Protein Alignment Idh3b and LYS12

DIOPT Version :9

• Sequence 1: NP_001163682.1
• Gene: Idh3b / 42586
• FlyBaseID: FBgn0038922
• Length: 370
• Species: Drosophila melanogaster
• Sequence 2: NP_012172.1
• Gene: LYS12 / 854714
• SGDID: S000001356
• Length: 371
• Species: Saccharomyces cerevisiae
• Alignment Length: 379
• Identity: 117/379 - (30%)
• Similarity: 181/379 - (47%)
• Gaps: 58/379 - (15%)

  Fly    19 RSLHT-TSTLRATDNYGANRT-TCTLIPGDGVGPELVYSLQEVFKAASVPVDFECYFLSEINPV- 80
            ||:.| .|..|...:..|.:: |..||||||:|.|::.:.::|              |..:|..
Yeast     3 RSVATRLSACRGLASNAARKSLTIGLIPGDGIGKEVIPAGKQV--------------LENLNSKH 53

  Fly    81 -LSAKLEDVVASIQKNKVCIKGVLATPDY-----------SNVGDLQTLNMK----------LRN 123
             ||....|:.|..|..:...|   |.||.           :..|.:|:...|          ||.
Yeast    54 GLSFNFIDLYAGFQTFQETGK---ALPDETVKVLKEQCQGALFGAVQSPTTKVEGYSSPIVALRR 115

  Fly   124 DLDLYANVVHVRSLPGVKTRHTNIDTVIIREQTEGEYSALEH---ESVPG--IVECLKIITAKKS 183
            ::.|:|||..|:|:.|.|.:  .||.||:||.||..|..:|.   :...|  :.:..|.|:...:
Yeast   116 EMGLFANVRPVKSVEGEKGK--PIDMVIVRENTEDLYIKIEKTYIDKATGTRVADATKRISEIAT 178

  Fly   184 MRIAKFAFDYATKNQRKK----VTAVHKANIMKLGDGLFLRSCEEV----SRLYPRIQFEKMIVD 240
            .|||..|.|.|.|..:.:    :|..||:|::...||||...|:||    ...|.:|::.:.|||
Yeast   179 RRIATIALDIALKRLQTRGQATLTVTHKSNVLSQSDGLFREICKEVYESNKDKYGQIKYNEQIVD 243

  Fly   241 NTTMQMVSNPNQFDVMVTPNLYGAIVDNLASGLVGGAGVVAGASYSSESVVFEPGARHTFAEAVG 305
            :...::...|..|||:|.|||||.|:.:.|:.|||..|||..|:...|.|:.|| ...:..:..|
Yeast   244 SMVYRLFREPQCFDVIVAPNLYGDILSDGAAALVGSLGVVPSANVGPEIVIGEP-CHGSAPDIAG 307

  Fly   306 KNVANPTAMLLCGVKLLRHINLPTYGEIIQNAINKVLNDGKVRTKDLGGQSTTQ 359
            |.:|||.|.:.....:|..:......:.|..|::..|.:|.::|.||||:::||
Yeast   308 KGIANPIATIRSTALMLEFLGHNEAAQDIYKAVDANLREGSIKTPDLGGKASTQ 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Idh3b	NP_001163682.1	Iso_dh	37..369	CDD:294303	111/360 (31%)
LYS12	NP_012172.1	LeuB	21..371	CDD:223549	111/361 (31%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810