Protein Alignment pit and spb4

DIOPT Version :10

• Sequence 1: NP_524446.3
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_595956.1
• Gene: spb4 / 2540598
• PomBaseID: SPBC24C6.02
• Length: 606
• Species: Schizosaccharomyces pombe
• Alignment Length: 564
• Identity: 172/564 - (30%)
• Similarity: 284/564 - (50%)
• Gaps: 90/564 - (15%)

  Fly   186 SFASLKGAVSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVELIN 250
            ||.|:.  :.:....|:...||.:||.:|:.::...||.:|||..|.||||||||:|:|..:.:.
pombe     2 SFQSIN--IDKWLKNAVAAQGFKKMTPVQANAIPLFLKNKDLVVEAVTGSGKTLAYLLPCFDKVT 64

  Fly   251 KLRFMPRNGTGVIIISPTRELSMQTFGVLKELMAHHHHTYGLVMGGSNRQVESEKLG-------- 307
            : |.....|.|.:|::|||||:.|.|.|.|||:|:...:    :.|..:.|....:|
pombe    65 R-RDTDETGLGALIVAPTRELATQIFNVTKELLAYQPDS----LDGGKKLVADMYIGGKGTLTND 124

  Fly   308 ------KGINILVATPGRL---LDHLQNSPDFLYKNLQCLIIDEVDRILEIGFEEELKQIINLLP 363
                  |..::::.|||||   |.|:.:      |:|:.||:||.|.::::||:..|:.||:.||
pombe   125 LASFREKNPSVVIGTPGRLNEMLSHISS------KHLEILILDEADTLIDMGFQRTLQSIISQLP 183

  Fly   364 KRRQTMLFSATQTARIEALSKLALKSEPIYVGV---HDNQDTATVDGLEQGYIVCPSEKRLLVLF 425
            |:|:|.|||||....:.:..|:|.....:.|.|   ....||.|...|....:|.|...::..:.
pombe   184 KQRRTGLFSATMNDTVSSFLKIAGLRNSVRVSVTVTSKKIDTRTPSSLAIQSLVIPPIYKVQCMI 248

  Fly   426 TFLKKNRKKKVMVFFSSCMSVKYHHELFNYIDLP--VTSIHGKQKQTKRTTTFFQFCNA-ESGIL 487
            ..|.....:|.:||||||.||:|.:.||....||  :.::||:|.|:.|:..|.:|..: :..:|
pombe   249 HLLCTIEYEKAIVFFSSCASVEYFNSLFLTYKLPFEIVALHGQQVQSNRSRNFEKFKKSNKKTVL 313

  Fly   488 LCTDVAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLM---RPEELGFLRYL 549
            ..||:|:||||||.||:::|.|||.||:.:.||.||..| :|.:|.|::|:   |.||  :...|
pombe   314 FTTDIASRGLDIPNVDFVLQLDPPLDPKSFSHRCGRAGR-AGRAGVAIVLLNDGREEE--YEELL 375

  Fly   550 KAAKVPLNEFE-----FSWQKIADIQLQLEKLIAKNYFLNQSAKEAFKSYVRAYDSHQLKQIFNV 609
            :..|||:...:     ....::..:..:|.|:::|:..|......||.|:||||..|....||.:
pombe   376 RVRKVPITRIDTPIEALDLSRLKVLTHELRKIVSKDRDLYDKGLRAFVSHVRAYTKHHASFIFRI 440

  Fly   610 NTLDLQAVAKSFGFL----VPPVVDLKVG----------------------AAKRER-------P 641
            ..|||..:|.::..|    :|.:.|.::.                      .|:|.|       |
pombe   441 KDLDLGQLATAYALLHLPKMPELKDTEISENIFKKFDIDYATIPYRDQVREQARRRRLEVEKTEP 505

  Fly   642 EK-----RVGGGGFGFYKKMNEGSASKQRHFKQVNRDQAKKFMR 680
            :|     ::....:...|::.|     :|:.::..|...|:|::
pombe   506 KKLARPAKIKNEAWSKQKEVKE-----KRNTRREKRKSKKEFLK 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_524446.3	DEADc_DDX18	198..395	CDD:350700	73/213 (34%)
		SF2_C_DEAD	408..537	CDD:350174	51/131 (39%)
		DUF4217	570..627	CDD:464056	19/60 (32%)
spb4	NP_595956.1	PRK11634	1..>451	CDD:236941	158/464 (34%)
		DEADc_DDX55	12..215	CDD:350718	73/213 (34%)
		tolA_full	<487..>600	CDD:274303	11/63 (17%)