Protein Alignment how and SF1

DIOPT Version :10

• Sequence 1: NP_001262822.1
• Gene: how / 42596
• FlyBaseID: FBgn0264491
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_524654.2
• Gene: SF1 / 43912
• FlyBaseID: FBgn0025571
• Length: 787
• Species: Drosophila melanogaster
• Alignment Length: 465
• Identity: 106/465 - (22%)
• Similarity: 183/465 - (39%)
• Gaps: 151/465 - (32%)

  Fly    30 AQQQQAQAQAQAQAQAQQQQQAPQVVVPMTPQHLTPQQQQQSTQSIADYLAQLLKDRKQLAAFPN 94
            |||:....|.|.: :..::.:...:.:...|:..:|     |.:.|.....:.|..|:
  Fly   302 AQQEAYLVQFQIE-EISRKLRTGDLGITQNPEERSP-----SPEPIYSSDGKRLNTRE------- 353

  Fly    95 VFTHVERLLDEEIARVRASLFQINGVKKEPLTLPEPEGSVVTMNEKVYVPVREHPDFNFVGRILG 159
             |.:.:| |:|:..::...:..:|...|.|.....|   |..:::||.:|..:|||.||||.::|
  Fly   354 -FRYRKR-LEEQRHQLIVKMQTVNPEFKPPADYKPP---VTRVSDKVLIPQEQHPDINFVGLLIG 413

  Fly   160 PRGMTAKQLEQETGCKIMVRGKGSMRDKKKEDANRGKPNWEHL---SDDLHVLITVEDTENRATV 221
            |||.|.|.:|::||.||::|||||:::.|.     |:.:.:.|   .:.||..||..:.|  |..
  Fly   414 PRGNTLKAMEKDTGAKIIIRGKGSVKEGKV-----GRKDGQPLPGEDEPLHAFITAPNPE--AVR 471

  Fly   222 KLAQAVAEVQKLLVPQAEGEDELKKRQLMELAIINGTYRDTTAKSVAAFSCVGSASYLYPAVCDE 286
            |....:.:|.:..:...||.::|::.||.|||.:|||.|:   ..:...:| ||..:       :
  Fly   472 KAVDKIKDVIRQGIEVPEGHNDLRRMQLRELAQLNGTLRE---NDIQRCTC-GSTDH-------K 525

  Fly   287 EWRRLVAASDSRLLTST-----------------------GLPGLA-----AQI----------- 312
            .|:    ..|..::|:|                       |:||:|     |:|
  Fly   526 SWQ----CPDKPIITNTIVCTSCGGTGHLTKDCRNKRPGSGVPGMACEDSQAKIDEEYMSLMAEL 586

  Fly   313 -RAP----AAAPLGAPLILNPRM---------TVPTTAASILSAQAAPTAA-------------- 349
             ..|    |:|....|....|::         ..|:...:|   |:.|:::
  Fly   587 GEGPPPPSASAKTDPPASNGPQLHRASYSIFDKKPSQMQAI---QSPPSSSSRDHQRDLGGWGAA 648

  Fly   350 -------------FDQTGHGMIFAPYDYANYAALAGNPLLTEYADHSGAIKQQRRLATNREHPYQ 401
                         .||.|||:          ||:          ||..::..:..:|.     |.
  Fly   649 AHEHGMGMEHGMGLDQHGHGL----------AAM----------DHGMSLGMEHAMAA-----YV 688

  Fly   402 RATVGVPAKP 411
            .|..|..|.|
  Fly   689 PAPPGTQAPP 698

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
how	NP_001262822.1	STAR_dimer	75..122	CDD:435414	8/46 (17%)
		KH-I_HOW	132..236	CDD:411894	38/106 (36%)
SF1	NP_524654.2	MSL5	253..512	CDD:227503	69/237 (29%)
		PTZ00368	<519..>568	CDD:173561	10/60 (17%)