Protein Alignment pit and MSS116

DIOPT Version :10

• Sequence 1: NP_524446.3
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_010480.1
• Gene: MSS116 / 851775
• SGDID: S000002602
• Length: 664
• Species: Saccharomyces cerevisiae
• Alignment Length: 539
• Identity: 156/539 - (28%)
• Similarity: 278/539 - (51%)
• Gaps: 70/539 - (12%)

  Fly   133 QEDEDEEEPVPAKKTKLLPNKSKAQNGKPAKDDEPFTVESSLAALDYRDSDDRSFASLKGAVSEA 197
            :||:||........:||: :..|..|.|..      |::|.|.               :|.:.:.
Yeast    74 REDDDEVHFDKTTFSKLI-HVPKEDNSKEV------TLDSLLE---------------EGVLDKE 116

  Fly   198 TLRAIKEMGFTEMTEIQSKSLTPLL--KGRDLVGAAQTGSGKTLAFLIPAVELINKLRFMPRNGT 260
            ..:||..|.|..:|.:|.|::.|:|  :..|::..|:||:|||.|||||..:.:...:|..:...
Yeast   117 IHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMV 181

  Fly   261 GVIIISPTRELSMQTFGVLKELMAHHHHTYGL-------VMGGSNRQVESEKLGK-GINILVATP 317
            ..:|::|||:|::|....:|::   |...|||       ::||::.:....|:.| ..||::|||
Yeast   182 KAVIVAPTRDLALQIEAEVKKI---HDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIATP 243

  Fly   318 GRLLDHLQNSPDFLYKNLQCLIIDEVDRILEIGFEEELKQIINLLPKRR-------QTMLFSATQ 375
            |||:|.|:...:..::.:...::||.||:|||||.::|:.|..:|.::.       :|:|||||.
Yeast   244 GRLIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLLFSATL 308

  Fly   376 TARIEAL-SKLALKSEPIYVGVHDNQDTATVDGLEQGYIVCPSEKRLLVLFT---FLKKNRKK-- 434
            ..:::.| :.:..|.|.:::...|..:....:.::|..::  |||....:|.   .:||..|:
Yeast   309 DDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVI--SEKFANSIFAAVEHIKKQIKERD 371

  Fly   435 ---KVMVFFSSCMSVKYHHELFNYI------DLPVTSIHGKQKQTKRTTTFFQFCNAESGILLCT 490
               |.::|   ..:||:...|.:.:      |||:...|||..|.|||:...:|...|||||:||
Yeast   372 SNYKAIIF---APTVKFTSFLCSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCT 433

  Fly   491 DVAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGFLRYLKAAKVP 555
            ||.|||:|.|.|..::|...|.:...||||:||||| ||..|.::|.:..:||.|:|.|:.||..
Yeast   434 DVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTAR-SGKEGSSVLFICKDELPFVRELEDAKNI 497

  Fly   556 LNEFEFSWQKIADIQLQLEKLIAKNYFLNQSAKEAFKSYVRAYDSHQLKQIFNVNTLDLQAVAKS 620
            :...:..::...:|:.::.:.:.:.   .:...:...|.:.:|.|...:..|:...: |..:|.:
Yeast   498 VIAKQEKYEPSEEIKSEVLEAVTEE---PEDISDIVISLISSYRSCIKEYRFSERRI-LPEIAST 558

  Fly   621 FGFLV-PPVVDLKVGAAKR 638
            :|.|: .|  .||:..::|
Yeast   559 YGVLLNDP--QLKIPVSRR 575

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_524446.3	DEADc_DDX18	198..395	CDD:350700	68/214 (32%)
		SF2_C_DEAD	408..537	CDD:350174	53/142 (37%)
		DUF4217	570..627	CDD:464056	8/57 (14%)
MSS116	NP_010480.1	SrmB	113..525	CDD:440279	131/423 (31%)