Protein Alignment Gld2 and Mtpap

DIOPT Version :10

• Sequence 1: NP_651012.2
• Gene: Gld2 / 42602
• FlyBaseID: FBgn0038934
• Length: 1364
• Species: Drosophila melanogaster
• Sequence 2: NP_001386242.1
• Gene: Mtpap / 307050
• RGDID: 1310900
• Length: 584
• Species: Rattus norvegicus
• Alignment Length: 685
• Identity: 147/685 - (21%)
• Similarity: 253/685 - (36%)
• Gaps: 200/685 - (29%)

  Fly   698 ISHPNSEVDGDDNQSLASFAPSVESDDSD-----SELSDASVESVARDILVSCLAVATGAEEPDF 757
            :|.|.:.|....::...|......::|..     ||:.....|...|.:|:.|
  Rat    30 LSCPGTRVASVGSEEQPSGGAETGTEDKTLQKKFSEVQKERREQAQRTVLIHC------------ 82

  Fly   758 SGPNLVPYGDMHYLKELDKKNPPTNGYRSHRPYHQSHYAYHSQMSPRGLSCCGDMLNQHSEDLVF 822
              ||.:  .:..:||.|.:....:|           |:.|.|
  Rat    83 --PNNI--NEKKFLKYLSQHGSISN-----------HFFYES----------------------- 109

  Fly   823 KLDQNQPDGIESGKNIFLREITE--QPDNISVASNLSCSPSASSSKSVLAPMASK-SNITMPEEN 884
                           ..|..:.|  |.|:|:...|.:.:|:.|:..::  |..|: .|:.:...:
  Rat   110 ---------------FGLYAVVEFCQKDSINSLQNGTHTPTQSTEAAI--PFKSRFLNLKLKNPS 157

  Fly   885 ND---------DDELPLVVHNRYWREFFGYTPADRFLLRAKFVEMRRPPKVMGCKNKWDPLSLSV 940
            |.         |.:.|               |:.:.|.           :::......|....::
  Rat   158 NQVSGQSFVQADSQSP---------------PSSKKLF-----------ELLSYAESIDAQLTAL 196

  Fly   941 WKKFLESQQTRHVYKIKMRLWRAIYTVAMKNYPRYGLYLVGSSISYFGSKCSDMDI--------- 996
            .|.|   |.|....:::......|..:|...:|...::..|||::.||....|:|:
  Rat   197 LKAF---QLTEENVRLRHLTCSLIEDIAAAYFPSCVVWPFGSSVNTFGKLGCDLDMFLDLDETGN 258

  Fly   997 ---------CMLACTNPNIDSRMEAVYH-LHVMKELLGRTNMFQDF--------NLIEARVPILR 1043
                     .::.....|:.|...|... |.|:.|.|      .:|        .::.||.|::|
  Rat   259 LSDHKNTGNFLMEFQVKNVPSERVATQKILSVIGECL------DNFGPGCVGVQKILNARCPLVR 317

  Fly  1044 FTDRCHKVEVDINFNNSVGIRNTHLLYCYSQLDWRVRPMALTVKQWAQYHNINNA-KNMTISSYS 1107
            |:.:....:.|:..|||:.::::.|||.|..||.|||.:...|:.||:.|::.:: ....|:::|
  Rat   318 FSHQGSGFQCDLTANNSIALKSSELLYIYGSLDSRVRALVFGVRCWARAHSLTSSIPGAWITNFS 382

  Fly  1108 LMLMVIHFLQVGASPPVLPCLHNLY----PEKFGLLQPNDFGYV-DMNEVMAPYQSDNSQTLGDL 1167
            |.:|||.||| ..|||:||.|.:|.    .|...:|:.|:..:: |:|::.   .|.|::||..|
  Rat   383 LTMMVIFFLQ-RRSPPILPTLDSLKSMADAEDRCILEGNNCTFIQDINKIK---PSGNTETLELL 443

  Fly  1168 LLSFLHYYSVFDYGKYAISIRVGGVLPIEVCRAATAPKNDIHQWNELCIEEPFDQT-NTARSVYD 1231
            |..|..|:..|.:.|.:|:||.|        |....|.:     :.|.|:.||:.: |.:::|
  Rat   444 LKEFFEYFGNFAFNKNSINIRQG--------REQNKPDS-----SPLYIQNPFETSLNISKNV-- 493

  Fly  1232 TDTFERIKTIFVASYRRLDSTRNLSAIFEDYDGPTILMQ----QPSVDSEIELYEGQHHRLLPNR 1292
                         |..:|.....|:.     |...||.|    |||..|.   ..|....|||..
  Rat   494 -------------SQNQLQKFVELAR-----DSAWILEQEKKDQPSSSSH---PWGLAALLLPPG 537

  Fly  1293 GSSRSNSAIPSPRPSILMVDKATTAIWDDINNKPD 1327
            ....|.|.....:|   |.:|....:....:|.||
  Rat   538 AGQTSLSRKKKKKP---MSEKVKGLLASIKSNSPD 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gld2	NP_651012.2	TRF4	<977..>1277	CDD:227585	90/337 (27%)
Mtpap	NP_001386242.1	RL	63..131	CDD:465510	21/132 (16%)
		TRF4	184..>496	CDD:227585	89/352 (25%)
		NT_PAP_TUTase	209..347	CDD:143392	30/143 (21%)