVAETGIEDKTLQKKFSEVQKERREQAQRTVLIHC--------------PNN 85

  Fly   763 VPYGDMHYLKELDKKNPPTNGYRSHRPYHQSHYAYHSQMSPRGLSCCGDMLNQHSEDLVFKLDQN 827
            :  .:..:||.|.:..|..|           |:.|.|
Mouse    86 I--NEKKFLKYLSQHGPVNN-----------HFFYES---------------------------- 109

  Fly   828 QPDGIESGKNIFLREITE--QPDNISVASNLSCSPSASSSKSVLAPMASK-SNITMPEENNDDDE 889
                      ..|..:.|  |.|:|....|.:.:|:.|:..::  |..|: .|:.:...::....
Mouse   110 ----------FGLFAVVEFCQKDSIKSLQNGTHTPTQSTEAAI--PFKSRFLNLRLKNPSSQVSG 162

  Fly   890 LPLVVHNRYWREFFGYTPADRFLLRAKFVEMRRPPKVMGCKNKWDPLSL---------SVWKKFL 945
            .|.|....                       :.||   ..|..::.||.         ::.|.|
Mouse   163 QPFVQTTN-----------------------QSPP---SSKKLFELLSYAESIEEQLNTLLKAF- 200

  Fly   946 ESQQTRHVYKIKMRLWRAIYTVAMKNYPRYGLYLVGSSISYFGSKCSDMDICMLACTNPNIDSRM 1010
              |.|....:::......|..:|...:|...:...|||::.||....|:|:.:      ::|...
Mouse   201 --QLTEENIRLRHLTCSLIEDIAAAYFPSCVIRPFGSSVNTFGKLGCDLDMFL------DLDETG 257

  Fly  1011 EAVYHLHVMKELLGRTNMFQDF----------------------------------NLIEARVPI 1041
            :...|.:.       .|.|.:|                                  .::.||.|:
Mouse   258 KLDVHKNT-------GNFFMEFQVKNVPSERIATQKILSVIGECLDNFGPGCVGVQKILNARCPL 315

  Fly  1042 LRFTDRCHKVEVDINFNNSVGIRNTHLLYCYSQLDWRVRPMALTVKQWAQYHNINNA-KNMTISS 1105
            :||:.:....:.|:..|||:.::::.|||.|..||.|||.:..:|:.||:.|::.:: ....|::
Mouse   316 VRFSHQGSGFQCDLTANNSIALKSSELLYIYGSLDSRVRALVFSVRCWARAHSLTSSIPGAWITN 380

  Fly  1106 YSLMLMVIHFLQVGASPPVLPCLHNLY----PEKFGLLQPNDFGYV-DMNEVMAPYQSDNSQTLG 1165
            :||.:|||.||| ..|||:||.|.:|.    .|...:|:.|:..:| |:|::.   .|.|::||.
Mouse   381 FSLTVMVIFFLQ-RRSPPILPTLDSLKSIADAEDRCILEGNNCTFVQDVNKIQ---PSGNTETLE 441

  Fly  1166 DLLLSFLHYYSVFDYGKYAISIRVGGVLPIEVCRAATAPKNDIHQWNELCIEEPFDQT-NTARSV 1229
            .|:..|..|:..|.:.|.:|:||.|        |....|.:     :.|.|:.||:.: |.:::|
Mouse   442 LLIKEFFEYFGNFAFNKNSINIRQG--------REQNKPDS-----SPLYIQNPFETSLNISKNV 493

  Fly  1230 YDTDTFERIKTIFVASYRRLDSTRNLSAIFEDYDGPTILMQQPSVDSEIELYEGQHHRLLPNRGS 1294
            ..:...:     ||...|  ||...|..  ||.:.|....:||...:.:.|..|..|..|
Mouse   494 SQSQLQK-----FVELAR--DSAWILEQ--EDKNQPFSSSRQPWGLAALLLPPGSGHTSL----- 544

  Fly  1295 SRSNSAIPSPRPSILMVDKATTAIWDDINNKPD 1327
            ||.....|       |.:|....:....:|.||
Mouse   545 SRKKKKKP-------MSEKVKGLLASIKSNSPD 570

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gld2	NP_651012.2	TRF4	<977..>1277	CDD:227585	88/340 (26%)
Mtpap	NP_080433.1	RL	63..131	CDD:465510	20/132 (15%)
		TRF4	177..>496	CDD:227585	87/351 (25%)
		NT_PAP_TUTase	209..347	CDD:143392	27/150 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	537..585		11/46 (24%)