Protein Alignment CG13409 and Tmem181

DIOPT Version :10

• Sequence 1: NP_651004.1
• Gene: CG13409 / 42592
• FlyBaseID: FBgn0038926
• Length: 547
• Species: Drosophila melanogaster
• Sequence 2: XP_038944147.1
• Gene: Tmem181 / 502228
• RGDID: 1566403
• Length: 516
• Species: Rattus norvegicus
• Alignment Length: 538
• Identity: 245/538 - (45%)
• Similarity: 345/538 - (64%)
• Gaps: 34/538 - (6%)

  Fly    16 AYQLPSGGLLLRLKSSLSQFSDLFSDFSRYISPAYHHDRCERSVHMRLYSMHKREFVMVFLGFFT 80
            |::.|   |...||....:..:.:.:....::| :..||..|...||||::.||.||:||:.||.
  Rat     7 AFEPP---LCSGLKQLCRRLQEAYRELKEDLAP-FKDDRYYRLAPMRLYTLSKRHFVLVFVVFFI 67

  Fly    81 CFGLGIVIGLTGPPITSTSSLTAQQILANTSLAHSPTVLGKGPFAMKSPLTTTYSQQMWLIAKLV 145
            ||||.:.:|:.||.:..||:       ||.||.:|..:   .|..::|...:||:||:||...:.
  Rat    68 CFGLTVFVGIEGPRVIQTSA-------ANFSLNNSKKL---KPVQIRSNPLSTYNQQLWLTCVVE 122

  Fly   146 TDNNDDERYDKSFQVSVSIDGINEQHKPQSVLGSGVAHNRTRHLVCVRNDCEEFTVMHLGFLDYA 210
            .:.:::.....||.::|.:||:::......:  ....|||||.|.|. ..|.|..|.|||:|:|.
  Rat   123 LEPSEETSIQTSFPMTVKVDGVSQDATTMYI--HNKVHNRTRTLTCA-GKCAEIIVAHLGYLNYT 184

  Fly   211 HYIITVRFYGLESFHQKYNIRSITFYFKTYSPDFTQIEIWFRCIFLLFTFIVICWYAHTLRKYPI 275
            .|.:||   |.|..:|.  |:.:.|.:|||:|.|:|:|||||.:|::.||||||.:.|:|||:.:
  Rat   185 QYRVTV---GFEHLNQP--IKEMNFTWKTYNPAFSQLEIWFRFVFVVLTFIVICLFVHSLRKFSM 244

  Fly   276 YDWSIEQRWLSVLLPLLLLYDNPFFPLIFLMNSWLPGMLDAILQATFLCALLMFWLCIYHGLR-Q 339
            .||.|||:|:||||.|||||::|||||.||:|||.|||||...|:.||||||:||||:|||:| |
  Rat   245 RDWGIEQKWMSVLLLLLLLYNDPFFPLSFLVNSWFPGMLDDFFQSLFLCALLLFWLCVYHGIRVQ 309

  Fly   340 NERSFVRFYLVKVIVVLPIWLCAIVLATWEKCNELRDPTYSHFVDTKNYNGFKMFFYIACCMYVL 404
            .||..:.|||.|..:|..:||.::.|..|:..|||.||.|.:.|||.|:.|.|:||.:...:|:|
  Rat   310 GERKCLTFYLPKFFIVGLLWLASVTLGIWQTFNELNDPMYQYRVDTGNFQGMKVFFMVVAAVYIL 374

  Fly   405 YLVLLLLRAYTELRSMPYFDMRLKFLTLLMLFVLSISITVTTCRFGFGILEDNFVASLNTTYRSS 469
            ||:.|::||.:|||.|||.|:||||||.|...||.|||.:...|||..:|:|||||.|:..|::|
  Rat   375 YLLFLIVRACSELRHMPYVDLRLKFLTALTFVVLVISIVILYLRFGAQVLQDNFVAELSAHYQNS 439

  Fly   470 AQFMCFYGLLNFYLYTMAYVYSPD-GRFAQAELAVTKDNPAISMIDDSDEDVVYGSDEESRRPLT 533
            |:|:.|||||||||||:|:||||. ....:::|   |||||.||::|||:||:||||.| ..||.
  Rat   440 AEFLSFYGLLNFYLYTLAFVYSPSKNALYESQL---KDNPAFSMLNDSDDDVIYGSDYE-EMPLQ 500

  Fly   534 SVGGGA----GKNDYDSD 547
            :  |.|    .:.:.|||
  Rat   501 N--GQAIRAKCREESDSD 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG13409	NP_651004.1	MIG-14_Wnt-bd	195..492	CDD:461980	163/297 (55%)
Tmem181	XP_038944147.1	MIG-14_Wnt-bd	169..464	CDD:461980	165/299 (55%)