Protein Alignment CG13409 and tmem181

DIOPT Version :10

• Sequence 1: NP_651004.1
• Gene: CG13409 / 42592
• FlyBaseID: FBgn0038926
• Length: 547
• Species: Drosophila melanogaster
• Sequence 2: NP_001039119.2
• Gene: tmem181 / 733940
• XenbaseID: XB-GENE-5837127
• Length: 517
• Species: Xenopus tropicalis
• Alignment Length: 533
• Identity: 250/533 - (46%)
• Similarity: 348/533 - (65%)
• Gaps: 43/533 - (8%)

  Fly    33 SQFSDLFSDFSRYISPAYHH----------DRCERSVHMRLYSMHKREFVMVFLGFFTCFGLGIV 87
            |...:.|.||.:.||.||:.          ||..|...||||::.||.||:||:.||.||||.:.
 Frog    10 SSLCNEFKDFCKKISDAYNELKEDLTPYRDDRFYRLAPMRLYTLSKRHFVLVFVVFFICFGLTLF 74

  Fly    88 IGLTGPPITSTSSLTAQQILANTSLAHSPTVLGKGPFAMKSPLTTTYSQQMWLIAKLVTDNNDDE 152
            ||:.||.:...:| |..:::..:.:         .||.:.||:.:||:||:||..::..|..||.
 Frog    75 IGIAGPNVIQANS-TGYEVINKSKV---------DPFKLNSPVLSTYNQQLWLTCRIDLDKADDF 129

  Fly   153 RYDKSFQVSVSIDGINEQHKPQSVLG--SGVAHNRTRHLVCVRNDCEEFTVMHLGFLDYAHYIIT 215
            ....:|.::|.|.|:.    |.:.:.  |...|.|.|.:.|.:. |||..|:|||:|:|..|.:.
 Frog   130 SIQTNFTMTVQIHGVT----PDATVTFISSPEHTRPRTIRCAQK-CEEIIVVHLGYLNYTQYKLL 189

  Fly   216 VRFYGLESFHQKYNIRSITFYFKTYSPDFTQIEIWFRCIFLLFTFIVICWYAHTLRKYPIYDWSI 280
            |.|..|    ::.:|:::||.:|||||.|:|:|||||.:|::.||:|.|.:||:|||:.:.||.|
 Frog   190 VSFENL----KQLSIKTVTFTWKTYSPTFSQVEIWFRFVFVVLTFMVTCLFAHSLRKFSMRDWGI 250

  Fly   281 EQRWLSVLLPLLLLYDNPFFPLIFLMNSWLPGMLDAILQATFLCALLMFWLCIYHGLR-QNERSF 344
            ||:|:|:||||||||::|||||.||:|||.|||||.:.|:.||||||:||||:|||:| |.||..
 Frog   251 EQKWMSLLLPLLLLYNDPFFPLTFLVNSWFPGMLDDLFQSLFLCALLLFWLCVYHGIRVQGERKC 315

  Fly   345 VRFYLVKVIVVLPIWLCAIVLATWEKCNELRDPTYSHFVDTKNYNGFKMFFYIACCMYVLYLVLL 409
            :.|||.|:::|..:||.::.|..|:..|||.||||.:.||..|:.|.|:||.|...:|:|||:.|
 Frog   316 LTFYLPKLLIVGLLWLASVTLGIWQTVNELHDPTYQYKVDIGNFQGMKIFFLIVASLYILYLLFL 380

  Fly   410 LLRAYTELRSMPYFDMRLKFLTLLMLFVLSISITVTTCRFGFGILEDNFVASLNTTYRSSAQFMC 474
            ::||.||||:|||.|:||||||.|...||.|||.:...|||..:|:|||||.|.|.|.:||:|:.
 Frog   381 IIRACTELRNMPYVDLRLKFLTALTFVVLIISIVILYLRFGAQVLQDNFVAELTTHYENSAEFLS 445

  Fly   475 FYGLLNFYLYTMAYVYSPD-GRFAQAELAVTKDNPAISMIDDSDEDVVYGSDEESRRPLTSVGGG 538
            |||||||||||:|:||||. ....:::|   |||||.||::|||:||:||||.| ..||.:  |.
 Frog   446 FYGLLNFYLYTLAFVYSPSKNALYESQL---KDNPAFSMLNDSDDDVIYGSDYE-EMPLQN--GQ 504

  Fly   539 AGKNDY----DSD 547
            |.:..|    |||
 Frog   505 AIRAKYKAESDSD 517

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13409	NP_651004.1	MIG-14_Wnt-bd	195..492	CDD:461980	166/297 (56%)
tmem181	NP_001039119.2	MIG-14_Wnt-bd	169..465	CDD:461980	168/300 (56%)