DRSC/TRiP Functional Genomics Resources

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Protein Alignment how and khdrbs2

DIOPT Version :9

Sequence 1:NP_001262822.1 Gene:how / 42596 FlyBaseID:FBgn0264491 Length:418 Species:Drosophila melanogaster
Sequence 2:NP_001070758.1 Gene:khdrbs2 / 768147 ZFINID:ZDB-GENE-061013-497 Length:346 Species:Danio rerio


Alignment Length:381 Identity:112/381 - (29%)
Similarity:175/381 - (45%) Gaps:97/381 - (25%)


- Green bases have known domain annotations that are detailed below.


  Fly    78 YLAQLLKDRKQLAAFPNVFTHVERLLDEEIARVRASLFQINGVKKEPLTLPEPEGSVVTMNEKVY 142
            ||.:|:.:::.|.|   .|.|..|||.|||.:......:.:|..|:.|.:...:.  :.::|:|.
Zfish     6 YLPELVAEKESLDA---SFVHAMRLLAEEIEKFEGDELRKDGEVKKYLDIISNKN--IKLSERVL 65

  Fly   143 VPVREHPDFNFVGRILGPRGMTAKQLEQETGCKIMVRGKGSMRDKKKEDANR--GKPNWEHLSDD 205
            :||:::|.|||||::|||||.:.|:|::|||.|:.:.||||||||.||:..|  |:..:.|||:|
Zfish    66 IPVQQYPKFNFVGKLLGPRGNSMKRLQEETGAKMSILGKGSMRDKGKEEELRKSGEAKYAHLSND 130

  Fly   206 LHVLITVEDTENRATVKLAQAVAEVQKLLVPQAEGEDELKKRQLMELAIINGTYRDTTAKSVAAF 270
            |||||.|......|..:::.|:.|::|.|||  :..||:::.||.||:.:||:            
Zfish   131 LHVLIEVFAPPGEAYSRMSHALEEIKKFLVP--DYNDEIRQEQLRELSYLNGS------------ 181

  Fly   271 SCVGSASYLYPAVCDEEWRRLVAASDSRLLTSTGLP---GLAAQIRAP---AAAPLGAPLILNPR 329
                          |:..|...|......||||..|   |.||....|   ||||.|.   ::.|
Zfish   182 --------------DDPSRGRSARGRGLRLTSTASPRGRGSAAPPAPPGRGAAAPRGT---VSSR 229

  Fly   330 MTVPTTAASILSAQAAPTA---------------AFDQTGHGMIF-APYDYANYAALAGNPLLTE 378
            .:|||.|..:.:.:...||               .::..|:...: ..||..:|.:...|     
Zfish   230 TSVPTPARGVSAPRTRGTAGTPGYRAPSLQATHKTYEDYGYDDGYDGEYDDQSYESYDDN----- 289

  Fly   379 YADHSGAIKQ------------------------------QRRLATN--REHPYQR 402
            |::.|.::.:                              ..||...  |:|||.|
Zfish   290 YSNQSKSVSEYYEYGHGNNDENYNNYEEDWISSRPNLKAPASRLTRGGYRDHPYGR 345

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
howNP_001262822.1 STAR_dimer 75..123 CDD:293152 14/44 (32%)
SF1_like-KH 139..260 CDD:239088 58/122 (48%)
khdrbs2NP_001070758.1 Qua1 6..57 CDD:292891 16/53 (30%)
SF1_like-KH 61..180 CDD:239088 56/120 (47%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 175..292 33/150 (22%)
Sam68-YY <281..>306 CDD:293176 4/29 (14%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5176
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
32.810

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