Protein Alignment pit and CG6418

DIOPT Version :9

• Sequence 1: NP_001287459.1
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_648413.1
• Gene: CG6418 / 39218
• FlyBaseID: FBgn0036104
• Length: 791
• Species: Drosophila melanogaster
• Alignment Length: 700
• Identity: 195/700 - (27%)
• Similarity: 309/700 - (44%)
• Gaps: 168/700 - (24%)

  Fly    53 KKHVAKD---EDDD--LEEDFQEAPLPKKKQQKQPP---KKQQIQVANSDSESDDD--------- 100
            :||...|   :|||  .|::.::|.:|.......||   |||:      ||:||:|
  Fly    84 RKHHTDDDYFDDDDEPREKEIEQAYIPAPGSPGAPPTSAKKQE------DSDSDEDPLEQFMAGI 142

  Fly   101 ------EQEDEADED------SDLDEVAEVDEEDV-------------DSGSEDDDQQEDEDEEE 140
                  |:..:|.:.      .|:|:  |.|||..             |.|| |.:.:.|||...
  Fly   143 NQQVEKEKRQQAPKPPTQAVRGDIDD--EDDEESYYRYMKENPNAGLRDEGS-DQEIEYDEDGNP 204

  Fly   141 PVPAKKTKL--LPNKSKAQNGKPAKDDEPF-----TVESSLAALDYRDSDDRSFASLKG------ 192
            ..|.||..:  ||....::     .:.|||     |....:||||  |...|......|
  Fly   205 IAPPKKKDIDPLPPIYHSE-----IEYEPFEKNFYTQHDDIAALD--DEQVRELRRTLGVKVTGP 262

  Fly   193 ------------AVSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIP- 244
                        ...|..::|:::..:|:.|.||::::...|.|||::|.|:||||||.||:.|
  Fly   263 SPPKPVTSFGHFGFDEQLIKAVRKAEYTQPTPIQAQAVPTALSGRDIIGIAKTGSGKTAAFIWPM 327

  Fly   245 AVELINKLRFMPRNGTGVIIISPTRELSMQTFGVLKELMAHHHHTYGLVMGGSNRQVESEKLGKG 309
            .:.::::.:..|.:|...:|::||||||:|.:...|:....::.......||.::..:|:.|.:|
  Fly   328 LMHVMDQKQLKPGDGPIGLILAPTRELSLQIYNEAKKFGKVYNLNVVCCYGGGSKWEQSKALEQG 392

  Fly   310 INILVATPGRLLDHLQNSPDFLYKNLQCLIIDEVDRILEIGFEEELKQIINLLPKRRQTMLFSAT 374
            ..|:||||||::|.::.....| :.:..|::||.||:..:|||.:::.|.|.:...||.::||||
  Fly   393 AEIIVATPGRMIDMVKMKATNL-RRVTFLVLDEADRMFHMGFEPQVRSICNHVRPDRQCLMFSAT 456

  Fly   375 QTARIEALSKLALKSEPIYVGVHD----NQDTATVDGLEQGYIVCPSEKR-----LLVLFTFLKK 430
            ...|||.|::..| |:|:.:...|    |||      :.|...|.|:..:     |..|..||.:
  Fly   457 FKKRIERLARDVL-SDPVRIVQGDLNEANQD------ITQSVYVFPNPLQKWNWLLCHLVKFLSE 514

  Fly   431 NRKKKVMVF---------FSSCMSVKYHHELFNYIDLPVTSIHGKQKQTKRTTTFFQFCNAESGI 486
            .   .|::|         .|:.:.:|.::.|.         :||...|..|.....||...|..|
  Fly   515 G---SVLIFVTKKVDAETVSNNLLIKEYNCLL---------LHGDMDQADRNKVITQFKRKECDI 567

  Fly   487 LLCTDVAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGFLRYLKA 551
            |:.|||||||||||.:..:|.||...|...:.||:|||.| :|..|:|..|:..::..|..:|
  Fly   568 LVATDVAARGLDIPHIRNVVNYDTARDIETHTHRIGRTGR-AGEKGNAYTLVTDKDKEFAGHL-- 629

  Fly   552 AKVPLNEFEFSWQKIADIQLQLEKLIAKNYFLNQSAKEAFKSYVRAYDSHQLKQIFNVNTLDLQA 616
                :...|.:.|.:.|   .|.:|..|:.:...|..:..|.          |:..|.:|
  Fly   630 ----VRNLEGADQLVPD---DLMELAMKSSWFRSSRFKQGKG----------KRPTNTHT----- 672

  Fly   617 VAKSFGFLVPPVVDLKVGAAKRERPEKRVGGGGFGFYKKMNEGSASKQRH 666
                             |...|   ||..||||:| ....:|.:||...|
  Fly   673 -----------------GLGYR---EKGNGGGGYG-SAGGSESTASVSAH 701

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_001287459.1	SrmB	186..677	CDD:223587	145/517 (28%)
		DEADc	187..394	CDD:238167	70/225 (31%)
		HELICc	408..537	CDD:238034	45/142 (32%)
		DUF4217	569..627	CDD:290667	8/57 (14%)
CG6418	NP_648413.1	DEADc	271..475	CDD:238167	69/205 (34%)
		DEXDc	284..489	CDD:214692	71/212 (33%)
		Helicase_C	504..609	CDD:278689	39/117 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451735
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940