Protein Alignment pit and Ddx55

DIOPT Version :9

• Sequence 1: NP_001287459.1
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_080685.2
• Gene: Ddx55 / 67848
• MGIID: 1915098
• Length: 600
• Species: Mus musculus
• Alignment Length: 542
• Identity: 182/542 - (33%)
• Similarity: 292/542 - (53%)
• Gaps: 60/542 - (11%)

  Fly   186 SFASLKGAVSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVE-LI 249
            ::.||:..:....|.|::|:||..||.:||.::...:|.:|:...|.|||||||||:||.:| |:
Mouse     8 AWESLQVPLHPRVLGALRELGFPHMTPVQSATIPLFMKNKDVAAEAVTGSGKTLAFVIPILEILL 72

  Fly   250 NKLRFMPRNGTGVIIISPTRELSMQTFGVLKELMAH---HHHTYGLVM--GGSNRQVESEKLGK- 308
            .:...:.:|..|.|:|:|||||::|    :.|:::|   |...:..::  ||.|...:.|:..:
Mouse    73 RREEKLKKNQVGAIVITPTRELAIQ----IDEVLSHFTKHFPQFSQILWIGGRNPGEDVERFKQH 133

  Fly   309 GINILVATPGRLLDHLQNSPDFL-----YKNLQCLIIDEVDRILEIGFEEELKQIINLLPKRRQT 368
            |.||:|||||||.|..:...:.|     .|:|..|::||.||:|::|||..:..|:..|||:|:|
Mouse   134 GGNIIVATPGRLEDMFRRKAEGLDLASCVKSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRT 198

  Fly   369 MLFSATQTARIEALSKLALKSEPIYV-----GVHDNQDTATVDGLEQGYIVCPSEKRLLVLFTFL 428
            .|||||||..:|.|.:..|:: |:.:     ||..:....|...||..|::|.::::...|..||
Mouse   199 GLFSATQTQEVENLVRAGLRN-PVRISVKEKGVAASSTQKTPSRLENHYMICKADEKFNQLVHFL 262

  Fly   429 KKNRKKKVMVFFSSCMSVKYHHELFNYI--DLPVTSIHGKQKQTKRTTTFFQFCNAESGILLCTD 491
            :..:::|.:||||:|..|:|:.:....:  .:.:..||||.|. ||...|.:|...:||||:|||
Mouse   263 RSRQQEKHLVFFSTCACVEYYGKALEALLKKVKILCIHGKMKY-KRNKIFMEFRKLQSGILVCTD 326

  Fly   492 VAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGFLRYLKA-AKVP 555
            |.|||:|||:|:|::|||||.:...::||.||||| .|..|.||:.:.|.|..::.:|.. .|.|
Mouse   327 VMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTAR-IGHGGSALVFLLPMEEAYINFLAINQKCP 390

  Fly   556 LNEFEFSWQKIADIQLQLEKLIAKNYFLNQSAKEAFKSYVRAYDSHQLKQIFNVNTLDLQAVAKS 620
            |.|.......| |:..:|..:...:..:.:...:||.|:|:||..|:...||.:..||...:|:.
Mouse   391 LQEMSLQRNTI-DLLPKLRAMALADRAVFEKGMKAFVSFVQAYAKHECSLIFRLKDLDFAGLARG 454

  Fly   621 FGFL----------------VPPVVDL---------------KVGAAKRERPEKRVGGGGFGFYK 654
            |..|                ||..:|.               |:...||:...:..|...|...|
Mouse   455 FALLRMPRMPELRGKQFPDFVPVDIDTDTIPFKDKIREKQRQKLLEQKRKERSENEGRKKFIKNK 519

  Fly   655 KMNEGSASKQRHFKQVNRDQAK 676
            ..::..|.|:|. |::|..:.|
Mouse   520 AWSKQKAKKERK-KKMNAKRKK 540

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_001287459.1	SrmB	186..677	CDD:223587	182/542 (34%)
		DEADc	187..394	CDD:238167	84/218 (39%)
		HELICc	408..537	CDD:238034	56/130 (43%)
		DUF4217	569..627	CDD:290667	16/73 (22%)
Ddx55	NP_080685.2	DEADc	9..224	CDD:238167	84/219 (38%)
		Q motif	9..37		9/27 (33%)
		DEXDc	24..228	CDD:214692	80/208 (38%)
		DEAD box	171..174		2/2 (100%)
		Helicase_C	252..363	CDD:278689	48/112 (43%)
		DUF4217	403..462	CDD:290667	15/58 (26%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	499..551		11/43 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	2.920