Protein Alignment Mitofilin and SPBC3E7.05c

DIOPT Version :9

• Sequence 1: NP_001262819.1
• Gene: Mitofilin / 42587
• FlyBaseID: FBgn0019960
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_596092.1
• Gene: SPBC3E7.05c / 2541035
• PomBaseID: SPBC3E7.05c
• Length: 550
• Species: Schizosaccharomyces pombe
• Alignment Length: 638
• Identity: 117/638 - (18%)
• Similarity: 221/638 - (34%)
• Gaps: 191/638 - (29%)

  Fly   168 KKSKVEPVKATPAEEKRPSKPSEVSKTEAKPVSKPAAAAAPAPAAKPKDNPLPRDVVELEKAIEL 232
            |::|.||:...|..|:..|..|..||                                ..|...|
pombe    37 KQNKTEPIPFVPKPEEGSSNKSNSSK--------------------------------FRKRFLL 69

  Fly   233 SAQLAVKEYNVAIGVLKGFNDDVRKVVDKAVE----------NGENSLWTTLK----NRASARDT 283
            ...|.:..|:.:  |:..|.|.  ...|...|          |.|.| |...|    ||....|:
pombe    70 LFLLGITGYSCS--VVYCFKDP--NFYDYFAEHTPFGKQVLYNVEQS-WIGYKYLGGNRIKVDDS 129

  Fly   284 A---------VATAERAAREAQEKIVACEIALSAAATAQNAKKVEAVRDKIKKLVDHIGNVKDEL 339
            :         ::..:.::|....|:                 |.:...::.:.||..|.::..|:
pombe   130 SPKLKQNSNNISKKQNSSRNDDTKV-----------------KKDTTIERPESLVVEIVDLPSEV 177

  Fly   340 YRHKDTASVSDKYWRNVEKARNYFIDEIESIFPGLSLADKKLNLSKEDLDLFILHAYTHVLAYQK 404
              .||||  .:..|:::                ||   |::..||...:.: |.....|  |:::
pombe   178 --TKDTA--EESVWKDI----------------GL---DQETGLSVTAIPI-ITETLDH--AHEQ 216

  Fly   405 ELQRLQTDGELRLKRAIDSVRGDNDSEALRAQL-------EYHLEAERRKLAVENQKKI------ 456
            |::    |..||.:.::      |::..|..:|       |:..|...|:...|.:.|:
pombe   217 EIK----DQSLRFESSL------NEANELHGKLSKIQQEQEHLFEQRLREKVSEMESKLEALLIA 271

  Fly   457 ----FHIHAESDKLLRLQLKKQAEAHADHIKDIVAQRETDLTRSFKRELEDKLATE--------- 508
                :....||:| ||||...:|....:..|         |...|:.:|:::|..:
pombe   272 RDEKWQSAFESEK-LRLQKLHEARLQQELFK---------LASVFESKLKNELTEQAITLEKLHL 326

  Fly   509 ---KANYKLQLAGMLGKLRGMDAALAEIEDEFQERADAERTANQAQALWAACQALWASVRAATPG 570
               ||..:.:....||:|:       |:.:.||:..:..|..............:..::......
pombe   327 QSIKAQVEQERGSRLGRLQ-------ELRNSFQQLQELVRVVLHENGRVTRLVDVSNTLDDLNKD 384

  Fly   571 VHYKDRLRPLKNEINAIAKVAKGDDLVAAVLESVPKEAQERGVYPEDALRERFLNVER-VARRLA 634
            :.: .:|..::..:|.:.:..|.|:|.|.....:.|......:..::.|:.:|..:.: :.:...
pombe   385 MRF-HKLSEVRQHVNTLKEATKDDELAALASRVIEKIVDSGPILDKEELQTKFDTLSKEIYKTCF 448

  Fly   635 LVPEEGAGLPIYFLSYLQSLFILR--------PDNPISKDELENKPFDYSKLDTYDILNRARYHV 691
            |..|.|      |..:|:|:.:.:        ||....|..||:                ||.|:
pombe   449 LTTESG------FFGHLKSIILSQLPAAVFKSPDIVSVKKTLED----------------ARSHL 491

  Fly   692 DRSDFLQALKYMNLLQGASRKIAGEWMKEARLMLETQQAANTLMAHAAASGLL 744
            .:.|...:::.:..|....|.::.:|:...|..:|.|||...:.|.|..|..|
pombe   492 LKDDLDGSVRALLSLSQWPRALSRDWINACRRRMELQQAIEIIKASATLSSQL 544

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mitofilin	NP_001262819.1	Mitofilin	68..739	CDD:286774	114/631 (18%)
SPBC3E7.05c	NP_596092.1	Mitofilin	<123..539	CDD:286774	89/508 (18%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1854
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_103871
Panther	1	1.100	-	-	LDO	PTHR15415
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R4607
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.930