Protein Alignment pit and RRP3

DIOPT Version :10

• Sequence 1: NP_524446.3
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_011932.2
• Gene: RRP3 / 856462
• SGDID: S000001107
• Length: 501
• Species: Saccharomyces cerevisiae
• Alignment Length: 561
• Identity: 171/561 - (30%)
• Similarity: 282/561 - (50%)
• Gaps: 94/561 - (16%)

  Fly    75 KKKQQKQPPKKQQIQVANSDSESDDDEQEDEADEDSDLDEVAEVDEEDVDSGSEDDDQQEDEDEE 139
            |:|::|          ||.:..|..::...:|     |:...::.|.:.:.|||       .|.|
Yeast     6 KRKEKK----------ANDELTSLAEKIRAKA-----LENQKKLIEAEKEGGSE-------SDSE 48

  Fly   140 EPVPAKKTKLLPNKSKAQNGKPAKDDEPFTVESSLAALDYRDSDDRSFASLKGAVSEATL----- 199
            |...|:|.|:|.:|||                |:::..:...::|.||.|.    ||..|
Yeast    49 EDATAEKKKVLKSKSK----------------STVSTQNENTNEDESFESF----SELNLVPELI 93

  Fly   200 RAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVELINKLRFMPRNGTGVII 264
            :|.|.:.:::.|.||||::.|.|:|.|::|.||||||||.||.||   ::|:| :..:......|
Yeast    94 QACKNLNYSKPTPIQSKAIPPALEGHDIIGLAQTGSGKTAAFAIP---ILNRL-WHDQEPYYACI 154

  Fly   265 ISPTRELSMQ---TFGVLKELMAHHHHTYGL----VMGGSNRQVESEKLGKGINILVATPGRLLD 322
            ::|||||:.|   ||..|..||       |:    ::||.|...::..|.:..:|::||||||:|
Yeast   155 LAPTRELAQQIKETFDSLGSLM-------GVRSTCIVGGMNMMDQARDLMRKPHIIIATPGRLMD 212

  Fly   323 HLQNSPDFLYKNLQCLIIDEVDRILEIGFEEELKQIINLLP-KRRQTMLFSATQTARIEALSKLA 386
            ||:|:..|..:.|:.|::||.||:|::.|...|.:|:.::| :.|.|.|||||.|::|:.|.:.:
Yeast   213 HLENTKGFSLRKLKFLVMDEADRLLDMEFGPVLDRILKIIPTQERTTYLFSATMTSKIDKLQRAS 277

  Fly   387 LKSEPIYVGVHDNQDTATVDGLEQGYIVCPSEKRLLVLFTFLKKNRKKKVMVFFSSCMSVKYHHE 451
            | :.|:...|.:...  |||.|.|..:|.|...:...|...|.:...|.:::|..:..:.:....
Yeast   278 L-TNPVKCAVSNKYQ--TVDTLVQTLMVVPGGLKNTYLIYLLNEFIGKTMIIFTRTKANAERLSG 339

  Fly   452 LFNYIDLPVTSIHGKQKQTKRTTTFFQFCNAESGILLCTDVAARGLDIPQVDWIVQYDPPDDPRE 516
            |.|.::...|::||...|.:|..:...|...:..||:.|||||||||||.||.:|.||.|.|.:.
Yeast   340 LCNLLEFSATALHGDLNQNQRMGSLDLFKAGKRSILVATDVAARGLDIPSVDIVVNYDIPVDSKS 404

  Fly   517 YIHRVGRTARGSGTSGHALLLMRPEELGFLRYLKAAKVPLNEFEFSWQKIADIQLQLEKLIAKNY 581
            |||||||||| :|.||.::.|:...:|                        ::.|::|:::.|..
Yeast   405 YIHRVGRTAR-AGRSGKSISLVSQYDL------------------------ELILRIEEVLGKKL 444

  Fly   582 FLNQSAKEAFKSYVRAYDSHQLKQIFNVNTLDLQAVAKSFG 622
            ......|....:...:.|....:.:..:|..:.:.:|:..|
Yeast   445 PKESVDKNIILTLRDSVDKANGEVVMEMNRRNKEKIARGKG 485

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_524446.3	DEADc_DDX18	198..395	CDD:350700	79/209 (38%)
		SF2_C_DEAD	408..537	CDD:350174	49/128 (38%)
		DUF4217	570..627	CDD:464056	8/53 (15%)
RRP3	NP_011932.2	SrmB	82..489	CDD:440279	145/447 (32%)