Protein Alignment how and Y57G11C.36

DIOPT Version :9

• Sequence 1: NP_001262822.1
• Gene: how / 42596
• FlyBaseID: FBgn0264491
• Length: 418
• Species: Drosophila melanogaster
• Sequence 2: NP_001379320.1
• Gene: Y57G11C.36 / 259844
• WormBaseID: WBGene00013325
• Length: 380
• Species: Caenorhabditis elegans
• Alignment Length: 248
• Identity: 79/248 - (31%)
• Similarity: 124/248 - (50%)
• Gaps: 33/248 - (13%)

  Fly    45 AQQQQQAPQVVVP----------MTPQHLTPQQQQQSTQSIADYLAQLLKDRKQLAAFPN-VFTH 98
            |::.|.:..:..|          .|..| :.|:..::...:..|:..|..::.|||.:.: .|.|
 Worm    18 AEKHQHSSLLTPPPSDDSQKSLKSTSNH-SDQEMSKNLHDVEAYIDALKGEKHQLAQYSSGGFNH 81

  Fly    99 VERLLDEEIARVRASLFQINGVKKEPLTLPEPEGSVVTMNEKVYVPVREHPDFNFVGRILGPRGM 163
            |..|:|:||.:|..:.....|.:.      ..:||::|  |.:.|||.:.||:|||||:|||||.
 Worm    82 VFNLIDKEIQKVGGNDAHDGGSQM------SGDGSMLT--ETIMVPVEKFPDYNFVGRLLGPRGT 138

  Fly   164 TAKQLEQETGCKIMVRGKGSMRDKKKEDANRGKPNWEHLSDDLHVLITVEDTENRATVKLAQAVA 228
            ||||||..|||:|.:.|      :.|.|.:...|  :..:..|.|.|:|.....:|...|...|.
 Worm   139 TAKQLEVTTGCRITILG------RTKRDGSSSNP--DVTTGPLRVQISVPADMPQAAKLLKGGVG 195

  Fly   229 EVQKLLVPQAEGEDELKKRQLMELAIINGTYRDTTAKSVAAFSCVGSASYLYP 281
            .:|.:|....:|.||||::||:.||.:||||:..     .:.:..||..|.:|
 Worm   196 HIQAILDVPTDGNDELKRQQLLILANMNGTYQPR-----GSATSPGSGDYGHP 243

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
how	NP_001262822.1	STAR_dimer	75..123	CDD:293152	14/48 (29%)
		SF1_like-KH	139..260	CDD:239088	51/120 (43%)
Y57G11C.36	NP_001379320.1	MSL5	<85..225	CDD:227503	58/155 (37%)
		KH-I	112..>162	CDD:412160	30/57 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S1833
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1565749at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.870