DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Fadd and Fadd

DIOPT Version :9

Sequence 1:	NP_651006.1	Gene:	Fadd / 42594	FlyBaseID:	FBgn0038928	Length:	239	Species:	Drosophila melanogaster
Sequence 2:	NP_034305.1	Gene:	Fadd / 14082	MGIID:	109324	Length:	205	Species:	Mus musculus

Alignment Length:	210	Identity:	46/210 - (21%)
Similarity:	85/210 - (40%)	Gaps:	52/210 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 QLKLIFVEEIGSRRRSDCIRTIEDLIDCLERADELSEYNVEPLRRISGNMPQLIEALSAYTKPEN 90
            :||.:..|.: |:|:.:.:::..||...|...::|.       |..:|.:.:|:.:|..:
Mouse    22 ELKFLCRERV-SKRKLERVQSGLDLFTVLLEQNDLE-------RGHTGLLRELLASLRRH----- 73

  Fly    91 ILGHPVNLYQELRLAEELRQQLRIAPASQNAQPSVSELAAAVPPTAIQNYATPAAFTDHKRTMVF 155
                  :|.|.|...|        |..:..|.|..::|..|                       |
Mouse    74 ------DLLQRLDDFE--------AGTATAAPPGEADLQVA-----------------------F 101

  Fly   156 KKISEELGRYWRRLGRSAGIGEGQMDTIEERYPHDLKSQILRLLQLIEEDDCHDPKHFLLRLCRA 220
            ..:.:.:||.|:||.|...:.|.:||.|||:||..|..::...|::.:..:..:..  :..|.:|
Mouse   102 DIVCDNVGRDWKRLARELKVSEAKMDGIEEKYPRSLSERVRESLKVWKNAEKKNAS--VAGLVKA 164

  Fly   221 LGDCGRNDLRKRVEQ 235
            |..|..|.:...||:
Mouse   165 LRTCRLNLVADLVEE 179

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Fadd	NP_651006.1	DD	22..>71	CDD:301326	10/44 (23%)
Fadd	NP_651006.1	Death	154..234	CDD:260017	22/79 (28%)
Fadd	NP_034305.1	DED_FADD	2..83	CDD:260043	13/60 (22%)
		Death_FADD	97..181	CDD:260020	18/83 (22%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	181..205		5/23 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	44	1.000	Domainoid score	I12263
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0008143
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR15077
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010