DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment pit and EMB1586

DIOPT Version :9

Sequence 1:	NP_001287459.1	Gene:	pit / 42595	FlyBaseID:	FBgn0266581	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_001322468.1	Gene:	EMB1586 / 837833	AraportID:	AT1G12770	Length:	551	Species:	Arabidopsis thaliana

Alignment Length:	468	Identity:	118/468 - (25%)
Similarity:	204/468 - (43%)	Gaps:	90/468 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   160 KPAKDDEPFTVESSLAALDYRDSDDRSFASLKGAVSEATLRAIKEMGFTEMTEIQSKSLTPLLKG 224
            |..|:.:|..:.|.|.:.       :||..|  .:.::.|.:::..||:..|::||.::..::||
plant    92 KVVKEKKPAEIVSPLFSA-------KSFEEL--GLPDSLLDSLEREGFSVPTDVQSAAVPAIIKG 147

  Fly   225 RDLVGAAQTGSGKTLAFLIPAVELINKLRFMPRNGTG---------VIIISPTRELSMQTFGVLK 280
            .|.|..:.||||||||:|:|.:..|..|....|:...         .:|::|:|||.||....::
plant   148 HDAVIQSYTGSGKTLAYLLPILSEIGPLAEKSRSSHSENDKRTEIQAMIVAPSRELGMQIVREVE 212

  Fly   281 ELMAH-HHHTYGLVMGGSNRQVESEKLGKG-INILVATPGRLLDHLQNSPDFLYKNLQCLIIDEV 343
            :|:.. |......::||:||..:.|.|.|. ..|:|.||||:.: :...........:.|::|||
plant   213 KLLGPVHRRMVQQLVGGANRMRQEEALKKNKPAIVVGTPGRIAE-ISKGGKLHTHGCRFLVLDEV 276

  Fly   344 DRILEIGFEEELKQIINLLPKR--------------RQTMLFSATQTARIEALSKLALKSEPIYV 394
            |.:|...|.|::.:|:..:.||              |||:|.|||....:...:| :...||:.|
plant   277 DELLSFNFREDIHRILEHVGKRSGAGPKGEVDERANRQTILVSATVPFSVIRAAK-SWSHEPVLV 340

  Fly   395 GVH------------------------DNQDTATVDGLEQG--YIVCPSEKRLLV---------- 423
            ..:                        |.|...|:..|...  :..|.|:.:..|
plant   341 QANKVTPLDTVQPSAPVMSLTPTTSEADGQIQTTIQSLPPALKHYYCISKHQHKVDTLRRCVHAL 405

  Fly   424 ----LFTFLKKNRKKKVMVFFSSCMSVKYHHELFNYIDLPVTSIHGKQKQTKRTTTFFQFCNAES 484
                :..|:..:|:.|.:|:       |......|..::     ||...:..|:|...:|.|.|.
plant   406 DAQSVIAFMNHSRQLKDVVY-------KLEARGMNSAEM-----HGDLGKLGRSTVLKKFKNGEI 458

  Fly   485 GILLCTDVAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGFLRYL 549
            .:|:..:::|||||:.:.|.:|..:.|.|...|.||.|||.| .|..|..:.:....::..::.:
plant   459 KVLVTNELSARGLDVAECDLVVNLELPTDAVHYAHRAGRTGR-LGRKGTVVTVCEESQVFIVKKM 522

  Fly   550 -KAAKVPLNEFEF 561
             |...:|....||
plant   523 EKQLGLPFLYCEF 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_001287459.1	SrmB	186..677	CDD:223587	113/442 (26%)
		DEADc	187..394	CDD:238167	68/231 (29%)
		HELICc	408..537	CDD:238034	36/144 (25%)
		DUF4217	569..627	CDD:290667
EMB1586	NP_001322468.1	P-loop_NTPase	112..340	CDD:304359	68/231 (29%)
		DEXDc	125..349	CDD:214692	66/225 (29%)
		HELICc	384..510	CDD:238034	35/138 (25%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010