Protein Alignment CG6028 and FAHD2A

DIOPT Version :9

• Sequence 1: NP_651002.3
• Gene: CG6028 / 42589
• FlyBaseID: FBgn0038924
• Length: 293
• Species: Drosophila melanogaster
• Sequence 2: XP_011509584.1
• Gene: FAHD2A / 51011
• HGNCID: 24252
• Length: 339
• Species: Homo sapiens
• Alignment Length: 284
• Identity: 126/284 - (44%)
• Similarity: 171/284 - (60%)
• Gaps: 34/284 - (11%)

  Fly     6 MRFVQYLRKGDLAKRLGLLSED--------------QKSLVEFAGLEGVPSDLKI----LIAQDP 52
            ||.||:.....:...|||.:.:              .|::.:|  ||...:.|.:    |.||.|
Human    27 MRLVQFRAPHLVGPHLGLETGNGGGVINLNAFDPTLPKTMTQF--LEQGEATLSVARRALAAQLP 89

  Fly    53 NLEELAKKAEKQPRLEVNDDVTLLPPLTDPGKIICIGLNYQDHCDEQNKPTPKEPLFFSKFNNAL 117
            .|          ||.|    ||.|.|:|.|.|::|:|:||.|||.|||.|.||||:.||||.:::
Human    90 VL----------PRSE----VTFLAPVTRPDKVVCVGMNYVDHCKEQNVPVPKEPIIFSKFASSI 140

  Fly   118 VGPQDNVIAHAASSKIDWEVELVCVIGKVARQVPKSQAMDYVFGYSVAQDISARDWQKERNGGQF 182
            |||.|.|:....|.::||||||..||||..:.:..:.||.:|.|::||.|:||||||..|||.|:
Human   141 VGPYDEVVLPPQSQEVDWEVELAVVIGKKGKHIKATDAMAHVAGFTVAHDVSARDWQMRRNGKQW 205

  Fly   183 LMGKSMDTFLPLGPAVVHKSLVPDVYNLNLKTWVNGVEKQNGNTGNLIFKLDDVINRLSQTITLL 247
            |:||:.|||.|||||:|.|..|.|.:||.:...|||...|:|||..::||.:|:|..:||.:|..
Human   206 LLGKTFDTFCPLGPALVTKDSVADPHNLKICCRVNGEVVQSGNTNQMVFKTEDLIAWVSQFVTFY 270

  Fly   248 PGDIIVTGTPKGVGMHRTPPEFLQ 271
            |||:|:||||.|||:.|.||.||:
Human   271 PGDVILTGTPPGVGVFRKPPVFLK 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6028	NP_651002.3	MhpD	37..293	CDD:223257	117/239 (49%)
		FAA_hydrolase	86..290	CDD:279845	99/186 (53%)
FAHD2A	XP_011509584.1	MhpD	51..284	CDD:223257	112/248 (45%)
		FAA_hydrolase	109..294	CDD:279845	98/184 (53%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	237	1.000	Domainoid score	I2325
eggNOG	1	0.900	-	-		E1_COG0179
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H9357
Inparanoid	1	1.050	253	1.000	Inparanoid score	I3209
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG62149
OrthoDB	1	1.010	-	-		D1216556at2759
OrthoFinder	1	1.000	-	-		FOG0006120
OrthoInspector	1	1.000	-	-		mtm8462
orthoMCL	1	0.900	-	-		OOG6_100403
Panther	1	1.100	-	-	LDO	PTHR42796
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R5268
SonicParanoid	1	1.000	-	-		X5055
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	15	14.870