DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment pit and RH1

DIOPT Version :9

Sequence 1:NP_001287459.1 Gene:pit / 42595 FlyBaseID:FBgn0266581 Length:680 Species:Drosophila melanogaster
Sequence 2:NP_193320.6 Gene:RH1 / 827266 AraportID:AT4G15850 Length:522 Species:Arabidopsis thaliana


Alignment Length:418 Identity:107/418 - (25%)
Similarity:185/418 - (44%) Gaps:88/418 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly   200 RAIKEMGFTEMTEIQ----SKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVELINKLRFMPRNGT 260
            :|::.||.:.:..:|    .:::.|....||:...:.|||||||::.:|.|:|   |...|....
plant    44 KALENMGISSLFPVQVAVWHETIGPGGFERDICVNSPTGSGKTLSYALPIVQL---LASRPVRCL 105

  Fly   261 GVIIISPTRELSMQTFGVLKELMAHHHHTYGLVMGGS------NRQVESEKLGKGI--------- 310
            ..:::.|||:|::|...|...:......:.|..:|.|      ::.:::.||..||         
plant   106 RALVVLPTRDLALQVKDVFDAIAPAVGLSVGSAVGQSSIAGEISQLIKTPKLDAGICYDPDDLSQ 170

  Fly   311 ------NILVATPGRLLDHLQNSPDFLYKNLQCLIIDEVDRILEIGFEEELKQIINL-------- 361
                  :|||||||||:||:.|:..|..::|:.|::||.||:|...::..|..::.|        
plant   171 NLESAVDILVATPGRLMDHINNTKGFTLEHLRYLVVDETDRLLREAYQSWLPTVLQLTQTSDDSL 235

  Fly   362 -------LPK--------RRQT---------------MLFSATQTARIEALSKLALKSEPIYVGV 396
                   :|.        |||:               |:.|||.|.....|.:|.| ..|:::  
plant   236 FPSFTPFVPSAFGSLQTVRRQSVERGFKGKPYPRLVKMVLSATLTQDPSKLIQLDL-HHPLFM-- 297

  Fly   397 HDNQDTATVDG--------LEQGYIVCPSEKRLLVLFTFLKKNRKKKVMVFFSSCMSVKYHHELF 453
                   |..|        ||...::|.:..:.:.|...||....:|.::|.||..:.:...:|.
plant   298 -------TTGGSRYRLPEKLECLRLICETGMKPVYLVALLKSWEGEKCIIFTSSVETTRRLCKLL 355

  Fly   454 NYIDLP---VTSIHGKQKQTKRTTTFFQFCNAESGILLCTDVAARGLDIPQVDWIVQYDPPDDPR 515
            |:...|   .....|...|:.|:.....|...:..:|:.:|...||:|:..|..::.||.|...:
plant   356 NFFGDPKIKAKEYSGGLNQSLRSKELKAFRKGDIQVLVASDALTRGMDVKGVTNVINYDMPPFAK 420

  Fly   516 EYIHRVGRTARGSGTSGHALLLMRPEEL 543
            .:|||.||||| :|.:|....|:...|:
plant   421 TFIHRAGRTAR-AGQAGRCFTLLSNHEV 447

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
pitNP_001287459.1 SrmB 186..677 CDD:223587 107/418 (26%)
DEADc 187..394 CDD:238167 67/256 (26%)
HELICc 408..537 CDD:238034 36/131 (27%)
DUF4217 569..627 CDD:290667
RH1NP_193320.6 P-loop_NTPase 37..>213 CDD:304359 51/171 (30%)
DEXDc 46..303 CDD:214692 68/269 (25%)
HELICc 319..441 CDD:238034 33/122 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D973872at2759
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.920

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