Protein Alignment how and qki2

DIOPT Version :10

• Sequence 1: NP_001262822.1
• Gene: how / 42596
• FlyBaseID: FBgn0264491
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: XP_021335713.1
• Gene: qki2 / 393815
• ZFINID: ZDB-GENE-040426-1462
• Length: 341
• Species: Danio rerio
• Alignment Length: 350
• Identity: 176/350 - (50%)
• Similarity: 221/350 - (63%)
• Gaps: 39/350 - (11%)

  Fly    67 QQQQSTQSIADYLAQLLKDRKQLAAFPN---VFTHVERLLDEEIARVRASLFQ--ING-VKKEPL 125
            :.::..:...|||.||:.|:|.:::.||   :|.|:||||||||.|||..::.  :|| ..|...
Zfish     6 ETKEKPKPTPDYLMQLMNDKKLMSSLPNFCGIFNHLERLLDEEIGRVRKDMYNDTLNGSTDKRTS 70

  Fly   126 TLPEPEGSVVTMNEKVYVPVREHPDFNFVGRILGPRGMTAKQLEQETGCKIMVRGKGSMRDKKKE 190
            .||:..|.:..:.||:||||:|:||||||||||||||:||||||.||||||||||||||||||||
Zfish    71 ELPDAVGPIAQLQEKLYVPVKEYPDFNFVGRILGPRGLTAKQLEAETGCKIMVRGKGSMRDKKKE 135

  Fly   191 DANRGKPNWEHLSDDLHVLITVEDTENRATVKLAQAVAEVQKLLVPQAEGEDELKKRQLMELAII 255
            :.||||||||||::||||||||||::|||.:||.:||.||:|||||.|||||.|||.|||||||:
Zfish   136 EQNRGKPNWEHLNEDLHVLITVEDSQNRAEIKLKRAVEEVKKLLVPAAEGEDSLKKMQLMELAIL 200

  Fly   256 NGTYRDTTAKSVA-AFSCVGSASYLYPAVCDEEWRRLVAASDSRLLT--STGLPGLAAQIRAPAA 317
            ||||||...||.| |||...:                  |...|::|  :..:|..|.:..|| .
Zfish   201 NGTYRDANIKSPALAFSLAAT------------------AQAPRIMTGPTPVMPNAALRTPAP-T 246

  Fly   318 APLGAPLILNPRMTVPTTAASILSAQAAPTAA-FDQTGH-GMIFAPYDYANYAALAGNPLLTEYA 380
            ||...|||...:     |:|.:.:....|||. ..||.. |:|:|||||. ||......:|....
Zfish   247 APTLMPLIRQIQ-----TSALMPTGTPHPTATLLPQTPESGIIYAPYDYP-YALAPATSILEYPI 305

  Fly   381 DHS---GAIKQQRRLATNREHPYQR 402
            |.|   ||:..:.|....|.|||||
Zfish   306 DSSGVLGAVTTKVRRQDMRVHPYQR 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
how	NP_001262822.1	STAR_dimer	75..122	CDD:435414	24/52 (46%)
		KH-I_HOW	132..236	CDD:411894	80/103 (78%)
qki2	XP_021335713.1	STAR_dimer	10..64	CDD:435414	23/53 (43%)
		KH-I_Hqk	81..183	CDD:411893	81/101 (80%)
		PRK04654	139..299	CDD:135173	88/184 (48%)
		Quaking_NLS	312..341	CDD:435421	8/18 (44%)