DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment how and K07H8.9

DIOPT Version :9

Sequence 1:	NP_001262822.1	Gene:	how / 42596	FlyBaseID:	FBgn0264491	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_501390.1	Gene:	K07H8.9 / 177620	WormBaseID:	WBGene00019509	Length:	254	Species:	Caenorhabditis elegans

Alignment Length:	244	Identity:	79/244 - (32%)
Similarity:	126/244 - (51%)	Gaps:	31/244 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    48 QQQAPQVV--VPMTPQHLTPQQQQQSTQSIADYLAQLLKDRKQLAAF--PNVFTHVERLLDEEIA 108
            ||:..|::  ....|:.:...::......:..|...||.::.:|..:  .|...|   |:||||.
Worm    12 QQKFMQILSDYERDPKSIQIHEESDQMDVVISYFKLLLAEKSRLLQYGQANFSVH---LIDEEIG 73

  Fly   109 RV------RASLFQINGVKKEPLTLPE-------------PEGSVVTMNEKVYVPVREHPDFNFV 154
            |:      .|.:..:....:|.|...:             .:...||:.|.:.:||..:|.:||:
Worm    74 RLFMAPISMADIGILEECGREALRFTDLGAMFSDSDDSMHSDEDEVTLTESIRIPVETYPTYNFI 138

  Fly   155 GRILGPRGMTAKQLEQETGCKIMVRGKGSMRDKKKEDA---NRGKPNWEHLSDDLHVLITVEDTE 216
            |||:||||.||||||::|||:||:||..|  :|...:|   ..|..:.:.:...|.|::......
Worm   139 GRIIGPRGTTAKQLEKDTGCRIMIRGNHS--NKMYGNALHKTHGDGSQDAIDLPLRVIVETSGPR 201

  Fly   217 NRATVKLAQAVAEVQKLLVPQAEGEDELKKRQLMELAIINGTYRDTTAK 265
            ..||.::..|:..||.||||..:|.||||:|||:||||:|||||.:.::
Worm   202 REATARITAALETVQVLLVPPPDGRDELKRRQLVELAIMNGTYRPSCSR 250

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
how	NP_001262822.1	STAR_dimer	75..123	CDD:293152	13/55 (24%)
how	NP_001262822.1	SF1_like-KH	139..260	CDD:239088	56/123 (46%)
K07H8.9	NP_501390.1	SF1_like-KH	122..245	CDD:239088	56/124 (45%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5176
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1565749at2759
OrthoFinder	1	1.000	-	-		FOG0001806
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11208
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	7	6.880