Protein Alignment pit and CG6227

DIOPT Version :9

• Sequence 1: NP_001287459.1
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_573020.2
• Gene: CG6227 / 32464
• FlyBaseID: FBgn0030631
• Length: 1224
• Species: Drosophila melanogaster
• Alignment Length: 722
• Identity: 185/722 - (25%)
• Similarity: 306/722 - (42%)
• Gaps: 168/722 - (23%)

  Fly    13 VKREKMKKELSQ------KKGNKNAQKQEPPKQNGNKPSKKPEKLSKKHVAKDEDDDLEEDFQEA 71
            |||....|...:      .|...:.:|:.||.....:..||||.::.|.      :.:||....|
  Fly   280 VKRPTFSKSFGKLGIGLATKAEADIKKEPPPVDTKKEIKKKPEPVAAKM------EIVEEPTVAA 338

  Fly    72 PLPKKKQQKQPPKKQQIQVANSDSESDDDEQEDEADE-DSDLDEV-------------------- 115
            ....||:.:||....:.:....|....:.|.|||.|. |:.:.||
  Fly   339 GEKTKKEPEQPHVGAKSEPEVEDKPQPEAEPEDEIDPLDAYMQEVNNEMRRVNNFVNPPAKSQGV 403

  Fly   116 ----------------AEVDEEDVDS--GSEDDDQQEDEDEEEPVPAKKTKLLPNKSKAQNGKPA 162
                            .||.|:::||  .|.:|:.::..|....:..|..|.|           |
  Fly   404 VILTGVAKKKTTTLKKGEVIEQNMDSLEYSSEDELEDIRDTAVNLAMKHRKEL-----------A 457

  Fly   163 KDD----------EPFTVE----SSLAALD---YRDSDDRSFASLKG-------------AVSEA 197
            |.|          :.|.||    :.:.|.|   ||  .|.....:||             .||:.
  Fly   458 KIDHSSVTYAPFRKNFYVEVPELTRMTAADVEKYR--SDLEGIQVKGKGCPKPIKTWAQCGVSKK 520

  Fly   198 TLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAV-ELINKLRFMPRNGTG 261
            .:..::.:||.:.|.||.:::..::.||||:|.|:|||||||||::|.. .::::......:|..
  Fly   521 EMEVLRRLGFEKPTPIQCQAIPAIMSGRDLIGIAKTGSGKTLAFILPMFRHILDQPSMEDGDGAI 585

  Fly   262 VIIISPTRELSMQTFGVLKELMAHHHHTYGL----VMGGSNRQVESEKLGKGINILVATPGRLLD 322
            .||::|||||.||....:::.    ..:.||    |.||:....:..:|.:|..|:|.||||::|
  Fly   586 AIIMAPTRELCMQIGKDIRKF----SKSLGLRPVCVYGGTGISEQIAELKRGAEIIVCTPGRMID 646

  Fly   323 HLQNSPDFL--YKNLQCLIIDEVDRILEIGFEEELKQIINLLPKRRQTMLFSATQTARIEALSKL 385
            .|..:...:  .:.:..:::||.||:.::|||.::.:||:.:...|||::||||...::|||::.
  Fly   647 MLAANSGRVTNLRRVTYVVLDEADRMFDMGFEPQVMRIIDNVRPDRQTVMFSATFPRQMEALARR 711

  Fly   386 ALKSEPIYVGVHDNQDTATVDGLEQGYIVCPSEKRLLVLFTFLK-----------KNRKKKVMVF 439
            .|| :||.|.|...  :.....:||..::...:.:...|...|.           .::::...:.
  Fly   712 ILK-KPIEVIVGGR--SVVCKEVEQHVVILNDDAKFFKLLELLGIYQEAGSIIVFVDKQENADIL 773

  Fly   440 FSSCMSVKYHHELFNYIDLPVTSIHGKQKQTKRTTTFFQFCNAESGILLCTDVAARGLDIPQVDW 504
            ....|...|          |..|:||...|..|.:|...|.:.:..:|:.|.|||||||:..:..
  Fly   774 LRDLMKASY----------PCMSLHGGIDQFDRDSTIIDFKSGKVRLLIATSVAARGLDVKDLIL 828

  Fly   505 IVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGFLRY---------LKAAKVPLNEFE 560
            :|.||.|:...:|:||.|||.| :|..|.|...:.||:   .||         |....:|. |.:
  Fly   829 VVNYDVPNHYEDYVHRCGRTGR-AGKKGSAYTFITPEQ---SRYAGDIIRAMDLSGTLIPA-ELQ 888

  Fly   561 FSWQKIADIQLQLEKLI-------AKNYFLNQ----SAKEAFKSYVRAY---DS----------- 600
            ..|.:...:|....|.:       .|.:..::    :|||:.|....|.   ||
  Fly   889 ALWTEYKALQEAEGKTVHTGGGFSGKGFKFDEQEFNAAKESKKLQKAALGLADSDDEEDIEQDID 953

  Fly   601 HQLKQIF 607
            .|::|||
  Fly   954 QQIEQIF 960

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_001287459.1	SrmB	186..677	CDD:223587	134/487 (28%)
		DEADc	187..394	CDD:238167	73/226 (32%)
		HELICc	408..537	CDD:238034	37/139 (27%)
		DUF4217	569..627	CDD:290667	14/64 (22%)
CG6227	NP_573020.2	SrmB	482..967	CDD:223587	139/503 (28%)
		DEADc	516..719	CDD:238167	71/207 (34%)
		HELICc	733..860	CDD:238034	36/137 (26%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45451476
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24031
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940