Protein Alignment pit and Rs1

DIOPT Version :10

• Sequence 1: NP_524446.3
• Gene: pit / 42595
• FlyBaseID: FBgn0266581
• Length: 680
• Species: Drosophila melanogaster
• Sequence 2: XP_061517461.1
• Gene: Rs1 / 1270844
• VectorBaseID: AGAMI1_014052
• Length: 897
• Species: Anopheles gambiae
• Alignment Length: 771
• Identity: 210/771 - (27%)
• Similarity: 354/771 - (45%)
• Gaps: 133/771 - (17%)

  Fly    18 MKKELSQKKGNKN---------AQKQEPPKQNGNKPSKKPEKLSKK-HVAKDEDDDLE-EDFQEA 71
            |||:..||...||         |........||.....:.|||:.: ...|..:||.| ||..|.
Mosquito     1 MKKDKKQKVAEKNKANGATAAAAGAATDDAVNGENGVVESEKLTHQLDFMKTLEDDAEVEDLSEE 65

  Fly    72 PLPKKKQQKQPPKKQQI-------QVANSDSESDDDEQED------EADEDSDLDEVAEV----D 119
            ...:.:.|....|.|::       |..:|..|.:.|..:|      ..:.....|::|.|    .
Mosquito    66 SETEIEYQPTKQKNQKLTDFDGGFQFVSSVKEYNHDTWDDLMKFVKRKNRGEVNDKIANVIRDRT 130

  Fly   120 EEDVDSGSEDDDQQEDED-----EEE-------------PVPAKKTKLLPNKSKAQNGKPA---- 162
            :|:.|: .:|||::|||:     .||             .|..:|.|.|   ::|:||.|.
Mosquito   131 KENADA-LKDDDEEEDEEGNRAYNEEVDLSDDELKHDYMRVKERKGKKL---TEAENGGPTVEVK 191

  Fly   163 KDDEPFTVESSLAALDYR-DSDDRSFASLKGAVSEATLRAIKEMGFTEMTEIQSKSLTPLLKGRD 226
            :|.|..|.|.....::.. :.:.:||..:.  :|...::||..:|:...|.||:.::...|.|||
Mosquito   192 EDTEDGTKEDYFEEIEENANGEIQSFYQMD--LSRPLMKAIGALGYIYPTPIQASTIPIALMGRD 254

  Fly   227 LVGAAQTGSGKTLAFLIPAVELINKLRFMPRNG---TGVIIISPTRELSMQTFGVLKELMAHHHH 288
            :.|.|.||:|||.|:::|.:|   :|.:.|...   |.|:::.|||||..|.:.|.|:|....:.
Mosquito   255 ICGCAATGTGKTAAYMLPTIE---RLLYKPNVAQAVTRVLVLVPTRELGAQVYQVAKQLTQFTNV 316

  Fly   289 TYGLVMGGSNRQVESEKLGKGINILVATPGRLLDHLQNSPDFLYKNLQCLIIDEVDRILEIGFEE 353
            ..|:.:||.:.:.:...|.|..::::||||||:||::|:|.|...:::.||:||.||:|:..|.|
Mosquito   317 DVGIAIGGLDVKAQEAVLRKNPDVVIATPGRLIDHIKNTPSFSLDSIEILILDEADRMLDEYFAE 381

  Fly   354 ELKQIINLLPKRRQTMLFSATQTARIEALSKLALKSEPIYVGVHDNQDTATVDGLEQGYIVCPSE 418
            ::|:||......|||||||||.|..::.|:.::|| :|:.:.|::||..|.  .|.|.:|.....
Mosquito   382 QMKEIIRSCSATRQTMLFSATMTEEVKDLAAVSLK-KPVKIFVNNNQTVAF--NLRQEFIRIREG 443

  Fly   419 K---RLLVLFTFLKKNRKKKVMVFFSSCMSVKYHHELFNYIDLPVTSIHGKQKQTKRTTTFFQFC 480
            :   |..:|...:.:......|||..:..:......|...:.:....:||...|.:|..:..:|.
Mosquito   444 READREAILAALVCRTFHDHCMVFVQTKRTAHRLRILLGLLGVKTGELHGDLTQAQRLESLKEFK 508

  Fly   481 NAESGILLCTDVAARGLDIPQVDWIVQYDPPDDPREYIHRVGRTARGSGTSGHALLLMRPEELGF 545
            :.:..||:.||||||||||..|..::.:..|.....|||||||||| :|.:|.::.|...:|...
Mosquito   509 DEQVDILIATDVAARGLDISTVKTVINFVMPATLEHYIHRVGRTAR-AGKAGVSVSLAGEQERKI 572

  Fly   546 LRYL--------KAAKVPLNEFEFSWQKIADIQLQLEKLIAKNYFLNQSAKEAFKSYVRAYDSHQ 602
            ::.:        |...:||:..|....|:|.::.::::::|:     :.|::..:...:...|.:
Mosquito   573 VKEIVKNAVSSVKNRIIPLDIIEKYRNKVAALEPEIDRVLAE-----ERAEKLLRQTEQQLTSAE 632

  Fly   603 LKQIFNVNTLDLQAVAKSFGFLVPP---------------------VVDLKVGAAKRER------ 640
            .|.:.|......|.:.       ||                     ..:.|..|.||:|
Mosquito   633 RKLLGNAGKAAKQDIP-------PPREWFQTQHERREEKNRLAGEEQGEKKKAAKKRKRRDDDDE 690

  Fly   641 ---------PEKR------VGGGGFGFYKK-MNEGSASKQRHFKQVNRDQAKKFMR 680
                     .|||      .|||.....|| ..:.:|...:..||:.|::|.:.:|
Mosquito   691 EDFDPVRYHEEKRKQQKAAAGGGAVNSKKKSKTDANADANKTAKQLARERALEEVR 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
pit	NP_524446.3	DEADc_DDX18	198..395	CDD:350700	75/199 (38%)
		SF2_C_DEAD	408..537	CDD:350174	40/131 (31%)
		DUF4217	570..627	CDD:464056	6/56 (11%)
Rs1	XP_061517461.1	None