Protein Alignment pit and B0511.6

DIOPT Version :9

• Sequence 1: NP_001287459.1
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: NP_492779.1
• Gene: B0511.6 / 172954
• WormBaseID: WBGene00015232
• Length: 544
• Species: Caenorhabditis elegans
• Alignment Length: 591
• Identity: 340/591 - (57%)
• Similarity: 427/591 - (72%)
• Gaps: 53/591 - (8%)

  Fly    75 KKKQQKQPPKKQQIQVANSDSESDDDEQEDEADEDSDLDEVAEVDEEDVDSGSEDDDQQEDEDEE 139
            |||..|:..|:.:           |..::.:|.|....:.:.|.|||:|:   |:...|.:|..|
 Worm     6 KKKVLKRKLKQMK-----------DGHEKKKAKEVVVEEPMEEEDEEEVE---EEQKHQTEESSE 56

  Fly   140 EPVPAKKTKLLPNKSKAQNGKPAKDDEPFTVESSLAALDYRDSDDRSFASLKGAVSEATLRAIKE 204
            ..|....||                                    .:||||:|.|:...|:|::.
 Worm    57 TKVSEFLTK------------------------------------TTFASLEGKVNANLLKAVQG 85

  Fly   205 MGFTEMTEIQSKSLTPLLKGRDLVGAAQTGSGKTLAFLIPAVELINKLRFMPRNGTGVIIISPTR 269
            :|||.|||||:||:.|||:|:|::.:|:||||||||||:||:||::||.:...|||||||:||||
 Worm    86 LGFTTMTEIQAKSIDPLLEGKDVLASAKTGSGKTLAFLLPAIELLHKLNWKQHNGTGVIIVSPTR 150

  Fly   270 ELSMQTFGVLKELMAHHHHTYGLVMGGSNRQVESEKLGKGINILVATPGRLLDHLQNSPDFLYKN 334
            ||||||:|||.||:...:.|||||||||||..|.:||.||::|||||||||||||||:.:||.:|
 Worm   151 ELSMQTYGVLSELLEGSNLTYGLVMGGSNRSAEKDKLAKGVSILVATPGRLLDHLQNTDNFLVRN 215

  Fly   335 LQCLIIDEVDRILEIGFEEELKQIINLLPKRRQTMLFSATQTARIEALSKLALKSEPIYVGVHDN 399
            ::||||||.||||:||||.|::|::..|||:||:||||||.:.:::.|.||||.|.|:.|.||:.
 Worm   216 MKCLIIDEADRILDIGFEIEMQQVLRHLPKQRQSMLFSATHSPKVDELVKLALHSNPVRVSVHEK 280

  Fly   400 QDTATVDGLEQGYIVCPSEKRLLVLFTFLKKNRKKKVMVFFSSCMSVKYHHELFNYIDLPVTSIH 464
            .:.|||:||:|||||.||:||||:||||||||:.||||||||||.|||:||||.||||:|..|||
 Worm   281 AEEATVEGLQQGYIVAPSDKRLLLLFTFLKKNKTKKVMVFFSSCNSVKFHHELLNYIDIPCMSIH 345

  Fly   465 GKQKQTKRTTTFFQFCNAESGILLCTDVAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSG 529
            |||||.||||||||||.||:||||||||||||||||.|||||||||.|:||||||||||||||:.
 Worm   346 GKQKQQKRTTTFFQFCQAETGILLCTDVAARGLDIPAVDWIVQYDPTDEPREYIHRVGRTARGTN 410

  Fly   530 TSGHALLLMRPEELGFLRYLKAAKVPLNEFEFSWQKIADIQLQLEKLIAKNYFLNQSAKEAFKSY 594
            .||.|||::||||||||||||||||.||||||||.|:|:||.|||.||:|||:||:|||||:|.|
 Worm   411 GSGKALLVLRPEELGFLRYLKAAKVTLNEFEFSWSKVANIQSQLENLISKNYYLNKSAKEAYKCY 475

  Fly   595 VRAYDSHQLKQIFNVNTLDLQAVAKSFGFLVPPVVDLKVGAAKRERPEKRVGGGGFGFYKKMNEG 659
            :||||||.||.||:|..:||.||:|||||.|||.|||.:....:.....::.|.|   |:|..:.
 Worm   476 LRAYDSHSLKDIFDVTNMDLTAVSKSFGFSVPPFVDLPISNKPKVEIRSKLSGAG---YRKKKQS 537

  Fly   660 SASKQR 665
            ...|.:
 Worm   538 FTFKAK 543

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_001287459.1	SrmB	186..677	CDD:223587	320/480 (67%)
		DEADc	187..394	CDD:238167	130/206 (63%)
		HELICc	408..537	CDD:238034	106/128 (83%)
		DUF4217	569..627	CDD:290667	40/57 (70%)
B0511.6	NP_492779.1	DEADc	68..276	CDD:238167	130/207 (63%)
		DEXDc	83..291	CDD:214692	130/207 (63%)
		Helicase_C	312..407	CDD:278689	80/94 (85%)
		DUF4217	450..508	CDD:290667	40/57 (70%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160158890
Domainoid	1	1.000	234	1.000	Domainoid score	I1348
eggNOG	1	0.900	-	-		E2759_KOG0342
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H6697
Inparanoid	1	1.050	656	1.000	Inparanoid score	I412
Isobase	1	0.950	-	0	Normalized mean entropy	S302
OMA	1	1.010	-	-		QHG53700
OrthoDB	1	1.010	-	-		D218522at33208
OrthoFinder	1	1.000	-	-		FOG0003394
OrthoInspector	1	1.000	-	-		oto17676
orthoMCL	1	0.900	-	-		OOG6_102072
Panther	1	1.100	-	-	LDO	PTHR24031
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R549
SonicParanoid	1	1.000	-	-		X2746
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	16.790