DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment pit and AT5G05450

DIOPT Version :9

Sequence 1:	NP_001287459.1	Gene:	pit / 42595	FlyBaseID:	FBgn0266581	Length:	680	Species:	Drosophila melanogaster
Sequence 2:	NP_196164.1	Gene:	AT5G05450 / 830428	AraportID:	AT5G05450	Length:	593	Species:	Arabidopsis thaliana

Alignment Length:	522	Identity:	180/522 - (34%)
Similarity:	283/522 - (54%)	Gaps:	45/522 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly   187 FASLKGAVSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVELINK 251
            |:.|:..:|...:.|:.:..|...|.:|:.::..|...:|:...|.|||||||||::|.||::.:
plant    16 FSDLEPPLSGDIIEALNQSDFEFCTPVQAATIPLLCSYKDVAVDAATGSGKTLAFVVPLVEILRR 80

  Fly   252 LRFMPRNGTGV--IIISPTRELSMQTFGVLKELMAHHHHTYG-LVMGGSNRQVESE-KL--GKGI 310
            ....|.....|  :|||||||||.|.:.|.:..::...:... |::||  |:|::: |:  .:|.
plant    81 STSFPPKPHQVMGVIISPTRELSTQIYNVAQPFVSTLANVNSVLLVGG--REVKADMKIIEEEGC 143

  Fly   311 NILVATPGRLLDHLQNSPDFLYKNLQCLIIDEVDRILEIGFEEELKQIINLLPKRRQTMLFSATQ 375
            |:|:.|||||.|.::......::||:.||:||.||:||:||:.::..||:.|||:|:|.||||||
plant   144 NVLIGTPGRLSDIMERMEILDFRNLEILILDEADRLLEMGFQRQVNYIISRLPKQRRTGLFSATQ 208

  Fly   376 TARIEALSKLALKSEPIYVGVHDNQ---------DTATVDGLEQGYIVCPSEKRLLVLFTFLKKN 431
            |..:|.|:|..|:: |:.|.|....         ::.|..||...|:.|.::|:...|...|.||
plant   209 TEGVEELAKAGLRN-PVRVEVRAKSKSESSQQLTNSKTPSGLHLEYMECEADKKSSQLVDLLIKN 272

  Fly   432 RKKKVMVFFSSCMSVKYHHELFNYI----DLPVTSIHGKQKQTKRTTTFFQFCNAESGILLCTDV 492
            ..||::|||.:|.||.|...:.:.|    .:.:..|||..||..|......|..|.||.||||||
plant   273 SDKKLIVFFMTCASVDYWGLVLSKIPALKSISLIPIHGDMKQNARDKALASFTKASSGALLCTDV 337

  Fly   493 AARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGFLRYLKAAKVPLN 557
            ||||||||.:|::||||||.||..:.||.||||| .|..|.|::.:.|:|..::.:::..:|||.
plant   338 AARGLDIPGIDYVVQYDPPQDPNMFNHRAGRTAR-LGRQGRAIVFLLPKEEAYVEFMRIRRVPLE 401

  Fly   558 EFEFSWQKIADIQLQLEKLIAKNYFLNQSAKEAFKSYVRAYDSHQLKQIFNVNTLDLQAVAKSFG 622
            |.:.| :..:|:...:.....|:..:.:...:||.|:||||..|....||....|::..:|..:|
plant   402 ERKCS-EDASDVIPIIRSAAMKDRAVMEKGLKAFVSFVRAYKEHHCSFIFRWKDLEIGKLAMGYG 465

  Fly   623 FL-VPPVVDLKVGAAKRERPEKRVGGGGF-----------GFYKKMNEGSASKQRHFKQVNRDQA 675
            .| :|.:.::|         :.|:...||           .|..|..|....:....::..|.:.
plant   466 LLYLPSMSEVK---------QHRLSSEGFTPVEGVKFEEIKFKDKYREKQRQQNLQVRKEKRQEE 521

  Fly   676 KK 677
            ||
plant   522 KK 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_001287459.1	SrmB	186..677	CDD:223587	178/520 (34%)
		DEADc	187..394	CDD:238167	81/212 (38%)
		HELICc	408..537	CDD:238034	61/132 (46%)
		DUF4217	569..627	CDD:290667	15/58 (26%)
AT5G05450	NP_196164.1	SrmB	12..501	CDD:223587	175/498 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920