Protein Alignment pit and C24H12.4

DIOPT Version :9

• Sequence 1: NP_001287459.1
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_740966.1
• Gene: C24H12.4 / 173432
• WormBaseID: WBGene00016073
• Length: 634
• Species: Caenorhabditis elegans
• Alignment Length: 722
• Identity: 166/722 - (22%)
• Similarity: 282/722 - (39%)
• Gaps: 183/722 - (25%)

  Fly    48 PEKLSKKHVAKDEDDDLEEDFQEAPLPKKKQQKQPPKKQQIQVANSDSESDDDEQEDEADEDSDL 112
            |::::||.....:       |.|...||   .|:.||||:
 Worm     3 PDEVTKKKRKSVK-------FAEEEPPK---VKEAPKKQK------------------------- 32

  Fly   113 DEVAEVDEEDVDSGSEDDDQQEDEDEEEPVPAKKTKLLPNKSKAQNGKPAKDDEPFTVESSLAAL 177
                        :|.:.:...|..|:.|....:|.|....||:|:..:...:.   .|...:..:
 Worm    33 ------------AGKKIEVSVELRDKNEEKMGRKRKHRMKKSQAEKRQKLMES---LVGPQVDEM 82

  Fly   178 DYRDSDDRSFASLKGAVSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFL 242
            |: :.:.::||..  .:.|..|::|.|:|:.:..::|...::..|:.::::|.|:||||||.|||
 Worm    83 DF-EPEHKTFADF--GLDERILKSIGELGWEKANQVQESVISLALENKNIMGRARTGSGKTGAFL 144

  Fly   243 IPAVELINKLRFMPRN-----GTGVIIISPTRELSMQTFGVLKELMAHHHHTYGLVMGGSNRQVE 302
            ||   |:.||....:.     |...:||:||:||..|.:.:..:|.........:.:...|.:..
 Worm   145 IP---LVQKLIAESKTNDGSVGPSAVIIAPTKELITQIYKLFVKLSQALPFLQAINLCDINEEEN 206

  Fly   303 SEKLGKGINILVATPGRLLDHLQNSPDFLYKNLQC-----LIIDEVDRILEIGFEEELKQIINLL 362
            |..|....:::|.|||:||......|::      |     |::||.|.:|..|:|||:.:|.:.|
 Worm   207 SVWLEDRSHVVVTTPGKLLRMCSLRPEY------CTLVSYLVMDEADLLLSFGYEEEMIKIRSKL 265

  Fly   363 PKRRQTMLFSATQTARIEALSKLALKSEPIYVGVHDNQDTATVDGLEQGYIVCPS-EKRLLVLFT 426
            |...|.::.|||....:..|.||.:....|.:.:.:. |....|.|.|..:.|.| |:|..:|..
 Worm   266 PPTYQCLMTSATLKDDMTTLKKLFMTGPVITIKLTEG-DLPNSDQLTQYQLTCGSDEERFAILVA 329

  Fly   427 FLKK--------------NRKKKVMV----------FFSSCMSVKYHHELFNYID-----LPVTS 462
            ..|.              :|..|:|:          ..:|.|.......:.|..:     :.:.|
 Worm   330 MFKLKLIVGRSILFVNTIDRCYKLMLILRVFGLKSCILNSAMPANSRCHVINQFNEGSYQIVIAS 394

  Fly   463 -------------IHGK--------QKQTKRTTTFFQFCNAESGILLCTDVAARGLDIPQVDWIV 506
                         |.||        :|:.|:.:..    :.|||:       :||:|...|..:|
 Worm   395 DVSDADGSKLKEEIAGKSDEKPEKDEKKGKKASKL----DKESGV-------SRGIDFHHVSNVV 448

  Fly   507 QYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGFLRYLK-------AAKVPLNEFEFSWQ 564
            .:|.|:....|||||||||||. ..|.||....|.|...|..::       ..|| |..:||..:
 Worm   449 NFDFPETTDAYIHRVGRTARGF-NKGTALSFCIPSERAHLEQIQEEINQQMGRKV-LQPYEFRIK 511

  Fly   565 KIADIQLQLEKLIA---KNYFLNQSAKEAFKSYVRAYDSHQLKQIFNVN---------------- 610
            ::....|:..:.::   |........||..:..:|   |..|:..|..|
 Worm   512 ELDTFLLRTREALSKCTKGVIKKARLKEIRQELMR---SANLQTFFAKNEREKLLMQTDCHPVML 573

  Fly   611 TLDLQAVAKSFGFLVPPV---VDLKVGAAKRERPEKRVGGGGFGFYKKMNEGSASKQRH-FKQVN 671
            .::..|:|....::||..   :|.....||..|             ..|.:....|.:| |::..
 Worm   574 KINSPAIADVTSYMVPEALRGMDFSAPGAKNRR-------------YNMGQKHRQKLKHKFQKKG 625

  Fly   672 RDQAKKF 678
            :|..|.|
 Worm   626 KDPLKTF 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_001287459.1	SrmB	186..677	CDD:223587	141/581 (24%)
		DEADc	187..394	CDD:238167	65/216 (30%)
		HELICc	408..537	CDD:238034	44/179 (25%)
		DUF4217	569..627	CDD:290667	12/76 (16%)
C24H12.4	NP_740966.1	SrmB	46..561	CDD:223587	136/546 (25%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D973872at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.010