DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cchl and hccsa.2

DIOPT Version :9

Sequence 1:	NP_001262820.1	Gene:	Cchl / 42590	FlyBaseID:	FBgn0038925	Length:	281	Species:	Drosophila melanogaster
Sequence 2:	XP_017208122.2	Gene:	hccsa.2 / 101882578	ZFINID:	ZDB-GENE-090501-4	Length:	293	Species:	Danio rerio

Alignment Length:	144	Identity:	85/144 - (59%)
Similarity:	100/144 - (69%)	Gaps:	11/144 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 ECPMHQKHGD-AKSASAVPPHPKMQAA-SECPVQHDN------SDVNPLNMMPPANQQPAADQPF 90
            ||||||...| .|.|..||.|...... .|||::..|      ||:||.|||||.||||:|||||
Zfish   153 ECPMHQASKDHTKKAPDVPAHQDRACEFVECPMRAANGTKPTLSDINPANMMPPPNQQPSADQPF 217

  Fly    91 PLPTDRQTSTIPKVTEDGSVQFWQYPSQQMFWNAMLRKGWRWKTEDVSQKDMGDIIRIHNANNEQ 155
            ||...|:.||||:.   |:.:.|.|||:||||||||||||||...|::|.||||||:|||.||||
Zfish   218 PLSVVREESTIPRA---GAERNWVYPSEQMFWNAMLRKGWRWNKGDINQNDMGDIIKIHNQNNEQ 279

  Fly   156 AWQEVLKWEALHAK 169
            ||||:|:||.||:|
Zfish   280 AWQEILRWEKLHSK 293

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cchl	NP_001262820.1	Cyto_heme_lyase	13..260	CDD:279589	85/144 (59%)
hccsa.2	XP_017208122.2	PKc_like	<2..99	CDD:328722
hccsa.2	XP_017208122.2	Cyto_heme_lyase	143..>293	CDD:307431	84/142 (59%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1282808at2759
OrthoFinder	1	1.000	-	-		FOG0003033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R1787
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.950