Protein Alignment CG6015 and Cdc40

DIOPT Version :10

• Sequence 1: NP_651005.1
• Gene: CG6015 / 42593
• FlyBaseID: FBgn0038927
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001381149.1
• Gene: Cdc40 / 361859
• RGDID: 1307063
• Length: 579
• Species: Rattus norvegicus
• Alignment Length: 577
• Identity: 355/577 - (61%)
• Similarity: 446/577 - (77%)
• Gaps: 14/577 - (2%)

  Fly     6 SYASSSDEESDHADAATATTNSEPS-APIP--DHLLPVDKTHSL--SKSIAVCAAPTVVPLGASA 65
            ||.|.|..|||        ::||.| .|:|  |.|:.:.|:.|.  |.::||.:||.|.......
  Rat    11 SYGSGSGSESD--------SDSEGSRCPLPAADSLMHLTKSPSAKPSLTVAVDSAPEVAVKEDLE 67

  Fly    66 VPRTLDPTLKEVTYNPRYEEMYAPVKGPEHPDLTMQQRAPRNTLAGYVEKAHINAFEFENQRRTF 130
            ....|||.:|||.|||.||.|:||..|||:|..|.|..||||.|:||.|.||||.|.||.|||||
  Rat    68 TGVHLDPAVKEVQYNPTYETMFAPEFGPENPFRTQQMAAPRNMLSGYAEPAHINDFMFEQQRRTF 132

  Fly   131 HTYGYALDPSVDDQADGQSFVGDLQSAYDDNGKTVFEPPKAK-KLRKQEKNDNPEDIEGFLGPWG 194
            .|||||||||:|:......::|.::.|..:.|.||||..:.| :.||:.|.::..:|:||||||.
  Rat   133 ATYGYALDPSLDNHQVSAKYIGSVEDAEKNQGLTVFETGQKKTEKRKKFKENDASNIDGFLGPWA 197

  Fly   195 KFENEVSVAKPNEQERAELDELLSKRHKRGRIPEDKPLEEKSTLHIKDAYDYQGRSYLHAPHDLG 259
            |:.:|..||||:|:|:.||||:.:||.|:|:..|:||.|||:.||:|:.||||||||||.|.|:|
  Rat   198 KYVDEKDVAKPSEEEQKELDEITAKRQKKGKQEEEKPGEEKTILHVKEMYDYQGRSYLHIPQDVG 262

  Fly   260 VNLRSNAPPTKCFLPKAHIHTWSGHNKGISSIRWFPKTAHLLLSGSMDCRVKLWEVYGERRCIRT 324
            |||||:.||.||:|||..||.||||.||:|::|.||.:.|||||.||||::|||||||:|||:||
  Rat   263 VNLRSSVPPEKCYLPKKQIHVWSGHTKGVSAVRLFPLSGHLLLSCSMDCKIKLWEVYGDRRCLRT 327

  Fly   325 FSGHRQAIKDIAWNNRGTNFLSASYDRYIKLWDAETGDVVSRFTTRKMPFCVKFHPDNSKQHLFV 389
            |.||.:|::||.:|..||.||||:||||:||||.|||..:||||.||:|:||||:||..||:|||
  Rat   328 FIGHSKAVRDICFNTAGTQFLSAAYDRYLKLWDTETGQCISRFTNRKVPYCVKFNPDEDKQNLFV 392

  Fly   390 AGTSDKKIICWDTRSGDIVQEYDRHLGSVSTITFVDDNRRFVTTSDDKSMRIWEWDIPVDMKYIA 454
            ||.|||||:.||.|||:||||||||||:|:||.|||:|||||:||||||:|:||||||||.||||
  Rat   393 AGMSDKKIVQWDIRSGEIVQEYDRHLGAVNTIVFVDENRRFVSTSDDKSLRVWEWDIPVDFKYIA 457

  Fly   455 DPTMHSMPAVTLAPNGKWMACQSLDNKIVIFSALNRFKMNRKKTFTGHMVSGYACQLDFSPDMSY 519
            :|:|||||||||:|||||:||||:||:|:||.|.|||::|:||.|.||||:|||||:||||||||
  Rat   458 EPSMHSMPAVTLSPNGKWLACQSMDNQILIFGAQNRFRLNKKKIFKGHMVAGYACQVDFSPDMSY 522

  Fly   520 LVSGDGDGKCYIWDWKTTKMYKKWQAHDGVCISALWHPHEASKVVTAGWDGQIKYWD 576
            ::||||:||..||||||||:|.:::|||.|||.|:|||||.|||:|.||||.||.||
  Rat   523 VISGDGNGKLNIWDWKTTKLYSRFKAHDKVCIGAVWHPHETSKVITCGWDGLIKLWD 579

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6015	NP_651005.1	WD40	277..576	CDD:238121	213/298 (71%)
		WD40 repeat	289..327	CDD:293791	26/37 (70%)
		WD40 repeat	332..368	CDD:293791	22/35 (63%)
		WD40 repeat	374..412	CDD:293791	27/37 (73%)
		WD40 repeat	418..453	CDD:293791	27/34 (79%)
		WD40 repeat	461..500	CDD:293791	27/38 (71%)
		WD40 repeat	509..532	CDD:293791	16/22 (73%)
Cdc40	NP_001381149.1	WD40	281..579	CDD:238121	213/297 (72%)
		WD40 repeat	292..330	CDD:293791	26/37 (70%)
		WD40 repeat	335..371	CDD:293791	22/35 (63%)
		WD40 repeat	377..415	CDD:293791	27/37 (73%)
		WD40 repeat	421..503	CDD:293791	61/81 (75%)
		WD40 repeat	511..547	CDD:293791	26/35 (74%)
		WD40 repeat	553..578	CDD:293791	18/24 (75%)