Protein Alignment Gld2 and gld-2

DIOPT Version :10

• Sequence 1: NP_651012.2
• Gene: Gld2 / 42602
• FlyBaseID: FBgn0038934
• Length: 1364
• Species: Drosophila melanogaster
• Sequence 2: NP_491842.2
• Gene: gld-2 / 172338
• WormBaseID: WBGene00001596
• Length: 1113
• Species: Caenorhabditis elegans
• Alignment Length: 1108
• Identity: 277/1108 - (25%)
• Similarity: 401/1108 - (36%)
• Gaps: 325/1108 - (29%)

  Fly   425 SSDQNVATKRNHQGAATQNNHRNRHNAKKGGK--NSVGKELTSNSSESLSNSSSKSQLNKRPSSS 487
            |.|.|.....||.|     |.|..:|.::||:  |..|......:.|...|.....:.::|..:.
 Worm    60 SRDGNTGYYNNHSG-----NKRQTYNNQRGGRSYNHRGNSNYQQNGEYSGNQGCVPKYHQRNQNY 119

  Fly   488 SSISPIKHPHRNYRNRMRYTATEPTEQKAATTTVPISNY-----QPPQQ---STSTVRRTS---- 540
            ..:.|            :|:..:|.::....:|.....|     .||..   |:||...||
 Worm   120 PQLQP------------KYSYFQPHQRPIFNSTQGYGTYSVRRSSPPSPSALSSSTANSTSNRAP 172

  Fly   541 ----------------KFQGSNAYQAHTAAGRQQSRFYQSRHMDGYVFQSGHYMVYAAGAPPVGL 589
                            ..|||:..|.|.    .:...|:|                 ||..|.|.
 Worm   173 TQPPILLRHAEPASDKNHQGSDHEQNHD----PKIHLYRS-----------------AGTAPGGY 216

  Fly   590 RPGKSPVSEATGAPPGAAAATAAAATAVAATAAAAEGGGAAEGGGAAAAPVTASSATLEGEQPLD 654
            ....||..:....||.                                   |.||:....||...
 Worm   217 TQCPSPYKQPPPQPPS-----------------------------------TPSSSDKRIEQQQA 246

  Fly   655 SDFDQRQEFAD----LGLDPANGGFSSDLEPNGIKQDTSELDTHSCLISHPNSEVDGDDNQSLAS 715
            .|:..|.:...    .|.||.         |..|     ||...:...:.|...|..:..::::|
 Worm   247 EDWPTRFQHPPPQFRRGQDPM---------PASI-----ELQHKTANQTMPVDIVQTNQQKTVSS 297

  Fly   716 FAPSVESDDSDSELSDASVES----VARDILVSCLAVATGAEEPDFSGPNLVPYGD------MHY 770
            :..:.:...|.|||...||::    .|.:.:.|.|...:...:.....|.:....:      |..
 Worm   298 YERAAQFRASASELPTDSVDAKHPCFANERMQSALIGISPQLKTQQQSPGIPIQNEAEASAVMKA 362

  Fly   771 LKELDKKNPPTNGYRSHRPYHQSHYAYHSQMSPRGLSCCGDM--LNQHSEDL------------- 820
            ::.....|.|   ..||..|:...|...:||.|..   .||.  |||.:.:|
 Worm   363 MRSFQFHNWP---QMSHGSYYPMPYHLENQMRPMK---SGDQLPLNQQNHNLSGFPAFVGKSSLV 421

  Fly   821 --------------------VFKLDQNQPDGIESGKNI--------------------FLREITE 845
                                :.||| ::..|.:..|.|                    .|.|:..
 Worm   422 GSSLNTRNSSEADPEEMPRIMEKLD-DEVTGADHDKTIDENRRRIHKSQEPRIGTEEKALNELPR 485

  Fly   846 QPDNISVASNLSCSPSASSSKSVLAPMASKSNIT--MPEENNDDDELPLVVHNRYWREFFGYTPA 908
            :.:.    .|.|||..:|.|:|.......:|.:|  :|.:|           .|..|.|...:|.
 Worm   486 KANR----RNSSCSSISSVSESSSPSALDESTLTKILPTDN-----------FRGGRGFASPSPP 535

  Fly   909 DRFLLRAKFVEMRRPPKVMGCKNKWDPLSLSVWKKFLESQQTRHVYKIKMRLWRAIYTVAMKNYP 973
            ...|...              .::.|.||..:|....:..||..:.:.|:.|...:||.....:|
 Worm   536 TSLLSEP--------------LSRMDVLSEKIWDYHNKVSQTDEMLQRKLHLRDMLYTAISPVFP 586

  Fly   974 RYGLYLVGSSISYFGSKCSDMDICMLACTNPNIDSRMEAVYHLHVMKELLGRTNMFQDFNLIEAR 1038
            ..|||:||||::.||:..||||:|:: .||.::|.:.:||..|:::...|......:...||.|:
 Worm   587 LSGLYVVGSSLNGFGNNSSDMDLCLM-ITNKDLDQKNDAVVVLNLILSTLQYEKFVESQKLILAK 650

  Fly  1039 VPILR--FTDRCHKVEVDINFNNSVGIRNTHLLYCYSQLDWRVRPMALTVKQWAQYHNINNAKNM 1101
            |||||  |......:.||:|.||||.|||||||..||..||||||:...||:||:...||:|...
 Worm   651 VPILRINFAAPFDDITVDLNANNSVAIRNTHLLCYYSSYDWRVRPLVSVVKEWAKRKGINDANKS 715

  Fly  1102 TISSYSLMLMVIHFLQVGASPPVLPCLHNLYPEKFGLLQPNDFGYVDMNEVMA--PYQSDNSQ-- 1162
            :.:||||:||||||||.|.: .|||.|...||.:|.    |......:|..||  ....|..|
 Worm   716 SFTSYSLVLMVIHFLQCGPT-KVLPNLQQSYPNRFS----NKVDVRTLNVTMALEEVADDIDQSL 775

  Fly  1163 ----TLGDLLLSFLHYY-SVFDYGKYAISIRVGGVLPIEVCRAATAPKNDIH------------- 1209
                |||:||:.||.|| :.|:|.:.|||||.|.    .|.|||.|.:..||
 Worm   776 SEKTTLGELLIGFLDYYANEFNYDRDAISIRQGR----RVERAALAVRPKIHSNSEGDKETPPPS 836

  Fly  1210 ------------------------------QWNELCIEEPFDQTNTARSVYDTDTFERIKTIFVA 1244
                                          ||..:||||||..:|||.|:||...||.||..|..
 Worm   837 SSASTSSIHNGGTPGIPMHHSISNPHFWRSQWRCVCIEEPFTNSNTAHSIYDEMVFEAIKKAFRE 901

  Fly  1245 SYRRLDSTRNLSAIFE------------------DYDGPTILMQQPS--------VDSEIELYEG 1283
            ::..|....:|..:.|                  .|:|...|.|||:        |.:.|.:..|
 Worm   902 AHGELQHNHDLDKLMECEPIKASTTNTGAAVFAATYEGERPLAQQPNTIACASLRVLNSIPVSSG 966

  Fly  1284 ---QHHRLLPNRGSSRSNSAIPSPRPSILMVDKATTAIWDDINNKPDHPVLSHSNNYDATNECTG 1345
               .|::...|:..||..      ||......:.......:.||:..|......||..::|  .|
 Worm   967 PGHYHYQQQSNQNLSRPQ------RPGSNQGYQMNNNRGFNGNNQQQHQNRRSFNNQSSSN--PG 1023

  Fly  1346 NGS 1348
            |||
 Worm  1024 NGS 1026

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Gld2	NP_651012.2	TRF4	<977..>1277	CDD:227585	137/379 (36%)
gld-2	NP_491842.2	TRF4	532..>812	CDD:227585	115/303 (38%)