Protein Alignment Gld2 and gldr-2

DIOPT Version :10

• Sequence 1: NP_651012.2
• Gene: Gld2 / 42602
• FlyBaseID: FBgn0038934
• Length: 1364
• Species: Drosophila melanogaster
• Sequence 2: NP_001021434.1
• Gene: gldr-2 / 173373
• WormBaseID: WBGene00009284
• Length: 808
• Species: Caenorhabditis elegans
• Alignment Length: 862
• Identity: 199/862 - (23%)
• Similarity: 330/862 - (38%)
• Gaps: 246/862 - (28%)

  Fly   527 QPPQQSTSTVRR------------TSKFQGSNAYQAHTAAGRQQSRFYQSRHMDGYVFQSGHYMV 579
            :||:  .:.|:|            .||..|.:|..|..:||.....|::....:|:   ....:.
 Worm    49 EPPE--NADVKRFISFATIPACCLHSKGTGQDAQSADESAGYAMLDFFKLYISNGF---RSKLLN 108

  Fly   580 YAAGAPPVGLRPGKSPVSEATGAPPGAAAATAAAATAVAATAAAAEGGGA--------AEGGGAA 636
            .|:......|.|...|:.|...|...|...:.:..|....|.||...|..        .:..|..
 Worm   109 CASDEEVKELIPQVQPLFEQFKAAIAADFLSISRCTQFELTPAARARGKELKKRVLTNLKNAGVG 173

  Fly   637 AAPVTASSATLEGEQPLDSDFDQRQEFADLGLDP--ANGGFSSD-------------------LE 680
            ...||... ||:.:     |.|..::..:..:||  |.|..|||                   .|
 Worm   174 YTTVTPKK-TLKND-----DDDVEEDVPNETVDPSDAPGSSSSDDIVIVREVASEASPKLRKMRE 232

  Fly   681 PNGIKQDTSE--------------LDTHSCL-----ISHPNSEV---DGDDNQSLASF--APSVE 721
            .:|.|:...|              ||:.:..     :.|..:||   ..:.||.:..:  |.|.|
 Worm   233 MDGAKKKLIEEATMRLGENRRSPSLDSDTYFGECQQLLHGPTEVYCARPESNQFVQQYEEANSTE 297

  Fly   722 -SDDSDSEL-----SDASVESVARDILVSCLAVATGAEEPDFSGPNLVPYGDMHYLKELDKKNPP 780
             |:|.|.|.     :...:|....|::|..:..::|..                     |||
 Worm   298 ASEDEDKEAVPMKRARVDIEEDDDDVIVLNMTTSSGVS---------------------DKK--- 338

  Fly   781 TNGYRSHRPYHQSHYAYHSQMSPRGLSCCGDMLNQHSE--DLVFKLDQNQPDGIESGKNIFLREI 843
                                          |:.....|  |:|.:.|.|.    |..|...|.|:
 Worm   339 ------------------------------DVSGSEDEIGDIVDEWDAND----EEEKTDELEEL 369

  Fly   844 TEQPDNISVASNLSCSPSASSSKSVLAPMASKSNITMPEENNDDDELPLVVHNRYWREFFGYTPA 908
              :.|:|.:   :......:..:.|.:.:.|   :..|..::|:::    ::|.:.....
 Worm   370 --EDDDIQI---IEAGDQGNGVEEVSSTVIS---VETPNSSSDENK----IYNGHQTHQI----- 417

  Fly   909 DRFLLRAKFVEMRRPP--------------KVMGCKNKW------------DPLSLSVWKKFLES 947
                    |.|:|:.|              ::.|...|:            ..||...|..:|.:
 Worm   418 --------FREVRQLPVNYQARTIGVVLNERIAGSVEKFVNSITKKSFNSVKQLSKLAWDHYLGN 474

  Fly   948 QQTRHVYKIKMRLWRAIYTVAMKNYP--RYGLYLVGSSISYFGSKCSDMDICMLACTN------- 1003
            .|...|:..||...:.:::...|.:|  ...|...||:::..||..||||:|:...||
 Worm   475 AQPDFVFLKKMEARQKLFSEIKKLFPDTEIKLQTTGSTVNGCGSFNSDMDLCLCFPTNGYKGQVC 539

  Fly  1004 --------------PNIDSRMEAVYHLHVMKELLGRTNMFQDFNLIEARVPILR--FTDRCHKVE 1052
                          ..||......:..|.:|:::      :...|:.|:|||::  .......:|
 Worm   540 DDFHCDRNYSTKILRKIDKAFRRSHWSHPLKKII------KTMQLVPAKVPIVKMILNGEFDGIE 598

  Fly  1053 VDINFNNSVGIRNTHLLYCYSQLDWRVRPMALTVKQWAQYHNINNAKNMTISSYSLMLMVIHFLQ 1117
            ||||.||..||.|:||::.||..|.|:..:||.||.||....||||::..::||:.:|:|:|:||
 Worm   599 VDINVNNIAGIYNSHLIHYYSLTDARLPALALLVKHWAMVTGINNAQDGFLNSYTTILLVVHYLQ 663

  Fly  1118 VGASPPVLPCLHNLYPEKFGLLQPNDFGYVDMNEVM--------APYQSDNSQTLGDLLLSFLHY 1174
            .|.:|.|:|.|..|:|.||....|       :||::        .|....|:.:||:||:.|..|
 Worm   664 CGVTPAVIPNLQYLFPHKFDRKLP-------LNELLLFGDIADKLPTSPPNTWSLGELLIGFFQY 721

  Fly  1175 YSVFDYGKYAISIRVGGVLPIEVCRAATAPKNDIHQWNELCIEEPFDQTNTARSVYDTDTFERIK 1239
            |:.||:..:..|||.|.|:|.|     ..|::.|:  :.:.:|||||..||||:|.|....:.||
 Worm   722 YNEFDFTNFGFSIRSGQVIPRE-----NLPRDLIN--SPIVVEEPFDAINTARTVRDVSHMKSIK 779

  Fly  1240 TIFVASYRRLDSTRNLS 1256
            :.|..:.:.:.|.:|.:
 Worm   780 SAFRCAVQIISSNKNFT 796

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gld2	NP_651012.2	TRF4	<977..>1277	CDD:227585	102/311 (33%)
gldr-2	NP_001021434.1	TRF4	483..>799	CDD:227585	106/334 (32%)