Protein Alignment pit and Ddx56

DIOPT Version :9

• Sequence 1: NP_001287459.1
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_080814.1
• Gene: Ddx56 / 52513
• MGIID: 1277172
• Length: 546
• Species: Mus musculus
• Alignment Length: 510
• Identity: 135/510 - (26%)
• Similarity: 227/510 - (44%)
• Gaps: 84/510 - (16%)

  Fly   199 LRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVE-LINKLRFMPRNGTGV 262
            |:|:.::|::..|.||.|::...|:|:||:..|:||||||.|:.||.:: |::|....|.....|
Mouse    19 LQAVTDLGWSRPTLIQEKAIPLALEGKDLLARARTGSGKTAAYAIPMLQSLLHKKATGPVMEQAV 83

  Fly   263 --IIISPTRELSMQTFGVLKELMAHHHHTYGLVM------GGSNRQVESEKLGKGINILVATPGR 319
              :::.||:||:.|...::::|.|:......:..      ..|.|.|..||    .:::|.||.|
Mouse    84 RGLVLVPTKELARQAQAMIQQLAAYCARDVRVANVSAAEDSASQRAVLMEK----PDVVVGTPSR 144

  Fly   320 LLDHLQNSPDFLYKNLQCLIIDEVDRILEIGFEEELKQIINLLPKRRQTMLFSATQTARIEALSK 384
            :|.|||.:...|..:|:.|::||.|.:...|||:|||.::..||:..|..|.|||....::.|.:
Mouse   145 VLSHLQQNTLKLRDSLELLVVDEADLLFSFGFEDELKSLLCHLPRIYQAFLMSATFNEDVQTLKE 209

  Fly   385 LALKSEPIYVGVHDNQDTATVDGLEQGYIVCPSEK-RLLVLFTFLKKNRKKKVMVFFSSCMSVKY 448
            |.|.: |:.:.:.::| ....|.|:|..:||.:|: :.|:|:..||.:..:...:.|.:.:...|
Mouse   210 LVLHN-PVTLKLQESQ-LPGPDQLQQFQVVCETEEDKFLLLYALLKLSLIRGKALLFVNTLERGY 272

  Fly   449 HHELF-NYIDLPVTSIHGKQKQTKRTTTFFQFCNAESGILLCTDV-------------------- 492
            ...|| ....:|...::|:.....|.....||.......::.||.
Mouse   273 RLRLFLEQFSIPSCVLNGELPLRSRCHIISQFNQGLYDCVIATDAEILGPQVKGKRRGRGSKGNK 337

  Fly   493 -------AARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGFLRYLK 550
                   .|||:|...|..::.:|.|.....|:||.||||| :...|..|..:.|.|..||..::
Mouse   338 ASDPESGVARGIDFHHVSAVLNFDLPPTAEAYVHRAGRTAR-ANNPGIVLTFVLPAEQPFLGKIE 401

  Fly   551 -----AAKVPLNEFEFSWQKIADIQLQLEKLIAKNYFLNQSAKEAFKSYVR----------AYDS 600
                 ..:.|:         :...|.|:|::.:..|....:.:...|..:|          ...|
Mouse   402 DLLSGEGEAPI---------LLPYQFQMEEIESFRYRCRDAMRSVTKQAIREARLKEIKEELLHS 457

  Fly   601 HQLKQIFNVNTLDLQ----------AVAKSF-----GFLVPPVVDLKVGAAKRER 640
            .:||..|..|..|||          ||.|..     .:|||..:...|...|:.|
Mouse   458 EKLKTYFEDNPRDLQLLRHDLPLHPAVVKPHLGHVPDYLVPAALRGLVHPRKKRR 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_001287459.1	SrmB	186..677	CDD:223587	135/510 (26%)
		DEADc	187..394	CDD:238167	68/203 (33%)
		HELICc	408..537	CDD:238034	37/157 (24%)
		DUF4217	569..627	CDD:290667	19/82 (23%)
Ddx56	NP_080814.1	Q motif	7..35		5/15 (33%)
		SrmB	9..544	CDD:223587	135/510 (26%)
		P-loop_NTPase	9..219	CDD:304359	68/204 (33%)
		DEAD box	166..169		2/2 (100%)
		HELICc	234..388	CDD:238034	35/154 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	324..344		0/19 (0%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	508..546		2/5 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010