Protein Alignment CG6028 and FAH

DIOPT Version :9

• Sequence 1: NP_651002.3
• Gene: CG6028 / 42589
• FlyBaseID: FBgn0038924
• Length: 293
• Species: Drosophila melanogaster
• Sequence 2: NP_000128.1
• Gene: FAH / 2184
• HGNCID: 3579
• Length: 419
• Species: Homo sapiens
• Alignment Length: 409
• Identity: 85/409 - (20%)
• Similarity: 137/409 - (33%)
• Gaps: 151/409 - (36%)

  Fly    14 KGDLAKRLGLLSEDQ---KSLVE--FAGLEGVPSDLKIL-----IAQDPNLEE---LAKKAEKQP 65
            :||...|:|:...||   .|:::  |.|        .:|     :...|.|..   |.:.|.|:.
Human    25 RGDPRPRIGVAIGDQILDLSIIKHLFTG--------PVLSKHQDVFNQPTLNSFMGLGQAAWKEA 81

  Fly    66 RL-----------EVNDD-------------VTLLPPLTDPGKIICIGLNYQDHCDEQNKPTPKE 106
            |:           .:.||             .|:..|.|       || :|.|....:...|...
Human    82 RVFLQNLLSVSQARLRDDTELRKCAFISQASATMHLPAT-------IG-DYTDFYSSRQHATNVG 138

  Fly   107 PLFFSKFNNALV-----------GPQDNVI---------------------AHAASSKIDWEVEL 139
            .:|..| .|||:           |...:|:                     .:.|...:|.|:|:
Human   139 IMFRDK-ENALMPNWLHLPVGYHGRASSVVVSGTPIRRPMGQMKPDDSKPPVYGACKLLDMELEM 202

  Fly   140 VCVIG---KVARQVPKSQAMDYVFGYSVAQDISARDWQKERNG--GQFLMGKS-----------M 188
            ...:|   ::...:|.|:|.:::||..:..|.||||.||....  |.|| |||           |
Human   203 AFFVGPGNRLGEPIPISKAHEHIFGMVLMNDWSARDIQKWEYVPLGPFL-GKSFGTTVSPWVVPM 266

  Fly   189 DTFLPLG-----------PAVVHKSLVPDVYNLNLKTWVNGVEKQNGNT---GNLIFKLDDVINR 239
            |..:|..           |.:.|..  |..:::||...:.|.......|   .|..:....::.:
Human   267 DALMPFAVPNPKQDPRPLPYLCHDE--PYTFDINLSVNLKGEGMSQAATICKSNFKYMYWTMLQQ 329

  Fly   240 LS----QTITLLPGDIIVTGTPKG-----------VGMHRTPP---------EFLQPGDVV---- 276
            |:    ....|.|||::.:||..|           :....|.|         :||..||.|
Human   330 LTHHSVNGCNLRPGDLLASGTISGPEPENFGSMLELSWKGTKPIDLGNGQTRKFLLDGDEVIITG 394

  Fly   277 ----QSEIVGLGKLCNKIV 291
                ....:|.|:...|::
Human   395 YCQGDGYRIGFGQCAGKVL 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG6028	NP_651002.3	MhpD	37..293	CDD:223257	76/381 (20%)
		FAA_hydrolase	86..290	CDD:279845	63/297 (21%)
FAH	NP_000128.1	fum_ac_acetase	2..416	CDD:162276	85/409 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0179
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810