DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SKIP and Samd5

DIOPT Version :9

Sequence 1:	NP_001262827.1	Gene:	SKIP / 42601	FlyBaseID:	FBgn0051163	Length:	1080	Species:	Drosophila melanogaster
Sequence 2:	XP_017169459.1	Gene:	Samd5 / 320825	MGIID:	2444815	Length:	182	Species:	Mus musculus

Alignment Length:	159	Identity:	66/159 - (41%)
Similarity:	90/159 - (56%)	Gaps:	38/159 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 SNIVCEWLRALGLAQYAESFLDNGYDDLEICKQVGDPDLDAIGVENPAHRHKLLKSIRSLREK-- 66
            :|||.|||:||.|.||||||:||||||||:|||:||||||||||..||||.::|:::..|||:
Mouse     3 TNIVYEWLKALQLPQYAESFVDNGYDDLEVCKQIGDPDLDAIGVLAPAHRRRILEAVHRLREQDA 67

  Fly    67 GAASVYFML-------------------------------NDPNSLSG---SMEILCETPPNNEL 97
            .||.:||.|                               .||....|   |.|::  :.|..:|
Mouse    68 AAAGLYFTLEPQPVPPAPLVEAVPPGRRGEPCGSSAQGTRGDPRGQPGAPCSRELV--SYPKLKL 130

  Fly    98 ELVLREQLETDGVRLTAHPYSTPPSSCLS 126
            ::::|::|..||:.|:..|||...|...|
Mouse   131 KIMIRDKLVRDGIHLSKPPYSRKVSGISS 159

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SKIP	NP_001262827.1	SAM_Samd5	4..65	CDD:188926	42/60 (70%)
		SAM	7..65	CDD:197735	40/57 (70%)
		SH3	657..710	CDD:302595
		SAM	738..801	CDD:197735
		SAM_superfamily	742..800	CDD:301707
Samd5	XP_017169459.1	SAM_Samd5	2..64	CDD:188926	42/60 (70%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	96	1.000	Domainoid score	I7307
eggNOG	1	0.900	-	-		E1_KOG4384
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0006313
OrthoInspector	1	1.000	-	-		otm42795
orthoMCL	1	0.900	-	-		OOG6_108165
Panther	1	1.100	-	-	LDO	PTHR12301
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5033
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	8	7.840