Protein Alignment pit and DDX55

DIOPT Version :9

• Sequence 1: NP_001287459.1
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: XP_016875199.1
• Gene: DDX55 / 57696
• HGNCID: 20085
• Length: 618
• Species: Homo sapiens
• Alignment Length: 548
• Identity: 184/548 - (33%)
• Similarity: 292/548 - (53%)
• Gaps: 73/548 - (13%)

  Fly   186 SFASLKGAVSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVE-LI 249
            |:.||...:....|.|::|:||..||.:||.::...::.:|:...|.|||||||||:||.:| |:
Human     8 SWESLPVPLHPQVLGALRELGFPYMTPVQSATIPLFMRNKDVAAEAVTGSGKTLAFVIPILEILL 72

  Fly   250 NKLRFMPRNGTGVIIISPTRELSMQTFGVLKELMAH---HHHTYGLVM--GGSNRQVESEKL-GK 308
            .:...:.::..|.|||:|||||::|    :.|:::|   |...:..::  ||.|...:.|:. .:
Human    73 RREEKLKKSQVGAIIITPTRELAIQ----IDEVLSHFTKHFPEFSQILWIGGRNPGEDVERFKQQ 133

  Fly   309 GINILVATPGRLLDHLQNSPDFL-----YKNLQCLIIDEVDRILEIGFEEELKQIINLLPKRRQT 368
            |.||:|||||||.|..:...:.|     .::|..|::||.||:|::|||..:..|:..|||:|:|
Human   134 GGNIIVATPGRLEDMFRRKAEGLDLASCVRSLDVLVLDEADRLLDMGFEASINTILEFLPKQRRT 198

  Fly   369 MLFSATQTARIEALSKLALKSEPIYVGVHDNQDTA-----TVDGLEQGYIVCPSEKRLLVLFTFL 428
            .|||||||..:|.|.:..|:: |:.|.|.:....|     |...||..|:||.::::...|..||
Human   199 GLFSATQTQEVENLVRAGLRN-PVRVSVKEKGVAASSAQKTPSRLENYYMVCKADEKFNQLVHFL 262

  Fly   429 KKNRKKKVMVFF------------------SSCMSVKYHHELFNYI--DLPVTSIHGKQKQTKRT 473
            :.::::|.:|||                  |:|..|:|:.:....:  .:.:..||||.|. ||.
Human   263 RNHKQEKHLVFFRYSSGLCGRGIRDSARMCSTCACVEYYGKALEVLVKGVKIMCIHGKMKY-KRN 326

  Fly   474 TTFFQFCNAESGILLCTDVAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLM 538
            ..|.:|...:||||:||||.|||:|||:|:|::|||||.:...::||.||||| .|..|.||:.:
Human   327 KIFMEFRKLQSGILVCTDVMARGIDIPEVNWVLQYDPPSNASAFVHRCGRTAR-IGHGGSALVFL 390

  Fly   539 RPEELGFLRYLKA-AKVPLNEFEFSWQKIADIQLQLEKLIAKNYFLNQSAKEAFKSYVRAYDSHQ 602
            .|.|..::.:|.. .|.||.|.: ..:..||:..:|:.:...:..:.:...:||.|||:||..|:
Human   391 LPMEESYINFLAINQKCPLQEMK-PQRNTADLLPKLKSMALADRAVFEKGMKAFVSYVQAYAKHE 454

  Fly   603 LKQIFNVNTLDLQAVAKSFGFLVPPVVDLKVGAAKRERPEKR-----------VGGGGFGFYKKM 656
            ...||.:..||..::|:.|..|..|           :.||.|           |......|..|:
Human   455 CNLIFRLKDLDFASLARGFALLRMP-----------KMPELRGKQFPDFVPVDVNTDTIPFKDKI 508

  Fly   657 NEGSASK----QRHFKQVNRDQAKKFMR 680
            .|....|    ||..|..|..: :||::
Human   509 REKQRQKLLEQQRREKTENEGR-RKFIK 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_001287459.1	SrmB	186..677	CDD:223587	182/543 (34%)
		DEADc	187..394	CDD:238167	82/218 (38%)
		HELICc	408..537	CDD:238034	57/148 (39%)
		DUF4217	569..627	CDD:290667	16/57 (28%)
DDX55	XP_016875199.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920