Protein Alignment pit and rde-12

DIOPT Version :9

• Sequence 1: NP_001287459.1
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_001256533.1
• Gene: rde-12 / 179855
• WormBaseID: WBGene00010280
• Length: 959
• Species: Caenorhabditis elegans
• Alignment Length: 672
• Identity: 145/672 - (21%)
• Similarity: 259/672 - (38%)
• Gaps: 167/672 - (24%)

  Fly    14 KREKMKKELSQKKGNKNAQKQEPPKQNGNKPSKKPEKLSKKHVAKDEDDDLEEDFQEAP------ 72
            :.::.::...|..|:...::.:..::|.|..: :|.:.::........|....:.|.:|
 Worm   151 RNDQYRQGSYQGDGHSGYRRDDDRRRNDNDQA-RPYQSNRDSDRNSPRDHHNYNSQSSPRSHQGG 214

  Fly    73 -----LPKKKQQKQPPKKQ----QIQVANS---------DSESDDDEQEDEADEDSDLDEVAEVD 119
                 .||:..|::....|    ..:..||         :..:|...|:|..|..|..:..:...
 Worm   215 QDRYSAPKEDNQRRYDNHQGGHDSYRGQNSGGYSGNNSGEYRNDYRSQQDSRDHRSGGNNSSSGF 279

  Fly   120 EEDVDSGSEDD-------------------------------DQQEDEDEEEPVPAKKTKLLPNK 153
            :.|...|..|:                               |....|....||.|.:..:
 Worm   280 KNDGGFGGNDNRGFGNNGGGSFGNPNNSYRGNSNNIGGFHRSDGSNSEGVNAPVRAPRDWV---- 340

  Fly   154 SKAQNGKPAKDDEPFTVESS--LA--------ALDYR--DSDDRSFASLKGAVSEATLRAIKEMG 206
                  ...:|.:....|::  ||        |::.|  :.|.|..:.....:....|..:|.:.
 Worm   341 ------PVTRDIDELVRETADRLADCDVGQDRAVEIRNAEKDVRLTSWTNSGLHPTILETLKRIK 399

  Fly   207 FTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVELINKLRFMPRN------GTGVIII 265
            :..:..||...:..:|.|.|::|.|:|.:|||.||.:|.::.|.::....||      |...:|:
 Worm   400 YNNVRTIQGAMIPQVLDGHDVLGQAETSAGKTAAFGLPIIDKILRMDEETRNKARQDDGPLALIL 464

  Fly   266 SPTRELSMQTFGVLKELMAHHHHTYGLVMGGSNRQVESEKLGKGINILVATPGRLLDHLQNSPDF 330
            :|||||:.|....|:....:......|..|.|:|.....::..|.:||:.|.||::|....|...
 Worm   465 APTRELAAQIHEALRTYCQNTDIIVLLSYGQSDRARSLNEIRNGCDILIGTCGRIMDFTVKSHIS 529

  Fly   331 LYKNLQCLIIDEVDRIL----------------EIGFEEELKQIINLLPKRRQTMLFSATQTARI 379
            |. :|:.|:.||.||:|                :.||.|.        ...|||::.|||..|.:
 Worm   530 LL-HLRFLVFDEADRLLQDMKKDPLGHLGAIIKDAGFMES--------AATRQTIMTSATFNASV 585

  Fly   380 -----EALSKLALKSEPIYVGVHDNQDTATVDGLEQGYIVCP--SEKRLLVLFTFLKKN---RKK 434
                 |.:.:|..:.|.|.:.:.:.:.:..|: ||  :..|.  :||. ..|...||:|   :..
 Worm   586 MTVANELMKRLPGQDEMIKIVLANGRLSKRVN-LE--FFECKGLAEKN-AKLREILKQNVNGKTL 646

  Fly   435 KVMVFF------SSCMSVKYHHELFNYIDLPVTS-------IHGKQKQTKRTTTFFQFCNAESGI 486
            |.::|.      .:|.:             .:||       :||.:.|..|......|.:....:
 Worm   647 KTIIFVQKKDQCDACAA-------------KLTSGGMLAQTLHGDRSQDMREKLINDFKSNRVNL 698

  Fly   487 LLCTDVAARGLDIPQVDWIVQYDPPD-DPRE----YIHRVGRTAR-GSGTSGHALLLMRPE---- 541
            |:.||:.:||:|:..:|.::.:|.|| ||.:    :|||.|||.| |...:|..:..:.|:
 Worm   699 LVTTDLLSRGIDVSDLDRVINFDLPDGDPDQGADTFIHRAGRTGRTGRKENGLCVSFVDPQSDRD 763

  Fly   542 --------ELGFLRYLKAAKVP 555
                    ||...:.|...|||
 Worm   764 SLLAPKLVELIISQNLPDLKVP 785

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_001287459.1	SrmB	186..677	CDD:223587	110/433 (25%)
		DEADc	187..394	CDD:238167	62/233 (27%)
		HELICc	408..537	CDD:238034	40/152 (26%)
		DUF4217	569..627	CDD:290667
rde-12	NP_001256533.1	PTZ00110	230..799	CDD:240273	134/592 (23%)
		P-loop_NTPase	382..594	CDD:304359	59/220 (27%)
		HELICc	628..755	CDD:238034	37/140 (26%)
		Nucleoporin_FG	<867..950	CDD:290362

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.010