Protein Alignment pit and CG7878

DIOPT Version :10

• Sequence 1: NP_524446.3
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_649767.1
• Gene: CG7878 / 40959
• FlyBaseID: FBgn0037549
• Length: 703
• Species: Drosophila melanogaster
• Alignment Length: 662
• Identity: 165/662 - (24%)
• Similarity: 271/662 - (40%)
• Gaps: 163/662 - (24%)

  Fly    26 KGNK---NAQKQEPPKQNGNKPSKKP-EKLSKKHVAKDEDDDLEEDFQEAPLPKKKQQKQPPKKQ 86
            |||.   |....|..|.||:...... |.|:|..:|.     ....:.:.|...|...|:.|
  Fly   184 KGNSYEFNPTSSESNKDNGDLTGIIDWEALNKASIAA-----TAARWSKCPPLTKNFYKEAP--- 240

  Fly    87 QIQVANSDSESDDDEQEDEADEDSDLDEVAEVDEEDVDSGSEDDDQQEDEDEEEPVPAKKTKLLP 151
                                       |||.:.:.:::...|::::.......||...:.:..:|
  Fly   241 ---------------------------EVANLTKSEIERIREENNKITVSYVFEPKEGETSPPIP 278

  Fly   152 NKSKAQNGKPAKDDEPFTVESSLAALDYRDSDDRSFASLKGAVSEATLRAIKEMGFTEMTEIQSK 216
            |        |.     :|.|...|  :|.|                .|..|.:|||::.:.|||:
  Fly   279 N--------PV-----WTFEQCFA--EYPD----------------MLEEITKMGFSKPSPIQSQ 312

  Fly   217 SLTPLLKGRDLVGAAQTGSGKTLAFLIPAVELINKLRFMP---RNGTGVIIISPTRELSMQTFGV 278
            :...||:|.|::|.||||:|||||||:|.: :..:.:..|   |.|..|::::|||||::|.
  Fly   313 AWPILLQGHDMIGIAQTGTGKTLAFLLPGM-IHTEYQSTPRGTRGGANVLVLAPTRELALQI--- 373

  Fly   279 LKELMAHHHHTYGL----VMGGSNRQVESEKLGKGINILVATPGRLLDHLQ-NSPDFLYKNLQCL 338
              |:....:...|:    |.||.||.::...|.:|..|::.|||||.|.:. |..|  ...:..|
  Fly   374 --EMEVKKYSFRGMKAVCVYGGGNRNMQISDLERGAEIIICTPGRLNDLIMANVID--VSTITYL 434

  Fly   339 IIDEVDRILEIGFEEELKQIINLLPKRRQTMLFSATQTARIEALSKLALKSEPIYVGVHDNQDTA 403
            ::||.||:|::|||.::::::..:...|||::.|||....:..|::..:|: ||.|.| .:.|.|
  Fly   435 VLDEADRMLDMGFEPQIRKVMLDIRPDRQTIMTSATWPPGVRRLAQSYMKN-PIQVCV-GSLDLA 497

  Fly   404 TVDGLEQGYIVCPSEKRLLVLFTFLKKNRKK--KVMVFFSSCMSVKYHHELFNYIDLP---VTSI 463
            ....::|...:...:.......|...||...  |:::|   |.......:|.:.:.|.   ...|
  Fly   498 ATHSVKQIIKLMEDDMDKFNTITSFVKNMSSTDKIIIF---CGRKVRADDLSSELTLDGFMTQCI 559

  Fly   464 HGKQKQTKRTTTFFQFCNAESGILLCTDVAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGS 528
            ||.:.|..|........:....||:.||||:|||||..:..::.||.|.:..||:||||||.| :
  Fly   560 HGNRDQMDREQAIADIKSGVVRILVATDVASRGLDIEDITHVINYDFPHNIEEYVHRVGRTGR-A 623

  Fly   529 GTSGHALLLMRPEELGFLRYLKAAKVPLNEFEFSWQKIADIQLQLEKLIAKNYFLNQSAKEAFKS 593
            |..|.::.....|:....:.|...   |.|.|   |::.|
  Fly   624 GRQGTSISFFTREDWAMAKELIEI---LQEAE---QEVPD------------------------- 657

  Fly   594 YVRAYDSHQLKQIFNVNTLDLQAVAKSFGFLVPPVVDLKVGAAKRERPEKRVGGGGFGFY-KKMN 657
                               :|..:|:.|               |..:.::...|||||.. .:..
  Fly   658 -------------------ELHNMARRF---------------KAMKDKRAAEGGGFGGRGGRFG 688

  Fly   658 EGSASKQRHFKQ 669
            .|....:|:|.|
  Fly   689 GGRGGGRRNFDQ 700

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_524446.3	DEADc_DDX18	198..395	CDD:350700	72/204 (35%)
		SF2_C_DEAD	408..537	CDD:350174	39/133 (29%)
		DUF4217	570..627	CDD:464056	3/56 (5%)
CG7878	NP_649767.1	KH_1	92..152	CDD:459630
		DEAD-like_helicase_N	174..663	CDD:475120	153/608 (25%)