Protein Alignment Mitofilin and AgaP_AGAP002364

DIOPT Version :9

• Sequence 1: NP_001262819.1
• Gene: Mitofilin / 42587
• FlyBaseID: FBgn0019960
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: XP_003436101.1
• Gene: AgaP_AGAP002364 / 1273598
• VectorBaseID: AGAP002364
• Length: 746
• Species: Anopheles gambiae
• Alignment Length: 783
• Identity: 375/783 - (47%)
• Similarity: 526/783 - (67%)
• Gaps: 74/783 - (9%)

  Fly     1 MYRLAVRDQCKCALQRTLQQTTANNRQFGGSSSGSGGREQGRRQQEEQGQQGDQGYQGYQSLPPH 65
            ||||.|:.......:|...|..|.:|.:.||:.||                         :|||
Mosquito     1 MYRLLVQKALANNSKRPSAQLFAASRSYSGSARGS-------------------------NLPP- 39

  Fly    66 MREAGFGKVVLFVSPLAAVGGVITYAKYDDDFRKLVEKNVPGAGSVIKVALQEEPPFKGITKNVN 130
            ::|||||||::.:||:...|||:||||||::|||.:..|||....|:|..|||..|...::|.::
Mosquito    40 LQEAGFGKVLVVLSPILIGGGVVTYAKYDNEFRKTLITNVPALEPVLKTLLQETNPLDEVSKKMD 104

  Fly   131 DQIDKVKSGIETVTSTVDSVTSKVTGLFGGGSGDDKSKKS----------------------KVE 173
            |           ::.|:...||.:||.||||..:.|.:|.                      |.|
Mosquito   105 D-----------ISKTIGEYTSTITGFFGGGDEEKKQEKKPDLPPITRAKSVHVPVPSPPLPKPE 158

  Fly   174 PVKATPAEEKRPSKPSE-----VSKTEAKPVSKPAAAAAP---APAAKPKDNPL-------PRDV 223
            |:..:....::|.|..|     |:...|...:..|.||||   ||||..|..||       |:.:
Mosquito   159 PINLSDKVPEQPKKKPEAAAPKVTTATATKAAAAATAAAPAKSAPAAPSKPAPLASGGETVPKSI 223

  Fly   224 VELEKAIELSAQLAVKEYNVAIGVLKGFNDDVRKVVDKAVENGENSLWTTLKNRASARDTAVATA 288
            .:||:.:|::|.:|:|||..|:.|||.:.::||||||::|:..::|.||||:||.||||||:..|
Mosquito   224 SDLEQQVEVAATIAIKEYGHAVDVLKSYTNEVRKVVDESVDKLDSSSWTTLRNRTSARDTALQAA 288

  Fly   289 ERAAREAQEKIVACEIALSAAATAQNAKKVEAVRDKIKKLVDHIGNVKDELYRHKDTASVSDKYW 353
            |.||.:|:..|......|::.....:.:..:..|..|...:||:...|:|:|..:|.||:.:|||
Mosquito   289 EDAADKARGNIEKLHALLNSREIKCSDELKDKARQNIAAYLDHLKKAKEEVYAARDLASLGEKYW 353

  Fly   354 RNVEKARNYFIDEIESIFPGLSLADKKLNLSKEDLDLFILHAYTHVLAYQKELQRLQTDGELRLK 418
            :.||.|||||::|:||:|||::||::||||||::||||||||||.|:|:|||||:||.:|:..|:
Mosquito   354 KRVESARNYFVEEMESLFPGINLAERKLNLSKDELDLFILHAYTQVIAHQKELQKLQIEGDQNLR 418

  Fly   419 RAIDSVRGDNDSEALRAQLEYHLEAERRKLAVENQKKIFHIHAESDKLLRLQLKKQAEAHADHIK 483
            ||:::|||.:.||.::|:|||.:..|:|:|.:.||||:....||.::.:|.|||:|.|||.||:|
Mosquito   419 RALEAVRGSDQSEEVKARLEYEIAKEKRQLNLLNQKKLLLTRAELEQQMREQLKRQTEAHVDHLK 483

  Fly   484 DIVAQRETDLTRSFKRELEDKLATEKANYKLQLAGMLGKLRGMDAALAEIEDEFQERADAERTAN 548
            |.:.|:|.::.|.|:|||::|:.||:|:||||||.|||||:|:..||.||:.|.:|.||||::|:
Mosquito   484 DALTQKELEMKRKFQRELDEKITTEQASYKLQLAAMLGKLKGIHNALVEIDTEMKEHADAEKSAH 548

  Fly   549 QAQALWAACQALWASVRAATPGVHYKDRLRPLKNEINAIAKVAKGDDLVAAVLESVPKEAQERGV 613
            ||||||.|||:||:|:|:..||..::|:|||||:||.|:|:.|:||:||..||:.:|:.|.:|||
Mosquito   549 QAQALWGACQSLWSSIRSGQPGKSWRDQLRPLKDEIAAVARSAEGDELVTVVLKGLPETAVKRGV 613

  Fly   614 YPEDALRERFLNVERVARRLALVPEEGAGLPIYFLSYLQSLFILRPDNPISKDELENKPFDYSKL 678
            |||||||||||.||.|:|||||||.|||.||:|.|||||:..|.|||.|||:|||||||||:|||
Mosquito   614 YPEDALRERFLKVEEVSRRLALVPAEGARLPMYVLSYLQAALIARPDKPISQDELENKPFDFSKL 678

  Fly   679 DTYDILNRARYHVDRSDFLQALKYMNLLQGASRKIAGEWMKEARLMLETQQAANTLMAHAAASGL 743
            |||||||||||.:||.|.::.::|:||||||.||.|.:|:.||||:|||||||:||||||||||:
Mosquito   679 DTYDILNRARYWLDRGDLVKTVQYVNLLQGAPRKAALDWLNEARLLLETQQAASTLMAHAAASGV 743

  Fly   744 LYL 746
            .:|
Mosquito   744 RFL 746

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Mitofilin	NP_001262819.1	Mitofilin	68..739	CDD:286774	353/707 (50%)
AgaP_AGAP002364	XP_003436101.1	Mitofilin	42..739	CDD:286774	353/707 (50%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	678	1.000	Domainoid score	I487
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H38234
Inparanoid	1	1.050	694	1.000	Inparanoid score	I1884
OMA	1	1.010	-	-		QHG48742
OrthoDB	1	1.010	-	-		D1073064at2759
OrthoFinder	1	1.000	-	-		FOG0005100
OrthoInspector	1	1.000	-	-		oto106162
Panther	1	1.100	-	-	LDO	PTHR15415
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X4724
TreeFam	0	0.000	Not matched by this tool.
	11	11.080