Protein Alignment CG13409 and tmem181

DIOPT Version :10

• Sequence 1: NP_651004.1
• Gene: CG13409 / 42592
• FlyBaseID: FBgn0038926
• Length: 547
• Species: Drosophila melanogaster
• Sequence 2: XP_005168570.1
• Gene: tmem181 / 557799
• ZFINID: ZDB-GENE-060503-309
• Length: 530
• Species: Danio rerio
• Alignment Length: 534
• Identity: 253/534 - (47%)
• Similarity: 350/534 - (65%)
• Gaps: 28/534 - (5%)

  Fly    24 LLLRLKSSLSQFSDLFSDFSRYISPAYHHDRCERSVHMRLYSMHKREFVMVFLGFFTCFGLGIVI 88
            |:..:|......::..::....::| |.::|..|...||||::.||.||:||:.||.||||..:|
Zfish    15 LVGEMKRFCRNITEACNELKEELTP-YRNERFYRLAPMRLYTLSKRHFVLVFVVFFFCFGLSTLI 78

  Fly    89 GLTGPPITSTSSLTAQQILANTSLAHSPTVLGKGPFAMKSPLTTTYSQQMWLIAKLVTDNNDDER 153
            ||:||.|.|.:..        ..|:.||.....||||..||..:.|:||:||...:...||..:.
Zfish    79 GLSGPKIISENHY--------NGLSVSPNGSKIGPFAFSSPPLSNYNQQLWLTCIIELQNNIVDL 135

  Fly   154 YDKSFQVSVSIDGINEQHKPQSVLGSGVAHNRTRHLVCVRND--CEEFTVMHLGFLDYAHYIITV 216
            ..:.|.::|.:.|:.:......:  |...|||.|.|.|..:.  |:|..|:|||:|:|..|.|.|
Zfish   136 SWREFGMNVELQGVVQDTSVMRI--SDNVHNRNRSLHCSAHQQACDEIIVLHLGYLNYTQYKINV 198

  Fly   217 RFYGLESFHQKYNIRSITFYFKTYSPDFTQIEIWFRCIFLLFTFIVICWYAHTLRKYPIYDWSIE 281
            .|..|:. ..|.||:::||.||.|...|:|:|||||.:|::.||||.|.:||:|||:.:.||.||
Zfish   199 SFRNLQD-DLKDNIKNVTFVFKMYQDTFSQMEIWFRFVFVVMTFIVTCMFAHSLRKFSMRDWGIE 262

  Fly   282 QRWLSVLLPLLLLYDNPFFPLIFLMNSWLPGMLDAILQATFLCALLMFWLCIYHGLR-QNERSFV 345
            |:|:|:||||||||::|||||.||:|||.||.|||.|||.||||||:||||:|||:| |.||.|:
Zfish   263 QKWMSILLPLLLLYNDPFFPLSFLVNSWFPGTLDAFLQAVFLCALLLFWLCVYHGIRVQGERRFL 327

  Fly   346 RFYLVKVIVVLPIWLCAIVLATWEKCNELRDPTYSHFVDTKNYNGFKMFFYIACCMYVLYLVLLL 410
            .|||.|:::|..:||.|:.|..|:..|||:||||.:.||.:|:.|.|:||.:..|:||||||.|:
Zfish   328 TFYLPKLLMVGLLWLSAVTLGIWQTVNELQDPTYQYKVDIQNFQGMKIFFLLVVCVYVLYLVFLV 392

  Fly   411 LRAYTELRSMPYFDMRLKFLTLLMLFVLSISITVTTCRFGFGILEDNFVASLNTTYRSSAQFMCF 475
            :||.:||::|||.|:||||||.|.|.||.||:.:...|||...|:|||||.|:|.|::||:|:.|
Zfish   393 VRACSELKNMPYSDLRLKFLTALTLVVLVISVIILYLRFGSKALQDNFVAELSTHYQNSAEFLSF 457

  Fly   476 YGLLNFYLYTMAYVYSPD-GRFAQAELAVTKDNPAISMIDDSDEDVVYGSDEESRRPLTSVGGGA 539
            ||||||||||:|:||||. .....::|   |||||.||::|||::|:||||.| ..||.:  |.|
Zfish   458 YGLLNFYLYTLAFVYSPSKNALYDSQL---KDNPAFSMLNDSDDEVIYGSDYE-EMPLQN--GRA 516

  Fly   540 GK------NDYDSD 547
            .|      ::.|||
Zfish   517 IKATAKYQDESDSD 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13409	NP_651004.1	MIG-14_Wnt-bd	195..492	CDD:461980	171/299 (57%)
tmem181	XP_005168570.1	MIG-14_Wnt-bd	178..476	CDD:461980	173/298 (58%)