Protein Alignment CG6015 and Wdr25

DIOPT Version :9

• Sequence 1: NP_651005.1
• Gene: CG6015 / 42593
• FlyBaseID: FBgn0038927
• Length: 576
• Species: Drosophila melanogaster
• Sequence 2: NP_001129366.1
• Gene: Wdr25 / 314443
• RGDID: 1562505
• Length: 533
• Species: Rattus norvegicus
• Alignment Length: 509
• Identity: 136/509 - (26%)
• Similarity: 214/509 - (42%)
• Gaps: 96/509 - (18%)

  Fly    89 PVKGPEHPDLTMQQRAPRNTLAGYVEKAHINAFEFENQRRTFHTYGYALDPSVDDQADGQSFVGD 153
            |...|..|.|.| .|||    .|:|..|   |..|:..:..:.    |..|| ...:..:|..|:
  Rat    98 PTSEPPGPSLWM-NRAP----VGHVPLA---AACFKPLKPAWD----AFTPS-HTHSKLESTAGN 149

  Fly   154 LQSAYDDNGKTVFEPPKAKKLRKQEKNDNPE-----DIEGFLGPWGKFENEVSVAKPNEQERAEL 213
            ..|:....|:....|...|:|| |.:..|||     |:|....|.|.....:.|| |...|  .:
  Rat   150 ASSSQRKRGEACVLPYIPKRLR-QLQVLNPEATGGRDVEPPGSPAGCAPAPLCVA-PTVSE--FI 210

  Fly   214 DELLSKRHKRGRIPEDKPLEEKSTLHIKDAYDYQGRSYLHAPHDLGVNLRSNAPPTKCFLPKAHI 278
            ...|:.:::...:|      :|...|::
  Rat   211 QPYLNSQYRETTVP------KKVLFHLR------------------------------------- 232

  Fly   279 HTWSGHNKGISSIRWFP--KTAHLLLSGSMDCRVKLWEVYGERRCIRTFSGHRQAIKDIAWNNRG 341
                ||...::||:|.|  ..:|:|||.|||...|:|.......|::|:|.|.:|::...|:..|
  Rat   233 ----GHRGPVNSIQWCPVFSKSHMLLSASMDKTFKVWNAVDSGHCLQTYSVHSEAVRAARWSPCG 293

  Fly   342 TNFLSASYDRYIKLWDAETGDVV------SRFTTRKMPFCVKFHPDNSKQH-LFVAGTSDKKIIC 399
            ...||..:|..:.|.|.|||..|      .|.||      :||||   |.| :|:.|....:|..
  Rat   294 RRILSGGFDFALHLTDLETGTQVFSGHSDFRVTT------LKFHP---KDHNVFLCGGFSSEIKA 349

  Fly   400 WDTRSGDIVQEYDRHLGSVSTITFVDDNRRFVTTSD----DKSMR-IWEWDIPVDMKYIADPTMH 459
            ||.|:|.:|:.|...:.....|.|:.:...|::::|    |.:.| |..||.....| |::...|
  Rat   350 WDMRTGKVVKGYKATIQQTLDILFLQEGSEFLSSTDASTRDSADRTIIAWDFRTAAK-ISNQIFH 413

  Fly   460 ---SMPAVTLAPNGKWMACQSLDNKIVIFSALNRFKMNRKKTFTGHMVSGYACQLDFSPDMSYLV 521
               :.|::.|.|.......|:..|.:.:||::..::|:|::.:.||.|.|||...:.||....||
  Rat   414 ERYTCPSLALHPREPVFLAQTNGNYLALFSSVWPYRMSRRRRYEGHKVEGYAVGCECSPCGDLLV 478

  Fly   522 SGDGDGKCYIWDWKTTKMYKKWQAHDGVCISALWHPHEASKVVTAGWDGQIKYW 575
            :|..||:..::.::|.......|.|...|:...:||...|.:.|..|.|.||.|
  Rat   479 TGSADGRVLMFSFRTASRACTLQGHTQACLGTTYHPVLPSVLGTCSWGGDIKIW 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6015	NP_651005.1	WD40	<274..576	CDD:225201	96/319 (30%)
		WD40	277..576	CDD:238121	96/316 (30%)
		WD40 repeat	289..327	CDD:293791	15/39 (38%)
		WD40 repeat	332..368	CDD:293791	12/41 (29%)
		WD40 repeat	374..412	CDD:293791	14/38 (37%)
		WD40 repeat	418..453	CDD:293791	10/39 (26%)
		WD40 repeat	461..500	CDD:293791	9/38 (24%)
		WD40 repeat	509..532	CDD:293791	7/22 (32%)
Wdr25	NP_001129366.1	WD40	228..532	CDD:238121	96/354 (27%)
		WD40 repeat	240..279	CDD:293791	15/38 (39%)
		WD40 repeat	285..319	CDD:293791	11/33 (33%)
		WD40 repeat	325..362	CDD:293791	16/45 (36%)
		WD40 repeat	369..411	CDD:293791	11/42 (26%)
		WD40 repeat	418..457	CDD:293791	9/38 (24%)
		WD40 repeat	465..501	CDD:293791	9/35 (26%)
		WD40 repeat	507..532	CDD:293791	9/24 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0282
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810