Protein Alignment Cchl and Hccs

DIOPT Version :10

• Sequence 1: NP_651003.1
• Gene: Cchl / 42590
• FlyBaseID: FBgn0038925
• Length: 281
• Species: Drosophila melanogaster
• Sequence 2: NP_032248.3
• Gene: Hccs / 15159
• MGIID: 106911
• Length: 272
• Species: Mus musculus
• Alignment Length: 273
• Identity: 152/273 - (55%)
• Similarity: 185/273 - (67%)
• Gaps: 26/273 - (9%)

  Fly    11 MEATKSVP---VDHAKYMSGSGAPPPE-CPMH--QKHG-----------DAKSASAVPPH-PKMQ 57
            |.|:.|.|   |:.:....|..|.||. ||||  |:.|           ....|..||.| .:..
Mouse     1 MGASASSPATAVNASNASDGQPASPPSGCPMHKGQRKGCPVTAATSDLTSESKAHTVPAHQDRAY 65

  Fly    58 AASECPV----QHDNSDVNPLNMMPPANQQPAADQPFPLPTDRQTSTIPKVTEDGSVQFWQYPSQ 118
            ...||||    ..|...::|.|:|||.||.|:.||||.|.|.|:.|:||:.   .|.:.|.|||:
Mouse    66 DYVECPVTGARAKDKESLDPSNLMPPPNQTPSPDQPFTLSTSREESSIPRA---DSEKKWVYPSE 127

  Fly   119 QMFWNAMLRKGWRWKTEDVSQKDMGDIIRIHNANNEQAWQEVLKWEALHAKECG-NPRLKSFGGK 182
            ||||||||||||:||.:|:|||||.:||||||.||||||:|:||||||||.||. .|.|..||||
Mouse   128 QMFWNAMLRKGWKWKDDDISQKDMYNIIRIHNQNNEQAWKEILKWEALHAHECPCGPSLVRFGGK 192

  Fly   183 AKDFSPRARFRSWLGYELPFDRHDWIVDRCGKDVRYVIDYYDGGLVDKDYRFALLDVRPAMDSVD 247
            |:::|||||.|||:||||||||||||::|||.:|||||||||||.|:|:|:|.:||||||.||..
Mouse   193 AREYSPRARIRSWMGYELPFDRHDWIINRCGTEVRYVIDYYDGGEVNKEYQFTILDVRPAFDSFS 257

  Fly   248 NVWDRMRVAYMRW 260
            .|||||:||:.||
Mouse   258 AVWDRMKVAWWRW 270

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Cchl	NP_651003.1	Cyto_heme_lyase	12..260	CDD:426167	149/270 (55%)
Hccs	NP_032248.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..62		19/60 (32%)
		Cyto_heme_lyase	5..270	CDD:426167	148/267 (55%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..116		19/39 (49%)