Protein Alignment Gld2 and Tut4

DIOPT Version :10

• Sequence 1: NP_651012.2
• Gene: Gld2 / 42602
• FlyBaseID: FBgn0038934
• Length: 1364
• Species: Drosophila melanogaster
• Sequence 2: XP_036019916.1
• Gene: Tut4 / 230594
• MGIID: 2445126
• Length: 1660
• Species: Mus musculus
• Alignment Length: 600
• Identity: 146/600 - (24%)
• Similarity: 232/600 - (38%)
• Gaps: 184/600 - (30%)

  Fly   685 KQDTSELDTHSCLISHPNSEVD-------GDDNQSLASFAPSVESDDSDSELSDAS-------VE 735
            |.|.:|..:..|::.:.:..|:       |.|:.||     |..|..||.:...|.       .|
Mouse   784 KHDETEFTSQRCIVDNDSLLVNELGLANHGQDSSSL-----STASGGSDLKQKSAEKQGDLTPSE 843

  Fly   736 SVARDILVSCLAVAT--GAEEPDFSGPNLVPYGDMHYLKELDKKNPPTNGYRSHRPYHQSHYAYH 798
            :..:..|..|:.:.|  |||.   :|.:.                      ||:.....||....
Mouse   844 TSLKKELSQCICIGTPDGAES---AGTDC----------------------RSNLEMDSSHQIVC 883

  Fly   799 SQMSPRGLSC-----CGDML---NQHSEDLVFKLDQNQPDGIESGKNIFLREITEQPDNISVASN 855
            :.:|....:|     ..|::   |..|::|.:..|:..   :.|||          |..|
Mouse   884 NNVSATSCNCKATEVTSDLVDEDNLPSQELYYVFDKFI---LTSGK----------PPTI----- 930

  Fly   856 LSCSPSASSSKSVLAPMASKSNITMPEENNDDDELPLVVHNRYWREFFGYTPADRFLLRAKFVEM 920
             .||         :......|....||:....|..||......:||...
Mouse   931 -VCS---------ICKKDGHSKNDCPEDFRKIDLKPLPPMTNRFREILD---------------- 969

  Fly   921 RRPPKVMGCKNKWDPLS------------LSVWKKFLESQQTRHVYKIKMRLWRAIYTVAMKNYP 973
                  :.||..:|.||            |...:||::.:     |..|.|
Mouse   970 ------LVCKRCFDELSPPCSEQHNREQILIGLEKFIQKE-----YDEKAR-------------- 1009

  Fly   974 RYGLYLVGSSISYFGSKCSDMDICMLACTNPNID--SRMEAVYHL-HVMKELLGRTNMFQDFNLI 1035
               |.|.|||.:.||.:.||:||||....:.|.:  :..|.:.:| .::|...|..|:..   :.
Mouse  1010 ---LCLFGSSKNGFGFRDSDLDICMTLEGHENAEKLNCKEIIENLAKILKRHPGLRNILP---IT 1068

  Fly  1036 EARVPILRFTDRCHKVEVDINFNNSVGIRNTHLLYCYSQLDWRVRPMALTVKQWAQYHNINNAKN 1100
            .|:|||::|..|...:|.||:..|::...||.:|..|:.:|.||:.:..|:|.:|:..:|.:|..
Mouse  1069 TAKVPIVKFEHRRSGLEGDISLYNTLAQHNTRMLATYAAIDPRVQYLGYTMKVFAKRCDIGDASR 1133

  Fly  1101 MTISSYSLMLMVIHFLQVGASPPVLPCLHNLYPEKFGL--LQPNDF----------------GYV 1147
            .::|||:.:|||::||| ...|||:|.|.    |:..|  :.||:.                .:.
Mouse  1134 GSLSSYAYILMVLYFLQ-QRKPPVIPVLQ----EQINLEDIIPNEIFDGKQIPQRMVDGWNAFFF 1193

  Fly  1148 DMNEVM---APYQSDNSQTLGDLLLSFLHYYS-VFDYGKYAISIRVGGVLPIEVCRAATAPKNDI 1208
            |..|.:   .|....|:::||:|.|..|.:|: .||:.:|.||||...:|       .|..|
Mouse  1194 DKTEELKKRLPSLGKNTESLGELWLGLLRFYTEEFDFKEYVISIRQKKLL-------TTFEK--- 1248

  Fly  1209 HQWNELC--IEEPFD 1221
             ||...|  ||:|||
Mouse  1249 -QWTSKCIAIEDPFD 1262

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gld2	NP_651012.2	TRF4	<977..>1277	CDD:227585	86/271 (32%)
Tut4	XP_036019916.1	rad2	<2..>366	CDD:273166
		TUTase	274..491	CDD:465974
		PAP_assoc	648..697	CDD:427532
		TRF4	946..>1289	CDD:227585	104/379 (27%)
		NT_PAP_TUTase	988..1106	CDD:143392	38/142 (27%)
		AIR1	<1304..>1393	CDD:227414